World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
72
Citations
25882
World Ranking
6158
National Ranking
2896

Overview

Gerard P. Zambetti is affiliated with St. Jude Children's Research Hospital in the United States. Their research primarily focuses on the fields of Biochemistry, Genetics and Molecular Biology, and Medicine, with 34 and 27 publications respectively.

The scientist's work extensively covers subfields such as Molecular Biology, Oncology, Cancer Research, Genetics, and Surgery. Key topics addressed include Cancer-related Molecular Pathways, Cancer, Hypoxia, and Metabolism, Epigenetics and DNA Methylation, Adrenal and Paraganglionic Tumors, Cancer Genomics and Diagnostics, Renal and related cancers, and Glioma Diagnosis and Treatment.

Zambetti's recent notable publications are as follows:

  • Treatment of Pediatric Adrenocortical Carcinoma With Surgery, Retroperitoneal Lymph Node Dissection, and Chemotherapy: The Children's Oncology Group ARAR0332 Protocol (2021) in Journal of Clinical Oncology
  • Pediatric adrenocortical tumours (2020) in Best Practice & Research Clinical Endocrinology & Metabolism
  • XAF1 as a modifier of p53 function and cancer susceptibility (2020) in Science Advances
  • What 20 years of research has taught us about the TP53 p.R337H mutation (2020) in Cancer
  • A Rare TP53 Mutation Predominant in Ashkenazi Jews Confers Risk of Multiple Cancers (2020) in Cancer Research

Frequent co-authors include:

  • Emília M. Pinto (23 co-authored publications)
  • Raul C. Ribeiro (13 co-authored publications)
  • Carlos Rodríguez-Galindo (8 co-authored publications)
  • Bonald C. Figueiredo (8 co-authored publications)
  • Michael R. Clay (7 co-authored publications)

Zambetti's publications have appeared frequently in venues such as Cancer Research, Cancers, Journal of the Endocrine Society, Journal of Clinical Oncology, and Science Advances, with counts of three, three, two, one, and one publication(s) respectively.

Best Publications

  • Functional and physical interactions of the ARF tumor suppressor with p53 and Mdm2

    Takehiko Kamijo;Jason D. Weber;Gerard Zambetti;Frederique Zindy

  • Puma is an essential mediator of p53-dependent and -independent apoptotic pathways

    John R. Jeffers;Evan Parganas;Evan Parganas;Youngsoo Lee;Chunying Yang

  • Hierarchical regulation of mitochondrion-dependent apoptosis by BCL-2 subfamilies.

    Hyungjin Kim;Mubina Rafiuddin-Shah;Ho-Chou Tu;John R. Jeffers

  • Stepwise Activation of BAX and BAK by tBID, BIM, and PUMA Initiates Mitochondrial Apoptosis

    Hyungjin Kim;Ho-Chou Tu;Decheng Ren;Osamu Takeuchi

  • An inherited p53 mutation that contributes in a tissue-specific manner to pediatric adrenal cortical carcinoma

    Raul C. Ribeiro;Fabiano Sandrini;Bonald Figueiredo;Gerard P. Zambetti

  • Expression of bbc3, a pro-apoptotic BH3-only gene, is regulated by diverse cell death and survival signals.

    Jia-wen Han;Cathy Flemington;Anne B. Houghton;Zhengming Gu

  • BID, BIM, and PUMA Are Essential for Activation of the BAX- and BAK-Dependent Cell Death Program

    Decheng Ren;Ho Chou Tu;Hyungjin Kim;Gary X. Wang

  • Slug Antagonizes p53-Mediated Apoptosis of Hematopoietic Progenitors by Repressing puma

    Wen Shu Wu;Stefan Heinrichs;Dong Xu;Sean P. Garrison

  • The landscape of somatic mutations in epigenetic regulators across 1,000 paediatric cancer genomes

    Robert Huether;Li Dong;Xiang Chen;Gang Wu

  • A novel mechanism of tumorigenesis involving pH-dependent destabilization of a mutant p53 tetramer

    Enrico L DiGiammarino;Amanda S Lee;Craig Cadwell;Weixing Zhang

  • The effects of wild-type p53 tumor suppressor activity and mutant p53 gain-of-function on cell growth.

    Craig Cadwell;Gerard P Zambetti

  • Mutant p53 cooperates with ETS and selectively up-regulates human MDR1 not MRP1.

    Janardhan Sampath;Daxi Sun;Vincent J. Kidd;Jose Grenet

  • Activation of c-myc Gene Expression by Tumor-Derived p53 Mutants Requires a Discrete C-Terminal Domain

    Mark W. Frazier;Xiaoping He;JinLing Wang;Zhengming Gu

  • Regulation of Insulin-like Growth Factor-Mammalian Target of Rapamycin Signaling by MicroRNA in Childhood Adrenocortical Tumors

    Mabrouka Doghman;Abeer El Wakil;Bruno Cardinaud;Emilie Thomas

  • PUMA Regulates Intestinal Progenitor Cell Radiosensitivity and Gastrointestinal Syndrome

    Wei Qiu;Eleanor B. Carson-Walter;Hongtao Liu;Michael Epperly

  • Increased Steroidogenic Factor-1 dosage triggers adrenocortical cell proliferation and cancer.

    Mabrouka Doghman;Tatiana Karpova;Giovanna Assis Rodrigues;Malika Arhatte

  • Clinical and Molecular Characteristics of Malignant Transformation of Low-Grade Glioma in Children

    Alberto Broniscer;Suzanne J. Baker;Alina N. West;Melissa M. Fraser

  • Mdm‐2: “big brother” of p53

    Jamil Momand;Gerard P. Zambetti

  • p53-dependent regulation of MDR1 gene expression causes selective resistance to chemotherapeutic agents

    Jaideep V. Thottassery;Gerard P. Zambetti;Kazuhiko Arimori;Erin G. Schuetz

  • E2F-1:DP-1 induces p53 and overrides survival factors to trigger apoptosis.

    S W Hiebert;G Packham;D K Strom;R Haffner

Frequent Co-Authors

Raul C. Ribeiro
Raul C. Ribeiro St. Jude Children's Research Hospital
Enzo Lalli
Enzo Lalli Centre national de la recherche scientifique, CNRS
Alberto S. Pappo
Alberto S. Pappo St. Jude Children's Research Hospital
Stanley Pounds
Stanley Pounds St. Jude Children's Research Hospital
John L. Cleveland
John L. Cleveland Moffitt Cancer Center
Carlos Rodriguez-Galindo
Carlos Rodriguez-Galindo St. Jude Children's Research Hospital
Geoffrey Neale
Geoffrey Neale St. Jude Children's Research Hospital
Jinghui Zhang
Jinghui Zhang St. Jude Children's Research Hospital
Elaine R. Mardis
Elaine R. Mardis The Ohio State University
Gang Wu
Gang Wu Washington University in St. Louis

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

If you’re passionate about Biology and Biochemistry, there are several related online degrees that can help launch or advance your career in health and life sciences. For those interested in the science of nutrition, exploring the best online nutrition programs is a great starting point. These programs offer foundational knowledge in biochemistry and its applications to diet, wellness, and public health.

Moving into healthcare leadership, consider cahme accredited online mha programs to gain skills in managing hospitals and health organizations. These programs blend science, business, and policy, ideal for those looking to make a broader impact.

For advanced practice nurses eyeing the next step, online dnp programs provide leadership, research, and clinical expertise without the need for on-site practicums. Meanwhile, professionals wishing to drive healthcare innovation and administration can look to the best online dha programs for a doctorate in healthcare management.

These pathways build on your Biology or Biochemistry background and open doors to a variety of rewarding roles in science, healthcare, and management.

Best Scientists Citing Gerard P. Zambetti

Trending Scientists