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Immunology

D-Index
78
Citations
27049
World Ranking
1730
National Ranking
64

Overview

Axel Kallies is affiliated with the University of Melbourne in Australia and has established a substantial body of research primarily within the fields of Immunology and Microbiology, as well as Medicine. Their work encompasses various subfields including Immunology, Oncology, Genetics, Ecology, Evolution, Behavior and Systematics, and Molecular Biology.

The main topics of Axel Kallies' research focus on Immune Cell Function and Interaction, T-cell and B-cell Immunology, Immunotherapy and Immune Responses, Lepidoptera Biology and Taxonomy, CAR-T cell therapy research, Cancer Immunotherapy and Biomarkers, and Plant and animal studies.

Axel Kallies has published extensively in several scientific venues. The most frequent publication venues include:

  • Nature Immunology
  • Zootaxa
  • Immunity
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Science Immunology

Notable recent papers authored or co-authored by Axel Kallies include:

  • "Early precursor T cells establish and propagate T cell exhaustion in chronic infection," 2020, Nature Immunology
  • "MYB orchestrates T cell exhaustion and response to checkpoint inhibition," 2022, Nature
  • "Discrete tissue microenvironments instruct diversity in resident memory T cell function and plasticity," 2021, Nature Immunology
  • "Sex-specific adipose tissue imprinting of regulatory T cells," 2020, Nature
  • "Cellular networks controlling T cell persistence in adoptive cell therapy," 2021, Nature reviews. Immunology

Their collaborative network includes frequent co-authors such as Ajithkumar Vasanthakumar, Daniel T. Utzschneider, Carlson Tsui, Wei Shi, and Sarah S. Gabriel.

Axel Kallies' research engages with topics related to the immune system's cellular dynamics and responses, contributing to areas like T cell exhaustion, regulatory T cell function, adoptive cell therapies, and the influence of tissue microenvironments on immune cells. The integration of oncology and immunotherapy themes highlights a focus on therapeutic approaches and immune response mechanisms relevant to cancer and chronic infection contexts.

Best Publications

  • Defining ‘T cell exhaustion’

    Christian U Blank;W Nicholas Haining;Werner Held;Patrick G Hogan;Patrick G Hogan

  • Foxp3+ follicular regulatory T cells control the germinal center response

    Michelle A. Linterman;Wim Pierson;Sau K. Lee;Axel Kallies

  • Hobit and Blimp1 instruct a universal transcriptional program of tissue residency in lymphocytes.

    Laura K. Mackay;Laura K. Mackay;Martina Minnich;Natasja A. M. Kragten;Yang Liao;Yang Liao

  • IL-21 regulates germinal center B cell differentiation and proliferation through a B cell-intrinsic mechanism.

    Dimitra Zotos;Jonathan M. Coquet;Yang Zhang;Amanda Light

  • The transcription factors Blimp-1 and IRF4 jointly control the differentiation and function of effector regulatory T cells

    Erika Cretney;Annie Xin;Annie Xin;Wei Shi;Wei Shi;Martina Minnich

  • Microbiota-Derived Short-Chain Fatty Acids Promote the Memory Potential of Antigen-Activated CD8+ T Cells

    Annabell Bachem;Christina Makhlouf;Katrina J. Binger;David P. de Souza

  • T-box Transcription Factors Combine with the Cytokines TGF-β and IL-15 to Control Tissue-Resident Memory T Cell Fate

    Laura K. Mackay;Erica Wynne-Jones;David Freestone;Daniel G. Pellicci;Daniel G. Pellicci

  • Blimp-1 Transcription Factor Is Required for the Differentiation of Effector CD8+ T Cells and Memory Responses

    Axel Kallies;Annie Xin;Annie Xin;Gabrielle T. Belz;Stephen L. Nutt

  • Plasma Cell Ontogeny Defined by Quantitative Changes in Blimp-1 Expression

    Axel Kallies;Jhagvaral Hasbold;David M. Tarlinton;Wendy Dietrich

  • Interleukin-10-Producing Plasmablasts Exert Regulatory Function in Autoimmune Inflammation

    Masanori Matsumoto;Akemi Baba;Takafumi Yokota;Hiroyoshi Nishikawa

  • The transcriptional regulators IRF4, BATF and IL-33 orchestrate development and maintenance of adipose tissue-resident regulatory T cells

    Ajithkumar Vasanthakumar;Kazuyo Moro;Annie Xin;Yang Liao

  • Transcription factor IRF4 Promotes CD8 + T cell exhaustion and limits the development of memory-like T cells during chronic infection

    Kevin Man;Sarah S. Gabriel;Yang Liao;Yang Liao;Renee Gloury;Renee Gloury

  • CXCR5 + follicular cytotoxic T cells control viral infection in B cell follicles

    Yew Ann Leong;Yaping Chen;Hong Sheng Ong;Di Wu

  • Precursor exhausted T cells: key to successful immunotherapy?

    Axel Kallies;Dietmar Zehn;Daniel T Utzschneider

  • The transcription factor IRF4 is essential for TCR affinity–mediated metabolic programming and clonal expansion of T cells

    Kevin Man;Maria Miasari;Maria Miasari;Wei Shi;Wei Shi;Annie Xin;Annie Xin

  • Transcriptional repressor Blimp-1 is essential for T cell homeostasis and self-tolerance

    Axel Kallies;Edwin D Hawkins;Gabrielle T Belz;Donald Metcalf

  • The development and fate of follicular helper T cells defined by an IL-21 reporter mouse.

    Katja Lüthje;Axel Kallies;Yoko Shimohakamada;Gabrielle T Belz

  • Blimp-1 controls plasma cell function through the regulation of immunoglobulin secretion and the unfolded protein response

    Julie Tellier;Julie Tellier;Wei Shi;Wei Shi;Martina Minnich;Yang Liao;Yang Liao

  • Cleavage of roquin and regnase-1 by the paracaspase MALT1 releases their cooperatively repressed targets to promote T(H)17 differentiation

    Katharina M. Jeltsch;Desheng Hu;Sven Brenner;Jessica Zöller

  • Early appearance of germinal center–derived memory B cells and plasma cells in blood after primary immunization

    Elizabeth J. Blink;Amanda Light;Axel Kallies;Stephen L. Nutt

  • Foxp3(+) follicular regulatory T cells control the germinal centre response

    M. A Linterman;Wim Pierson;S. K Lee;A Kallies

Frequent Co-Authors

Stephen L. Nutt
Stephen L. Nutt Walter and Eliza Hall Institute of Medical Research
Gabrielle T. Belz
Gabrielle T. Belz University of Queensland
Wei Shi
Wei Shi Monash University
Gordon K. Smyth
Gordon K. Smyth Walter and Eliza Hall Institute of Medical Research
Lynn M. Corcoran
Lynn M. Corcoran Walter and Eliza Hall Institute of Medical Research
David M. Tarlinton
David M. Tarlinton Monash University
Marc Pellegrini
Marc Pellegrini Walter and Eliza Hall Institute of Medical Research
Philip D. Hodgkin
Philip D. Hodgkin Walter and Eliza Hall Institute of Medical Research
Mark A. Febbraio
Mark A. Febbraio Monash University
Andreas Strasser
Andreas Strasser Walter and Eliza Hall Institute of Medical Research

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