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Biology and Biochemistry
Australia
2023

D-Index & Metrics

Biology and Biochemistry

D-Index
71
Citations
23326
World Ranking
6546
National Ranking
158

Research.com Recognitions

  • 2023 - Research.com Biology and Biochemistry in Australia Leader Award

Overview

Lynn M. Corcoran is affiliated with the Walter and Eliza Hall Institute of Medical Research in Australia. Their research primarily focuses on immunology and microbiology, with a significant emphasis on immune cell function and interaction and T-cell and B-cell immunology. Their work also covers topics related to IL-33, ST2, and ILC pathways, as well as CAR-T cell therapy research.

Corcoran has contributed to several publications across notable scientific venues. Frequent publication outlets include:

  • The Journal of Immunology
  • Nature Communications
  • Science Immunology
  • bioRxiv (Cold Spring Harbor Laboratory)

Their recent papers reflect a focus on regulatory T cell function and immunological homeostasis. These include:

  • "Attenuation of TCR-induced transcription by Bach2 controls regulatory T cell differentiation and homeostasis," 2020, Nature Communications
  • "Zbtb20 identifies and controls a thymus-derived population of regulatory T cells that play a role in intestinal homeostasis," 2022, Science Immunology
  • "Expression of a BTB-ZF transcription factor controls the function of an innate-like Tregs essential for intestinal homeostasis," 2022, The Journal of Immunology
  • "Specific expression of a BTB-ZF transcription factor defines innate-like regulatory T cells that are essential for intestinal homeostasis," 2021, The Journal of Immunology
  • "Early, adjuvant-responsive epigenetic programs in B cells imprint subsequent plasma cell survival and the duration of humoral immunity," 2025, bioRxiv (Cold Spring Harbor Laboratory)

Frequent collaborators in Corcoran's research include the following scientists:

  • Agata Krzyzanowska
  • Damián Kovalovsky
  • Karen L. Edelblum
  • Arnold B. Rabson
  • Lisa Denzin

The main fields of study for Corcoran's work are immunology and microbiology, with most of their research centered on immunology. Subfields include:

  • Immunology
  • Oncology

The main topics researched and published by Corcoran comprise:

  • Immune Cell Function and Interaction
  • T-cell and B-cell Immunology
  • IL-33, ST2, and ILC Pathways
  • CAR-T cell therapy research

Best Publications

  • The c- myc oncogene driven by immunoglobulin enhancers induces lymphoid malignancy in transgenic mice

    J. M. Adams;A. W. Harris;C. A. Pinkert;L. M. Corcoran

  • The generation of antibody-secreting plasma cells.

    Stephen L Nutt;Philip D Hodgkin;David M Tarlinton;Lynn M Corcoran

  • The POU domain: a large conserved region in the mammalian pit-1, oct-1, oct-2, and Caenorhabditis elegans unc-86 gene products

    W Herr;R A Sturm;R G Clerc;L M Corcoran

  • IL-21 regulates germinal center B cell differentiation and proliferation through a B cell-intrinsic mechanism.

    Dimitra Zotos;Jonathan M. Coquet;Yang Zhang;Amanda Light

  • Genetic analysis of the human malaria parasite plasmodium falciparum

    David Walliker;Isabella A. Quakyi;Thomas E. Wellems;Thomas F. McCutchan

  • Regulatory T-cell suppressor program co-opts transcription factor IRF4 to control T H 2 responses

    Ye Zheng;Ashutosh Chaudhry;Ashutosh Chaudhry;Arnold Kas;Paul deRoos;Paul deRoos

  • Plasma Cell Ontogeny Defined by Quantitative Changes in Blimp-1 Expression

    Axel Kallies;Jhagvaral Hasbold;David M. Tarlinton;Wendy Dietrich

  • Bcl-2 can rescue T lymphocyte development in interleukin-7 receptor-deficient mice but not in mutant rag-1-/- mice

    Eugene Maraskovsky;Lorraine A O'Reilly;Mark Teepe;Lynn M Corcoran

  • Cytokine-Mediated Regulation of Human B Cell Differentiation into Ig-Secreting Cells: Predominant Role of IL-21 Produced by CXCR5+ T Follicular Helper Cells

    Vanessa L. Bryant;Vanessa L. Bryant;Vanessa L. Bryant;Cindy S. Ma;Cindy S. Ma;Danielle T. Avery;Danielle T. Avery;Ying Li

  • Functional immunoglobulin transgenes guide ordered B-cell differentiation in Rag-1-deficient mice.

    Eugenia Spanopoulou;Christopher A. J. Roman;Lynn M. Corcoran;Mark S. Schlissel

  • The B-cell-specific Oct-2 protein contains POU box- and homeo box-type domains.

    Roger G. Clerc;Lynn M. Corcoran;Jonathan H. LeBowitz;David Baltimore

  • Class-switch recombination occurs infrequently in germinal centers

    Jonathan A. Roco;Luka Mesin;Sebastian C. Binder;Christian Nefzger

  • Transcriptional repressor Blimp-1 is essential for T cell homeostasis and self-tolerance

    Axel Kallies;Edwin D Hawkins;Gabrielle T Belz;Donald Metcalf

  • Cellular myc oncogene is altered by chromosome translocation to an immunoglobulin locus in murine plasmacytomas and is rearranged similarly in human Burkitt lymphomas

    Jerry M. Adams;Steven Gerondakis;Elizabeth Webb;Lynn M. Corcoran

  • Murine T lymphomas in which the cellular myc oncogene has been activated by retroviral insertion.

    Lynn M. Corcoran;Jerry M. Adams;Ashley R. Dunn;Suzanne Cory

  • Transcriptional profiling of mouse B cell terminal differentiation defines a signature for antibody-secreting plasma cells

    Wei Shi;Yang Liao;Simon N Willis;Nadine Taubenheim

  • Plasma cell development and survival.

    Sarah A. Oracki;Jennifer A. Walker;Margaret L. Hibbs;Lynn M. Corcoran

  • Initiation of plasma-cell differentiation is independent of the transcription factor Blimp-1.

    Axel Kallies;Jhagvaral Hasbold;Kirsten Fairfax;Kirsten Fairfax;Clare Pridans;Clare Pridans

  • Oct-2, although not required for early B-cell development, is critical for later B-cell maturation and for postnatal survival.

    Lynn M. Corcoran;Maria Karvelas;G. J. V. Nossal;Zheng-Sheng Ye

  • Virus-transformed pre-B cells show ordered activation but not inactivation of immunoglobulin gene rearrangement and transcription.

    Mark S. Schlissel;Lynn M. Corcoran;David Baltimore

Frequent Co-Authors

Stephen L. Nutt
Stephen L. Nutt Walter and Eliza Hall Institute of Medical Research
David M. Tarlinton
David M. Tarlinton Monash University
Philip D. Hodgkin
Philip D. Hodgkin Walter and Eliza Hall Institute of Medical Research
Axel Kallies
Axel Kallies University of Melbourne
Gabrielle T. Belz
Gabrielle T. Belz University of Queensland
Wei Shi
Wei Shi Monash University
Gordon K. Smyth
Gordon K. Smyth Walter and Eliza Hall Institute of Medical Research
Suzanne Cory
Suzanne Cory Walter and Eliza Hall Institute of Medical Research
Stuart G. Tangye
Stuart G. Tangye Garvan Institute of Medical Research
Li Wu
Li Wu Tsinghua University

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