Paul G Ekert

Overview

Best Publications

• Identification of DIABLO, a Mammalian Protein that Promotes Apoptosis by Binding to and Antagonizing IAP Proteins

  Anne M Verhagen;Paul G Ekert;Paul G Ekert;Miha Pakusch;John Silke

  3288
  Citations

• Programmed Anuclear Cell Death Delimits Platelet Life Span

  Kylie D Mason;Marina Carpinelli;Jamie I Fletcher;Janelle Elyse Collinge

  1175
  Citations

• HtrA2 promotes cell death through its serine protease activity and its ability to antagonize inhibitor of apoptosis proteins.

  Anne M Verhagen;John Silke;Paul G Ekert;Paul G Ekert;Miha Pakusch

  788
  Citations

• Apoptosis initiated by Bcl-2-regulated caspase activation independently of the cytochrome c/Apaf-1/caspase-9 apoptosome

  Vanessa S. Marsden;Liam O'Connor;Liam O'Connor;Lorraine A. O'Reilly;John Silke

  722
  Citations

• Heritable GATA2 mutations associated with familial myelodysplastic syndrome and acute myeloid leukemia

  Christopher N. Hahn;Christopher N. Hahn;Chan-Eng Chong;Chan-Eng Chong;Catherine L. Carmichael;Ella J. Wilkins;Ella J. Wilkins

  701
  Citations

• RIPK1 regulates RIPK3-MLKL-driven systemic inflammation and emergency hematopoiesis.

  James A Rickard;James A Rickard;Joanne A O'Donnell;Joanne A O'Donnell;Joseph M Evans;Joseph M Evans;Najoua Lalaoui;Najoua Lalaoui

  634
  Citations

• Nano-targeted induction of dual ferroptotic mechanisms eradicates high-risk neuroblastoma

  Behrouz Hassannia;Bartosz Wiernicki;Irina Ingold;Feng Qu

  618
  Citations

• A prospective evaluation of whole-exome sequencing as a first-tier molecular test in infants with suspected monogenic disorders

  Zornitza Stark;Tiong Y. Tan;Belinda Chong;Gemma R. Brett

  378
  Citations

• The granulocyte-macrophage colony-stimulating factor receptor: linking its structure to cell signaling and its role in disease

  Timothy R Hercus;Daniel Thomas;Mark Andrew Guthridge;Paul G Ekert

  356
  Citations

• Whole genome, transcriptome and methylome profiling enhances actionable target discovery in high-risk pediatric cancer.

  Marie Wong;Marie Wong;Chelsea Mayoh;Loretta M.S. Lau;Loretta M.S. Lau;Dong Anh Khuong-Quang

  271
  Citations

• DIABLO promotes apoptosis by removing MIHA/XIAP from processed caspase 9.

  Paul G. Ekert;John Hendry. Silke;Christine Joy. Hawkins;Anne. Verhagen

  266
  Citations

• The BH3-Only Protein Bid Is Dispensable for DNA Damage- and Replicative Stress-Induced Apoptosis or Cell-Cycle Arrest

  Thomas Kaufmann;Lin Tai;Paul G. Ekert;Paul G. Ekert;David C.S. Huang

  243
  Citations

• Apaf-1 and caspase-9 accelerate apoptosis, but do not determine whether factor-deprived or drug-treated cells die.

  Paul G. Ekert;Paul G. Ekert;Stuart H. Read;John Silke;Vanessa S. Marsden

  223
  Citations

• Caspase-2 is not required for thymocyte or neuronal apoptosis even though cleavage of caspase-2 is dependent on both Apaf-1 and caspase-9.

  L A O'Reilly;P Ekert;N Harvey;V Marsden

  218
  Citations

• The molecular relationships between apoptosis, autophagy and necroptosis

  Najoua Lalaoui;Najoua Lalaoui;Lisa M. Lindqvist;Lisa M. Lindqvist;Jarrod J. Sandow;Jarrod J. Sandow;Paul G. Ekert

  205
  Citations

• Determination of cell survival by RING-mediated regulation of inhibitor of apoptosis (IAP) protein abundance.

  John Silke;Tobias Kratina;Diep Chu;Paul G. Ekert

  204
  Citations

• A novel Apaf-1-independent putative caspase-2 activation complex.

  Stuart H. Read;Belinda C. Baliga;Paul G. Ekert;David L. Vaux

  194
  Citations

• Germline HAVCR2 mutations altering TIM-3 characterize subcutaneous panniculitis-like T cell lymphomas with hemophagocytic lymphohistiocytic syndrome

  Tenzin Gayden;Fernando E. Sepulveda;Dong-Anh Khuong-Quang;Dong-Anh Khuong-Quang;Jonathan Pratt

  192
  Citations

• Lysosomal membrane permeabilization and cathepsin release is a Bax/Bak-dependent, amplifying event of apoptosis in fibroblasts and monocytes.

  C Oberle;J Huai;T Reinheckel;M Tacke

  189
  Citations

• Patient safety in genomic medicine: an exploratory study.

  Diane M. Korngiebel;Stephanie M. Fullerton;Wylie Burke

  15
  Citations