Lynn M. Corcoran mainly investigates Cellular differentiation, Molecular biology, Cell biology, B cell and Antibody. The study incorporates disciplines such as Lymphocyte differentiation and Immunology in addition to Cellular differentiation. His work deals with themes such as Regulation of gene expression, Gene rearrangement, Gene, Immunoglobulin light chain and Provirus, which intersect with Molecular biology.
His study looks at the relationship between Cell biology and fields such as Antigen-presenting cell, as well as how they intersect with chemical problems. As a part of the same scientific study, Lynn M. Corcoran usually deals with the B cell, concentrating on B-1 cell and frequently concerns with Naive B cell. He has included themes like Enhancer and Antigen in his Antibody study.
His primary scientific interests are in Cell biology, Molecular biology, B cell, Cellular differentiation and Immunology. His biological study spans a wide range of topics, including Cell, T cell, Antigen presentation, Antigen-presenting cell and Germinal center. The Molecular biology study which covers Enhancer that intersects with Lymphoma and Oncogene.
His B cell study integrates concerns from other disciplines, such as Plasma cell, Transcription factor and B-1 cell. His Cellular differentiation research integrates issues from Regulation of gene expression, Antibody, Gene rearrangement and CD40. His studies in Regulation of gene expression integrate themes in fields like Cancer research and PRDM1.
Lynn M. Corcoran mostly deals with Cell biology, Immune system, Immunology, B cell and Germinal center. His Cell biology study combines topics in areas such as Plasma cell, Cellular differentiation, T cell, Transcription factor and Interleukin 15. His work on Plasma cell differentiation as part of general Plasma cell study is frequently connected to XBP1, therefore bridging the gap between diverse disciplines of science and establishing a new relationship between them.
His studies deal with areas such as Cytotoxic T cell, Antibody, Monoclonal antibody and Virology as well as Immune system. The Antigen, Chemokine receptor and Chemokine research Lynn M. Corcoran does as part of his general Immunology study is frequently linked to other disciplines of science, such as Devil facial tumour disease, therefore creating a link between diverse domains of science. He studies B cell, namely Immunoglobulin class switching.
His scientific interests lie mostly in Cell biology, B cell, T cell, Germinal center and Cellular differentiation. His Cell biology research incorporates themes from Interleukin 12, Molecular biology and Interleukin 21. The B cell study combines topics in areas such as Immune system and Programmed cell death.
His T cell research includes themes of Lymphocyte proliferation, Cell, Cell division, Cell growth and Signal transduction. His Germinal center research incorporates themes from Plasma cell, Transcription factor, Plasma cell differentiation, Germline and Priming. The study incorporates disciplines such as Interleukin 15, Lymphokine-activated killer cell, Natural killer cell, Innate lymphoid cell and Cell fate determination in addition to Cellular differentiation.
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The c- myc oncogene driven by immunoglobulin enhancers induces lymphoid malignancy in transgenic mice
J. M. Adams;A. W. Harris;C. A. Pinkert;L. M. Corcoran.
The generation of antibody-secreting plasma cells.
Stephen L Nutt;Philip D Hodgkin;David M Tarlinton;Lynn M Corcoran.
Nature Reviews Immunology (2015)
The POU domain: a large conserved region in the mammalian pit-1, oct-1, oct-2, and Caenorhabditis elegans unc-86 gene products
W Herr;R A Sturm;R G Clerc;L M Corcoran.
Genes & Development (1988)
Genetic analysis of the human malaria parasite plasmodium falciparum
David Walliker;Isabella A. Quakyi;Thomas E. Wellems;Thomas F. McCutchan.
IL-21 regulates germinal center B cell differentiation and proliferation through a B cell-intrinsic mechanism.
Dimitra Zotos;Jonathan M. Coquet;Yang Zhang;Amanda Light.
Journal of Experimental Medicine (2010)
Regulatory T-cell suppressor program co-opts transcription factor IRF4 to control T H 2 responses
Ye Zheng;Ashutosh Chaudhry;Ashutosh Chaudhry;Arnold Kas;Paul deRoos;Paul deRoos.
Bcl-2 can rescue T lymphocyte development in interleukin-7 receptor-deficient mice but not in mutant rag-1-/- mice
Eugene Maraskovsky;Lorraine A O'Reilly;Mark Teepe;Lynn M Corcoran.
Plasma Cell Ontogeny Defined by Quantitative Changes in Blimp-1 Expression
Axel Kallies;Jhagvaral Hasbold;David M. Tarlinton;Wendy Dietrich.
Journal of Experimental Medicine (2004)
Cytokine-Mediated Regulation of Human B Cell Differentiation into Ig-Secreting Cells: Predominant Role of IL-21 Produced by CXCR5+ T Follicular Helper Cells
Vanessa L. Bryant;Vanessa L. Bryant;Vanessa L. Bryant;Cindy S. Ma;Cindy S. Ma;Danielle T. Avery;Danielle T. Avery;Ying Li.
Journal of Immunology (2007)
Functional immunoglobulin transgenes guide ordered B-cell differentiation in Rag-1-deficient mice.
Eugenia Spanopoulou;Christopher A. J. Roman;Lynn M. Corcoran;Mark S. Schlissel.
Genes & Development (1994)
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