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Neuroscience

D-Index
49
Citations
9584
World Ranking
5953
National Ranking
92

Overview

Angel Barco is affiliated with the Instituto de Neurociencias de Alicante in Spain. Their research spans multiple areas within biochemistry, genetics, and molecular biology, focusing primarily on molecular biology, genetics, and cellular and molecular neuroscience.

Their work explores various research topics including:

  • Genetics and neurodevelopmental disorders
  • Epigenetics and DNA methylation
  • Genomics and chromatin dynamics
  • RNA research and splicing
  • Neuroinflammation and neurodegeneration mechanisms
  • MicroRNA in disease regulation
  • Single-cell and spatial transcriptomics

Barco's publication record includes papers in high-profile journals and venues such as Nature Communications, Cell Reports, Science Advances, Neuroscience & Biobehavioral Reviews, and Advanced Science. Some recent papers with year and publication venue are:

  • KAT3-dependent acetylation of cell type-specific genes maintains neuronal identity in the adult mouse brain, 2020, Nature Communications
  • Sublayer- and cell-type-specific neurodegenerative transcriptional trajectories in hippocampal sclerosis, 2021, Cell Reports
  • A Zic2-regulated switch in a noncanonical Wnt/βcatenin pathway is essential for the formation of bilateral circuits, 2020, Science Advances
  • Transcriptome and epigenome analysis of engram cells: Next-generation sequencing technologies in memory research, 2021, Neuroscience & Biobehavioral Reviews
  • Multiomic Analysis of Neurons with Divergent Projection Patterns Identifies Novel Regulators of Axon Pathfinding, 2022, Advanced Science

Frequent coauthors in their publications include:

  • Sergio Niñerola
  • Beatriz del Blanco
  • José P. López-Atalaya
  • Miguel Fuentes-Ramos
  • Rafael Muñoz-Viana

Barco has contributed significantly to publication venues such as bioRxiv (Cold Spring Harbor Laboratory) with four publications, Nature Communications with three, Cell Reports with two, Science Advances, and Neuroscience & Biobehavioral Reviews with one publication each.

Best Publications

  • Chromatin acetylation, memory, and LTP are impaired in CBP+/- mice: a model for the cognitive deficit in Rubinstein-Taybi syndrome and its amelioration.

    Juan M Alarcón;Gaël Malleret;Khalid Touzani;Svetlana Vronskaya

  • Expression of constitutively active CREB protein facilitates the late phase of long-term potentiation by enhancing synaptic capture.

    Angel Barco;Juan M. Alarcon;Eric R. Kandel;Eric R. Kandel

  • CREB's control of intrinsic and synaptic plasticity: implications for CREB-dependent memory models

    Eva Benito;Angel Barco

  • Activated CREB Is Sufficient to Overcome Inhibitors in Myelin and Promote Spinal Axon Regeneration In Vivo

    Ying Gao;Kangwen Deng;Jianwei Hou;J.Barney Bryson

  • Gene expression profiling of facilitated L-LTP in VP16-CREB mice reveals that BDNF is critical for the maintenance of LTP and its synaptic capture

    Angel Barco;Angel Barco;Susan L. Patterson;Susan L. Patterson;Juan M. Alarcon;Petra Gromova

  • Common molecular mechanisms in explicit and implicit memory.

    Angel Barco;Craig H. Bailey;Eric R. Kandel;Eric R. Kandel

  • CREB-binding protein controls response to cocaine by acetylating histones at the fosB promoter in the mouse striatum

    Amir A. Levine;Zhonghui Guan;Angel Barco;Shiqin Xu

  • Transient expansion of synaptically connected dendritic spines upon induction of hippocampal long-term potentiation

    Cynthia Lang;Angel Barco;Leonard Zablow;Eric R. Kandel

  • CREB, memory enhancement and the treatment of memory disorders: promises, pitfalls and prospects

    Angel Barco;Christopher Pittenger;Eric R Kandel

  • cAMP response element-binding protein-mediated gene expression increases the intrinsic excitability of CA1 pyramidal neurons.

    Mikel Lopez de Armentia;Dragana Jancic;Roman Olivares;Juan M. Alarcon

  • Membrane Permeabilization by Poliovirus Proteins 2B and 2BC

    Rafael Aldabe;Angel Barco;Luis Carrasco

  • Lysine Acetyltransferases CBP and p300 as Therapeutic Targets in Cognitive and Neurodegenerative Disorders

    Luis M. Valor;Jose Viosca;Jose P. Lopez-Atalaya;Angel Barco

  • Poliovirus protease 3C(pro) kills cells by apoptosis.

    Angel Barco;Elena Feduchi;Luis Carrasco

  • Immediate and deferred epigenomic signatures of in vivo neuronal activation in mouse hippocampus.

    Jordi Fernandez-Albert;Michal Lipinski;María T. Lopez-Cascales;M. Jordan Rowley;M. Jordan Rowley

  • A semi-persistent adult ocular dominance plasticity in visual cortex is stabilized by activated CREB.

    Tony A. Pham;Sarah J. Graham;Seigo Suzuki;Angel Barco

  • Genetic Approaches to Investigate the Role of CREB in Neuronal Plasticity and Memory

    Angel Barco;Hélène Marie

  • Selective boosting of transcriptional and behavioral responses to drugs of abuse by histone deacetylase inhibition.

    Carles Sanchis-Segura;Jose P Lopez-Atalaya;Angel Barco

  • The Neuronal Activity-Driven Transcriptome

    Eva Benito;Angel Barco

  • Ablation of CBP in Forebrain Principal Neurons Causes Modest Memory and Transcriptional Defects and a Dramatic Reduction of Histone Acetylation But Does Not Affect Cell Viability

    Luis Miguel Valor;Matias M. Pulopulos;María Jiménez-Minchan;Román Olivares

  • Epigenetic Etiology of Intellectual Disability

    Shigeki Iwase;Nathalie G. Bérubé;Zhaolan Zhou;Nael Nadif Kasri

  • Enhanced CREB-dependent gene expression increases the excitability of neurons in the basal amygdala and primes the consolidation of contextual and cued fear memory

    Jose Viosca;Mikel Lopez de Armentia;Dragana Jancic;Angel Barco

  • cAMP Response Element-Binding Protein Is a Primary Hub of Activity-Driven Neuronal Gene Expression

    Eva Benito;Luis Miguel Valor;María Jiménez-Minchan;Wolfgang Huber

Frequent Co-Authors

Eric R. Kandel
Eric R. Kandel Columbia University
Luis Carrasco
Luis Carrasco Centro de Biología Molecular Severo Ochoa
Santiago Canals
Santiago Canals Spanish National Research Council
Fabrizio Gardoni
Fabrizio Gardoni University of Milan
Elena Galea
Elena Galea Autonomous University of Barcelona
Pierre Paoletti
Pierre Paoletti École Normale Supérieure
Liset Menendez de la Prida
Liset Menendez de la Prida Spanish National Research Council
Vance Lemmon
Vance Lemmon University of Miami
Victor G. Corces
Victor G. Corces Emory University
Lidia Larizza
Lidia Larizza University of Milan

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