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D-Index & Metrics

Molecular Biology

D-Index
95
Citations
38760
World Ranking
629
National Ranking
344

Overview

John L. Cleveland is affiliated with the Scripps Research Institute in the United States and has contributed significantly to the fields of Medicine and Biochemistry, Genetics and Molecular Biology. Their research spans several subfields including Molecular Biology, Immunology, Cancer Research, Oncology, and Hematology. The main topics of their work include Immune Cell Function and Interaction, Polyamine Metabolism and Applications, Cancer Genomics and Diagnostics, Cancer Immunotherapy and Biomarkers, Health and Medical Research Impacts, Advances in Oncology and Radiotherapy, and Acute Myeloid Leukemia Research.

Their recent publications demonstrate a focus on molecular mechanisms and cancer biology. Selected papers include:

  • Macrophage Metabolism of Apoptotic Cell-Derived Arginine Promotes Continual Efferocytosis and Resolution of Injury (2020, Cell Metabolism)
  • TP53 mutations in myelodysplastic syndromes and secondary AML confer an immunosuppressive phenotype (2020, Blood)
  • Programming inactive RNA-binding small molecules into bioactive degraders (2023, Nature)
  • Comparative Genomics Reveals Distinct Immune-oncologic Pathways in African American Men with Prostate Cancer (2020, Clinical Cancer Research)
  • Spermine oxidase mediates Helicobacter pylori-induced gastric inflammation, DNA damage, and carcinogenic signaling (2020, Oncogene)

John L. Cleveland's frequent co-authors include:

  • Anders Berglund
  • Chunying Yang
  • Rebecca S. Hesterberg
  • Seongseok Yun
  • Mario R. Fernandez

Their work is frequently published in venues such as:

  • Cancer Research
  • Blood
  • Blood Cancer Discovery
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Clinical Cancer Research

Best Publications

  • Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes

    Daniel J. Klionsky;Hagai Abeliovich;Patrizia Agostinis;Devendra K. Agrawal

  • Myc signaling via the ARF tumor suppressor regulates p53-dependent apoptosis and immortalization

    Frederique Zindy;Christine M. Eischen;David H. Randle;Takehiko Kamijo

  • Toll-like receptor signalling in macrophages links the autophagy pathway to phagocytosis

    Miguel A. Sanjuan;Christopher P. Dillon;Stephen W. G. Tait;Simon Moshiach

  • Constitutive c-myc expression in an IL-3-dependent myeloid cell line suppresses cell cycle arrest and accelerates apoptosis.

    D S Askew;R A Ashmun;B C Simmons;J L Cleveland

  • Targeting lactate metabolism for cancer therapeutics

    Joanne R. Doherty;John L. Cleveland

  • Puma is an essential mediator of p53-dependent and -independent apoptotic pathways

    John R. Jeffers;Evan Parganas;Evan Parganas;Youngsoo Lee;Chunying Yang

  • Disruption of the ARF–Mdm2–p53 tumor suppressor pathway in Myc-induced lymphomagenesis

    Christine M. Eischen;Jason D. Weber;Martine F. Roussel;Charles J. Sherr

  • The ornithine decarboxylase gene is a transcriptional target of c-Myc.

    Concha Bello-Fernandez;Graham Packham;John L. Cleveland

  • NIX is required for programmed mitochondrial clearance during reticulocyte maturation

    Rachel L. Schweers;Ji Zhang;Mindy S. Randall;Melanie R. Loyd

  • Phosphorylation-dependent regulation of cyclin D1 nuclear export and cyclin D1–dependent cellular transformation

    Jodi R. Alt;John L. Cleveland;Mark Hannink;J. Alan Diehl

  • Structure of the murine Jak2 protein-tyrosine kinase and its role in interleukin 3 signal transduction.

    Olli Silvennoinen;Bruce A. Witthuhn;Frederick W. Quelle;John L. Cleveland

  • Myc pathways provoking cell suicide and cancer

    Jonas A Nilsson;John L Cleveland

  • c-Myc is essential for vasculogenesis and angiogenesis during development and tumor progression

    Troy A. Baudino;Catriona McKay;Helene Pendeville-Samain;Jonas A. Nilsson

  • Systems analysis of intracellular pH vulnerabilities for cancer therapy.

    Erez Persi;Erez Persi;Miquel Duran-Frigola;Mehdi Damaghi;William R. Roush

  • Evasion of the p53 tumour surveillance network by tumour-derived MYC mutants

    Michael T. Hemann;Anka Bric;Julie Teruya-Feldstein;Andreas Herbst

  • Phospholipase Cγ2 Is Essential in the Functions of B Cell and Several Fc Receptors

    Demin Wang;Jian Feng;Jian Feng;Renren Wen;Jean-Christophe Marine

  • Protein tyrosine phosphatase containing SH2 domains: characterization, preferential expression in hematopoietic cells, and localization to human chromosome 12p12-p13.

    Taolin Yi;J. L. Cleveland;J. N. Ihle

  • Mitochondrial dysfunction in ataxia-telangiectasia.

    Yasmine A. Valentin-Vega;Kirsteen H. MacLean;Jacqueline Tait-Mulder;Sandra Milasta

  • Contenders in FasL/TNF death signaling

    John L. Cleveland;James N. Ihle;James N. Ihle

  • Cloning of murine Stat6 and human Stat6, Stat proteins that are tyrosine phosphorylated in responses to IL-4 and IL-3 but are not required for mitogenesis.

    F W Quelle;K Shimoda;W Thierfelder;C Fischer

Frequent Co-Authors

James N. Ihle
James N. Ihle St. Jude Children's Research Hospital
Jonas A. Nilsson
Jonas A. Nilsson University of Gothenburg
Ulf R. Rapp
Ulf R. Rapp Max Planck Society
Graham Packham
Graham Packham University of Southampton
William R. Roush
William R. Roush Scripps Research Institute
Martine F. Roussel
Martine F. Roussel St. Jude Children's Research Hospital
Gerard P. Zambetti
Gerard P. Zambetti St. Jude Children's Research Hospital
Mahmoud Huleihel
Mahmoud Huleihel Ben-Gurion University of the Negev
Mark A. Hall
Mark A. Hall Wake Forest University
Scott W. Hiebert
Scott W. Hiebert Vanderbilt University

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