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Immunology

D-Index
52
Citations
11509
World Ranking
4044
National Ranking
171

Overview

Marc Pellegrini is affiliated with the Walter and Eliza Hall Institute of Medical Research in Australia. Their research spans multiple disciplines primarily within medicine, immunology, microbiology, and molecular biology.

The main fields of study for Pellegrini include:

  • Medicine
  • Immunology and Microbiology
  • Biochemistry, Genetics and Molecular Biology

Subfields of their work further focus on:

  • Immunology
  • Infectious Diseases
  • Molecular Biology
  • Epidemiology
  • Oncology

Their research topics cover a range of immunological and infectious disease themes with a significant emphasis on SARS-CoV-2 and COVID-19. Key topics include:

  • SARS-CoV-2 and COVID-19 Research
  • Immunotherapy and Immune Responses
  • Cell death mechanisms and regulation
  • Inflammasome and immune disorders
  • Immune Cell Function and Interaction
  • interferon and immune responses
  • COVID-19 Clinical Research Studies

Pellegrini has published extensively in several journals. Frequent publication venues include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Immunity
  • Nature Communications
  • Cell Death and Disease
  • The EMBO Journal

Notable recent papers authored with Pellegrini's involvement are:

  • "Mechanism and inhibition of the papain-like protease, PLpro, of SARS-CoV-2" (2020), The EMBO Journal
  • "Nanobody cocktails potently neutralize SARS-CoV-2 D614G N501Y variant and protect mice" (2021), Proceedings of the National Academy of Sciences
  • "Flexible Usage and Interconnectivity of Diverse Cell Death Pathways Protect against Intracellular Infection" (2020), Immunity
  • "Interferon-γ primes macrophages for pathogen ligand-induced killing via a caspase-8 and mitochondrial cell death pathway" (2022), Immunity
  • "Effector and stem-like memory cell fates are imprinted in distinct lymph node niches directed by CXCR3 ligands" (2021), Nature Immunology

The scientist has collaborated frequently with a number of colleagues in their field. Regular co-authors include:

  • Marcel Doerflinger
  • James P. Cooney
  • Cody C. Allison
  • Liana Mackiewicz
  • Stefanie M. Bader

Best Publications

  • Hobit and Blimp1 instruct a universal transcriptional program of tissue residency in lymphocytes.

    Laura K. Mackay;Laura K. Mackay;Martina Minnich;Natasja A. M. Kragten;Yang Liao;Yang Liao

  • BH3-only Bcl-2 family member Bim is required for apoptosis of autoreactive thymocytes.

    Philippe Bouillet;Jared F. Purton;Dale I. Godfrey;Li-Chen Zhang

  • FOXO3a-dependent regulation of Puma in response to cytokine/growth factor withdrawal

    Han You;Marc Pellegrini;Marc Pellegrini;Katsuya Tsuchihara;Katsuya Tsuchihara;Kazuo Yamamoto;Kazuo Yamamoto

  • Transcription factor IRF4 Promotes CD8 + T cell exhaustion and limits the development of memory-like T cells during chronic infection

    Kevin Man;Sarah S. Gabriel;Yang Liao;Yang Liao;Renee Gloury;Renee Gloury

  • CXCR5 + follicular cytotoxic T cells control viral infection in B cell follicles

    Yew Ann Leong;Yaping Chen;Hong Sheng Ong;Di Wu

  • Mechanism and inhibition of the papain-like protease, PLpro, of SARS-CoV-2.

    Theresa Klemm;Gregor Ebert;Dale J Calleja;Cody C Allison

  • The transcription factor IRF4 is essential for TCR affinity–mediated metabolic programming and clonal expansion of T cells

    Kevin Man;Maria Miasari;Maria Miasari;Wei Shi;Wei Shi;Annie Xin;Annie Xin

  • IL-7 Engages Multiple Mechanisms to Overcome Chronic Viral Infection and Limit Organ Pathology

    Marc Pellegrini;Thomas Calzascia;Jesse G. Toe;Simon P. Preston

  • NLRP1 Inflammasome Activation Induces Pyroptosis of Hematopoietic Progenitor Cells

    Seth L. Masters;Motti Gerlic;Motti Gerlic;Donald Metcalf;Donald Metcalf;Simon Preston;Simon Preston

  • TNF-α is critical for antitumor but not antiviral T cell immunity in mice

    Thomas Calzascia;Marc Pellegrini;Håkan Hall;Laurent Sabbagh;Laurent Sabbagh

  • Shutdown of an acute T cell immune response to viral infection is mediated by the proapoptotic Bcl-2 homology 3-only protein Bim

    Marc Pellegrini;Gabrielle Belz;Philippe Bouillet;Andreas Strasser

  • Adjuvant IL-7 antagonizes multiple cellular and molecular inhibitory networks to enhance immunotherapies

    Marc Pellegrini;Thomas Calzascia;Thomas Calzascia;Alisha R Elford;Arda Shahinian

  • Analysis of the apoptotic and therapeutic activities of histone deacetylase inhibitors by using a mouse model of B cell lymphoma

    Ralph K Lindemann;Andrea Newbold;K F Whitecross;Leonie A Cluse

  • T-lymphocyte death during shutdown of an immune response

    Andreas Strasser;Marc Pellegrini

  • Severe Malaria Infections Impair Germinal Center Responses by Inhibiting T Follicular Helper Cell Differentiation

    Victoria Ryg-Cornejo;Victoria Ryg-Cornejo;Lisa Julia Ioannidis;Lisa Julia Ioannidis;Ann Ly;Ann Ly;Chris Yu Chiu;Chris Yu Chiu

  • Role of PI3K/Akt signaling in memory CD8 T cell differentiation

    Eui Ho Kim;M. Suresh

  • A molecular threshold for effector CD8+ T cell differentiation controlled by transcription factors Blimp-1 and T-bet

    Annie Xin;Frederick Masson;Frederick Masson;Frederick Masson;Yang Liao;Yang Liao;Simon Peter Preston;Simon Peter Preston

  • CD4 T cells, lymphopenia, and IL-7 in a multistep pathway to autoimmunity

    Thomas Calzascia;Marc Pellegrini;Albert Lin;Kristine M. Garza

  • Loss of Bim Increases T Cell Production and Function in Interleukin 7 Receptor–deficient Mice

    Marc Pellegrini;Philippe Bouillet;Mikara Robati;Gabrielle T. Belz

  • Fatal Hepatitis Mediated by Tumor Necrosis Factor TNFα Requires Caspase-8 and Involves the BH3-Only Proteins Bid and Bim

    Thomas Kaufmann;Philipp J. Jost;Marc Pellegrini;Hamsa Puthalakath

  • Nanobody cocktails potently neutralize SARS-CoV-2 D614G N501Y variant and protect mice.

    Phillip Pymm;Phillip Pymm;Amy Adair;Li-Jin Chan;Li-Jin Chan;James P Cooney;James P Cooney

Frequent Co-Authors

Gabrielle T. Belz
Gabrielle T. Belz University of Queensland
Andreas Strasser
Andreas Strasser Walter and Eliza Hall Institute of Medical Research
Pamela S. Ohashi
Pamela S. Ohashi Princess Margaret Cancer Centre
John Silke
John Silke Walter and Eliza Hall Institute of Medical Research
Axel Kallies
Axel Kallies University of Melbourne
Tak W. Mak
Tak W. Mak Princess Margaret Cancer Centre
Gordon K. Smyth
Gordon K. Smyth Walter and Eliza Hall Institute of Medical Research
Stephen L. Nutt
Stephen L. Nutt Walter and Eliza Hall Institute of Medical Research
Donald Metcalf
Donald Metcalf Walter and Eliza Hall Institute of Medical Research
Philippe Bouillet
Philippe Bouillet Walter and Eliza Hall Institute of Medical Research

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