What is he best known for?
The fields of study he is best known for:
The scientist’s investigation covers issues in Cell biology, Programmed cell death, Inhibitor of apoptosis, XIAP and Apoptosis.
His Cell biology research is multidisciplinary, incorporating elements of NFKB1 and Ubiquitin, Ubiquitin ligase.
His studies in Programmed cell death integrate themes in fields like Tumor necrosis factor alpha and Inflammasome.
His Inhibitor of apoptosis study incorporates themes from Gene and Locus.
His XIAP research is multidisciplinary, incorporating perspectives in Cancer research, Baculoviral IAP repeat-containing protein 3 and XIAP Deficiency.
A large part of his Necroptosis studies is devoted to RIPK1.
His most cited work include:
- Identification of DIABLO, a Mammalian Protein that Promotes Apoptosis by Binding to and Antagonizing IAP Proteins (2122 citations)
- Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018. (1421 citations)
- Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018. (1421 citations)
What are the main themes of his work throughout his whole career to date?
John Silke mainly focuses on Cell biology, Programmed cell death, Cancer research, Necroptosis and Inhibitor of apoptosis.
His work carried out in the field of Cell biology brings together such families of science as Caspase and Ubiquitin.
Programmed cell death is a subfield of Apoptosis that John Silke investigates.
His work in Cancer research tackles topics such as Tumor necrosis factor alpha which are related to areas like NFKB1 and Cytokine.
His Necroptosis study integrates concerns from other disciplines, such as Pyroptosis and Protein kinase A.
John Silke usually deals with Inhibitor of apoptosis and limits it to topics linked to XIAP and XIAP Deficiency, Baculoviral IAP repeat-containing protein 3, Molecular biology, RIPK2 and Proinflammatory cytokine.
He most often published in these fields:
- Cell biology (78.96%)
- Programmed cell death (73.17%)
- Cancer research (57.93%)
What were the highlights of his more recent work (between 2017-2021)?
- Programmed cell death (73.17%)
- Cell biology (78.96%)
- Necroptosis (53.66%)
In recent papers he was focusing on the following fields of study:
His main research concerns Programmed cell death, Cell biology, Necroptosis, Cancer research and Inhibitor of apoptosis.
His Programmed cell death research is under the purview of Apoptosis.
His biological study spans a wide range of topics, including XIAP and Ubiquitin, Ubiquitin ligase.
His Necroptosis research includes themes of Inflammation, Pyroptosis, Phosphorylation and Effector.
The concepts of his Cancer research study are interwoven with issues in Tumor necrosis factor alpha, Missense mutation, Carcinogenesis and Immunotherapy.
His research integrates issues of Caspase, Chimeric antigen receptor, Cell growth and In vivo in his study of Inhibitor of apoptosis.
Between 2017 and 2021, his most popular works were:
- Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018. (1421 citations)
- Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018. (1421 citations)
- Tumor immune evasion arises through loss of TNF sensitivity (87 citations)
In his most recent research, the most cited papers focused on:
John Silke mainly investigates Necroptosis, Cell biology, Programmed cell death, RIPK1 and Kinase activity.
The study incorporates disciplines such as Inhibitor of apoptosis, Bcl-xL, XIAP and Caspase 7 in addition to Cell biology.
His research on Programmed cell death concerns the broader Apoptosis.
His Apoptosis study combines topics in areas such as Receptor and Neuroscience.
His RIPK1 research incorporates elements of Caspase, Caspase 8 and Signal transduction.
His Caspase 8 research is multidisciplinary, incorporating elements of Inflammation, Cancer research and Tumor necrosis factor alpha.
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