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Biology and Biochemistry

D-Index
53
Citations
8711
World Ranking
16308
National Ranking
459

Overview

George C.T. Yeoh is affiliated with the Harry Perkins Institute of Medical Research in Australia. Their research predominantly focuses on Medicine and Biochemistry, Genetics and Molecular Biology, with a strong emphasis on Molecular Biology, Hepatology, Cancer Research, Surgery, and Epidemiology.

The scientist's primary research topics include:

  • Liver physiology and pathology
  • Liver Disease Diagnosis and Treatment
  • MicroRNA in disease regulation
  • Renal and related cancers
  • Cancer-related molecular mechanisms research
  • Organ Transplantation Techniques and Outcomes
  • Pluripotent Stem Cells Research

George C.T. Yeoh has contributed to several recent research papers, including:

  • "Building consensus on definition and nomenclature of hepatic, pancreatic, and biliary organoids" (2021) published in Cell stem cell
  • "Liver sinusoidal endothelial cells promote the differentiation and survival of mouse vascularised hepatobiliary organoids" (2020) published in Biomaterials
  • "Single-nucleus RNA sequencing of pre-malignant liver reveals disease-associated hepatocyte state with HCC prognostic potential" (2023) published in Cell Genomics
  • "Maraviroc Prevents HCC Development by Suppressing Macrophages and the Liver Progenitor Cell Response in a Murine Chronic Liver Disease Model" (2021) published in Cancers
  • "Subcellular mechano-microscopy: high resolution three-dimensional elasticity mapping using optical coherence microscopy" (2022) published in Optics Letters

The scientist frequently publishes in the following venues:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • International Journal of Molecular Sciences
  • Cell stem cell
  • Cell Genomics
  • Biomaterials

Collaborative work features frequent co-authors such as:

  • Janina E. E. Tirnitz-Parker
  • Stuart J. Forbes
  • Alistair R. R. Forrest
  • Kiryu K. Yap
  • Wayne A. Morrison

Best Publications

  • Oval Cell Numbers in Human Chronic Liver Diseases Are Directly Related to Disease Severity

    Kym N. Lowes;Barbara A. Brennan;George C. Yeoh;John K. Olynyk

  • Impaired Preneoplastic Changes and Liver Tumor Formation in Tumor Necrosis Factor Receptor Type 1 Knockout Mice

    Belinda Knight;George C.T. Yeoh;Kirsten L. Husk;Tina Ly

  • Generation and characterization of p53 null transformed hepatic progenitor cells: oval cells give rise to hepatocellular carcinoma

    Melissa L. Dumble;Emma J. Croager;George C.T. Yeoh;Elizabeth A Quail

  • TWEAK-FN14 signaling induces lysosomal degradation of a cIAP1–TRAF2 complex to sensitize tumor cells to TNFα

    James E. Vince;Diep Chau;Bernard Callus;W. Wei-Lynn Wong

  • A modified choline-deficient, ethionine-supplemented diet protocol effectively induces oval cells in mouse liver.

    Barbara Akhurst;Emma J. Croager;Caroline A. Farley-Roche;Jin Kar Ong

  • Effect of oncogenic virus on muscle differentiation

    H Holtzer;J Biehl;G Yeoh;R Meganathan

  • Establishment, characterization, and long-term maintenance of cultures of human fetal hepatocytes.

    Catherine A. Lázaro;Emma J. Croager;Claudia Mitchell;Jean S. Campbell

  • Oval cell-mediated liver regeneration: Role of cytokines and growth factors.

    Kym N Lowes;Emma J Croager;John K Olynyk;Lawrence J Abraham

  • Lineages, quantal cell cycles, and the generation of cell diversity.

    H. Holtzer;N. Rubinstein;S. Fellini;G. Yeoh

  • Transferrin receptors and iron uptake during erythroid cell development.

    B.J. Iacopetta;E.H. Morgan;G.C.T. Yeoh

  • Tumor necrosis factor–like weak inducer of apoptosis is a mitogen for liver progenitor cells

    Janina E. E. Tirnitz-Parker;Janina E. E. Tirnitz-Parker;Cornelia S. Viebahn;Aniela Jakubowski;Borut R. S. Klopcic

  • Transforming growth factor-beta differentially regulates oval cell and hepatocyte proliferation.

    Lananh N. Nguyen;Momoko H. Furuya;Lawrence A. Wolfraim;Anthony P. Nguyen

  • Uptake and cytotoxicity of chitosan nanoparticles in human liver cells.

    Jing Wen Loh;George Yeoh;Martin Saunders;Lee-Yong Lim

  • In Vivo Differentiation of Mouse Embryonic Stem Cells into Hepatocytes

    Dongho Choi;Hyun-Jeong Oh;Uck-Jin Chang;Soo Kyung Koo

  • Differential lymphotoxin‐β and interferon gamma signaling during mouse liver regeneration induced by chronic and acute injury

    Barbara Akhurst;Vance Matthews;Kirsten Husk;Mark J. Smyth

  • Liver stem cells: A scientific and clinical perspective

    Yock Young Dan;Yock Young Dan;George C Yeoh

  • Isolation, culture and immortalisation of hepatic oval cells from adult mice fed a choline-deficient, ethionine-supplemented diet

    Janina E.E. Tirnitz-Parker;Joanne N. Tonkin;Belinda Knight;John K. Olynyk

  • Opposing roles of gp130-mediated STAT-3 and ERK-1/2 signaling in liver progenitor cell migration and proliferation

    George C.T. Yeoh;Matthias Ernst;Stefan Rose-John;Barbara Akhurst

  • Interferon-γ exacerbates liver damage, the hepatic progenitor cell response and fibrosis in a mouse model of chronic liver injury

    Belinda Knight;Rebecca Lim;George C. Yeoh;John K. Olynyk;John K. Olynyk

  • Receptor-mediated endocytosis of transferrin by developing erythroid cells from the fetal rat liver.

    B J Iacopetta;E H Morgan;G C Yeoh

Frequent Co-Authors

Evan H. Morgan
Evan H. Morgan University of Western Australia
Howard Holtzer
Howard Holtzer University of Pennsylvania
Ian E. Alexander
Ian E. Alexander University of Sydney
David L. Vaux
David L. Vaux Walter and Eliza Hall Institute of Medical Research
James E. Vince
James E. Vince Walter and Eliza Hall Institute of Medical Research
Aleksandra Filipovska
Aleksandra Filipovska University of Western Australia
Paul G Ekert
Paul G Ekert University of New South Wales
Nelson Fausto
Nelson Fausto University of Washington
Jean S. Campbell
Jean S. Campbell University of Washington
David D. Sampson
David D. Sampson University of Surrey

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