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Alexander D. Cameron

Alexander D. Cameron

D-Index & Metrics

Chemistry

D-Index
42
Citations
8503
World Ranking
17405
National Ranking
950

Overview

Alexander D. Cameron is affiliated with the University of Warwick in the United Kingdom. Their research spans the fields of Biochemistry, Genetics and Molecular Biology, and Medicine, with a notable focus on molecular biology, oncology, epidemiology, inorganic chemistry, and genetics.

The scientific work of Alexander D. Cameron covers a range of specialized topics, including:

  • Drug Transport and Resistance Mechanisms
  • Connexins and lens biology
  • Heat shock proteins research
  • Metal-Catalyzed Oxygenation Mechanisms
  • Nicotinic Acetylcholine Receptors Study
  • Trace Elements in Health
  • Autophagy in Disease and Therapy

Their recent peer-reviewed publications include:

  • Conformational changes and CO2-induced channel gating in connexin26, 2022, published in Structure
  • Regulation of Expression of Autophagy Genes by Atg8a-Interacting Partners Sequoia, YL-1, and Sir2 in Drosophila, 2020, published in Cell Reports
  • Structural basis of carnitine monooxygenase CntA substrate specificity, inhibition, and intersubunit electron transfer, 2020, published in Journal of Biological Chemistry
  • Structural basis of trehalose recognition by the mycobacterial LpqY-SugABC transporter, 2021, published in Journal of Biological Chemistry
  • Light-Activated Electron Transfer and Catalytic Mechanism of Carnitine Oxidation by Rieske-Type Oxygenase from Human Microbiota, 2020, published in Angewandte Chemie International Edition

Frequent collaborators in their research endeavors include:

  • Deborah H. Brotherton
  • Nicholas Dale
  • Christos G. Savva
  • Mussa Quareshy
  • Muralidharan Shanmugam

Alexander D. Cameron's work is often published in the following venues:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • eLife
  • Biophysical Journal
  • Journal of Biological Chemistry
  • Structure

Best Publications

  • Overcoming the challenges of membrane protein crystallography.

    Elisabeth P Carpenter;Konstantinos Beis;Alexander D Cameron;So Iwata;So Iwata

  • Structure and Molecular Mechanism of a Nucleobase-Cation-Symport-1 Family Transporter

    Simone Weyand;Tatsuro Shimamura;Tatsuro Shimamura;Shunsuke Yajima;Shun'ichi Suzuki

  • G-protein-coupled receptor inactivation by an allosteric inverse-agonist antibody

    Tomoya Hino;Takatoshi Arakawa;Hiroko Iwanari;Takami Yurugi-Kobayashi

  • Crystal structure of a prokaryotic homologue of the mammalian oligopeptide–proton symporters, PepT1 and PepT2

    Simon Newstead;David Drew;Alexander D Cameron;Vincent L G Postis

  • Molecular Basis of Alternating Access Membrane Transport by the Sodium-Hydantoin Transporter Mhp1

    Tatsuro Shimamura;Tatsuro Shimamura;Simone Weyand;Oliver Beckstein;Nicholas G. Rutherford

  • Crystal structure of a bacterial homologue of the bile acid sodium symporter ASBT.

    Nien-Jen Hu;So Iwata;Alexander D. Cameron;David Drew

  • Crystal structure of human glyoxalase I—evidence for gene duplication and 3D domain swapping

    A D Cameron;B Olin;M Ridderström;B Mannervik

  • A two-domain elevator mechanism for sodium/proton antiport

    Chiara Lee;Hae Joo Kang;Christoph von Ballmoos;Simon Newstead

  • Alternating access mechanism in the POT family of oligopeptide transporters

    Nicolae Solcan;Jane Kwok;Philip W Fowler;Alexander D Cameron;Alexander D Cameron

  • Crystal structure of the anion exchanger domain of human erythrocyte band 3

    Takatoshi Arakawa;Takami Kobayashi-Yurugi;Yilmaz Alguel;Hiroko Iwanari

  • Clustering procedures for the optimal selection of data sets from multiple crystals in macromolecular crystallography

    James Foadi;Pierre Aller;Yilmaz Alguel;Alexander Cameron

  • 1,4,5,6-Tetrahydropyrrolo[3,4-C]Pyrazoles: Identification of a Potent Aurora Kinase Inhibitor with a Favorable Antitumor Kinase Inhibition Profile.

    Daniele Fancelli;Jürgen Moll;Mario Varasi;Rodrigo Bravo

  • Crystal structure of human glyoxalase II and its complex with a glutathione thiolester substrate analogue.

    Alexander D Cameron;Marianne Ridderström;Birgit Olin;Bengt Mannervik

  • Structure of Escherichia coli ribokinase in complex with ribose and dinucleotide determined to 1.8 A resolution: insights into a new family of kinase structures.

    JA Sigrell;AD Cameron;TA Jones;SL Mowbray

  • Structural analysis of human alpha-class glutathione transferase A1-1 in the apo-form and in complexes with ethacrynic acid and its glutathione conjugate.

    A.D Cameron;I Sinning;G L'Hermite;B Olin

  • 3-Aminopyrazole Inhibitors of CDK2/Cyclin A as Antitumor Agents. 1. Lead Finding

    Paolo Pevarello;Maria Gabriella Brasca;Raffaella Amici;Paolo Orsini

  • Crystal structure of glucansucrase from the dental caries pathogen Streptococcus mutans.

    Keisuke Ito;Sohei Ito;Tatsuro Shimamura;Simone Weyand

  • Benchmarking Membrane Protein Detergent Stability for Improving Throughput of High-Resolution X-ray Structures

    Yo Sonoda;Simon Newstead;Nien-Jen Hu;Yilmaz Alguel

  • Crystal structure of the T315I Abl mutant in complex with the aurora kinases inhibitor PHA-739358

    Michele Modugno;Elena Casale;Chiara Soncini;Pamela Rosettani

  • Potent and selective Aurora inhibitors identified by the expansion of a novel scaffold for protein kinase inhibition.

    Daniele Fancelli;Daniela Berta;Simona Bindi;Alexander Cameron

  • Clustering procedures for the optimal selection of data sets from multiple crystals in macromolecular crystallography

    J. Foadi;P. Aller;D. Axford;R. Owen

  • A two-domain elevator mechanism for sodium/proton antiport

    C. Lee;H.J. Kang;C. von Ballmoos;S. Newstead

Frequent Co-Authors

So Iwata
So Iwata Kyoto University
Peter J. F. Henderson
Peter J. F. Henderson University of Leeds
T.A. Jones
T.A. Jones Uppsala University
Mark S.P. Sansom
Mark S.P. Sansom University of Oxford
Bengt Mannervik
Bengt Mannervik Stockholm University
Alexandra M. E. Jones
Alexandra M. E. Jones University of Warwick
Sherry L. Mowbray
Sherry L. Mowbray Uppsala University
Timothy D. H. Bugg
Timothy D. H. Bugg University of Warwick
Terje Johansen
Terje Johansen University of Tromsø - The Arctic University of Norway
John E. G. McCarthy
John E. G. McCarthy University of Warwick

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