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Biology and Biochemistry

D-Index
59
Citations
10117
World Ranking
12779
National Ranking
995

Overview

John E. G. McCarthy is affiliated with the University of Warwick in the United Kingdom. Their research primarily focuses on the field of Biochemistry, Genetics and Molecular Biology, with particular concentration in Molecular Biology, Genetics, Aging, and Physiology. The scope of their work encompasses several specialized topics including Gene Regulatory Network Analysis, Mitochondrial Function and Pathology, Genetics, Aging, and Longevity in Model Organisms, Viral Infectious Diseases and Gene Expression in Insects, Fungal and Yeast Genetics Research, DNA Repair Mechanisms, and Photosynthetic Processes and Mechanisms.

They have contributed to a range of recent scientific papers, including:

  • Stochastic scanning events on the GCN4 mRNA 5' untranslated region generate cell-to-cell heterogeneity in the yeast nutritional stress response, 2023, Nucleic Acids Research
  • Translational control of gene expression noise and its relationship to ageing in yeast, 2020, FEBS Journal
  • Protecting double Holliday junctions ensures crossing over during meiosis, 2025, Nature
  • Paternal mitochondria from an rmd-2, rmd-3, rmd-6 triple mutant are properly positioned in the C. elegans zygote, 2021, PubMed
  • Engineering and standardization of posttranscriptional biocircuitry inSaccharomyces cerevisiae, 2021, Integrative Biology

Their frequent coauthors include Xiang Meng, Alan Reed, Sandie Lai, Juraj Szavits-Nossan, and Shangming Tang.

John E. G. McCarthy's research outputs have appeared in multiple scientific journals such as Nucleic Acids Research, Nature, FEBS Journal, PubMed, and Integrative Biology.

Best Publications

  • VEGF and VEGF-C: Specific Induction of Angiogenesis and Lymphangiogenesis in the Differentiated Avian Chorioallantoic Membrane

    Su Ja Oh;Markku M. Jeltsch;Ralf Birkenhäger;John E.G. McCarthy

  • Ribosome Loading onto the mRNA Cap Is Driven by Conformational Coupling between eIF4G and eIF4E

    John D. Gross;Nathan J. Moerke;Tobias von der Haar;Alexey A. Lugovskoy

  • Posttranscriptional Control of Gene Expression in Yeast

    John E. G. McCarthy

  • Inducible expression vectors incorporating the Escherichia coli atpE translational initiation region.

    Birgit Schauder;Helmut Blöcker;Ronald Frank;John E.G. McCarthy

  • Probing the presumed catalytic triad of selenium-containing peroxidases by mutational analysis of phospholipid hydroperoxide glutathione peroxidase (PHGPx).

    Maiorino M;Aumann Kd;Brigelius-Flohé R;Doria D

  • The mRNA cap-binding protein eIF4E in post-transcriptional gene expression.

    Tobias von der Haar;John D Gross;Gerhard Wagner;John E G McCarthy

  • Proteins binding to 5' untranslated region sites: a general mechanism for translational regulation of mRNAs in human and yeast cells.

    R. Stripecke;C. C. Oliveira;J. E. G. Mccarthy;M. W. Hentze

  • Dynamics and processivity of 40S ribosome scanning on mRNA in yeast

    Karine Berthelot;Mark Muldoon;Lukas Rajkowitsch;John Hughes

  • VEGF121 induces proliferation of vascular endothelial cells and expression of flk-1 without affecting lymphatic vessels of chorioallantoic membrane.

    Jörg Wilting;Ralf Birkenhäger;Anne Eichmann;Haymo Kurz

  • Cytoplasmic mRNA-protein interactions in eukaryotic gene expression.

    John E.G. McCarthy;Heike Kollmus

  • Inhibition of translational initiation in the yeast Saccharomyces cerevisiae as a function of the stability and position of hairpin structures in the mRNA leader.

    M R Vega Laso;D Zhu;F Sagliocco;A J Brown

  • Stabilization of eukaryotic initiation factor 4E binding to the mRNA 5'-Cap by domains of eIF4G

    Tobias von der Haar;Philip D. Ball;John E.G. McCarthy

  • Reengineering orthogonally selective riboswitches

    Neil Dixon;John N. Duncan;Torsten Geerlings;Mark S. Dunstan

  • The relationship between eukaryotic translation and mRNA stability. A short upstream open reading frame strongly inhibits translational initiation and greatly accelerates mRNA degradation in the yeast Saccharomyces cerevisiae.

    Carla C. Oliveira;John E.G. McCarthy

  • A model of yeast glycolysis based on a consistent kinetic characterisation of all its enzymes.

    Kieran Smallbone;Hanan L. Messiha;Kathleen M. Carroll;Catherine L. Winder

  • Translation initiation: variations in the mechanism can be anticipated

    Naglis Malys;John E. G. McCarthy

  • The yeast transcription factor genes YAP1 and YAP2 are subject to differential control at the levels of both translation and mRNA stability

    Cristina Vilela;Bodo Linz;Claudina Rodrigues-Pousada;John E. G. McCarthy

  • Tetracycline-aptamer-mediated translational regulation in yeast

    Shane Hanson;Karine Berthelot;Barbara Fink;John E. G. McCarthy

  • Analysis of Eukaryotic mRNA Structures Directing Cotranslational Incorporation of Selenocysteine

    Heike Kollmus;Leopold Flohé;John E.G. McCarthy

  • Inhibition of translational initiation in Saccharomyces cerevisiae by secondary structure: the roles of the stability and position of stem‐loops in the mRNA leader

    Caria C. Oliveira;Joop J. van den Heuvel;John E. G. McCarthy

Frequent Co-Authors

Mick F. Tuite
Mick F. Tuite University of Kent
Pedro Mendes
Pedro Mendes University of Connecticut
Hans V. Westerhoff
Hans V. Westerhoff Vrije Universiteit Amsterdam
Alistair J. P. Brown
Alistair J. P. Brown University of Exeter
Gerhard Wagner
Gerhard Wagner Harvard University
Jörg Wilting
Jörg Wilting University of Göttingen
Simon J. Gaskell
Simon J. Gaskell Plymouth University
Stephen G. Oliver
Stephen G. Oliver University of Cambridge
Alexander D. Cameron
Alexander D. Cameron University of Warwick
Patrick Linder
Patrick Linder University of Geneva

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