Schahram Akbarian focuses on Neuroscience, Genetics, Cerebral cortex, Prefrontal cortex and Regulation of gene expression. His research in Neuroscience intersects with topics in Schizophrenia, Histone and DNA methylation. His biological study spans a wide range of topics, including Neurodegeneration and Cell biology.
As part of his Internal medicine and Endocrinology and Cerebral cortex studies, Schahram Akbarian is studying Cerebral cortex. His Regulation of gene expression study contributes to a more complete understanding of Gene. He combines subjects such as Mutation and Null allele with his study of MECP2.
His primary areas of study are Neuroscience, Epigenetics, Genetics, Chromatin and Prefrontal cortex. His Neuroscience study integrates concerns from other disciplines, such as Schizophrenia, Psychosis and Disease. His Epigenetics research is multidisciplinary, relying on both Epigenomics, Histone methylation, DNA methylation, Epigenome and H3K4me3.
Schahram Akbarian interconnects Enhancer, Chromosome conformation capture, Histone and Cell biology in the investigation of issues within Chromatin. The study incorporates disciplines such as Cerebral cortex, Endocrinology, Internal medicine, Gene expression and Autism in addition to Prefrontal cortex. His Regulation of gene expression research includes elements of MECP2, microRNA and Rett syndrome.
His primary areas of investigation include Neuroscience, Computational biology, Epigenetics, Chromatin and Gene. Schahram Akbarian is interested in Prefrontal cortex, which is a field of Neuroscience. His Computational biology study also includes
His studies deal with areas such as Schizophrenia, Histone and Human brain as well as Epigenetics. His study on Histone is covered under Genetics. His Chromatin study incorporates themes from Enhancer, Transcriptome and Neocortex.
His main research concerns Neuroscience, Chromatin, Gene, Epigenetics and Prefrontal cortex. His Neuroscience research is multidisciplinary, incorporating elements of Haploinsufficiency and Gene knockdown. Schahram Akbarian has included themes like Regulation of gene expression, Genome, Repressor and Epigenome in his Chromatin study.
His Gene research is multidisciplinary, incorporating perspectives in Dopaminergic, Psychosis, Cell type and Human brain. Epigenetics is a subfield of Genetics that he explores. His study in Prefrontal cortex is interdisciplinary in nature, drawing from both Juvenile, Autism, Optogenetics, Social isolation and Metabolome.
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Deficiency of methyl-CpG binding protein-2 in CNS neurons results in a Rett-like phenotype in mice
Richard Z. Chen;Schahram Akbarian;Schahram Akbarian;Matthew Tudor;Rudolf Jaenisch.
Nature Genetics (2001)
Gene expression for glutamic acid decarboxylase is reduced without loss of neurons in prefrontal cortex of schizophrenics.
Schahram Akbarian;James J. Kim;Steven G. Potkin;Jennifer O. Hagman.
Archives of General Psychiatry (1995)
Altered Distribution of Nicotinamide-Adenine Dinucleotide Phosphate—Diaphorase Cells in Frontal Lobe of Schizophrenics Implies Disturbances of Cortical Development
Schahram Akbarian;William E. Bunney;Steven G. Potkin;Sharon B. Wigal.
Archives of General Psychiatry (1993)
Distorted distribution of nicotinamide-adenine dinucleotide phosphate-diaphorase neurons in temporal lobe of schizophrenics implies anomalous cortical development.
Schahram Akbarian;Angel Viñuela;James J. Kim;Steven G. Potkin.
Archives of General Psychiatry (1993)
Selective alterations in gene expression for NMDA receptor subunits in prefrontal cortex of schizophrenics
S Akbarian;NJ Sucher;D Bradley;A Tafazzoli.
The Journal of Neuroscience (1996)
Developmental and regional expression pattern of a novel NMDA receptor- like subunit (NMDAR-L) in the rodent brain
NJ Sucher;S Akbarian;CL Chi;CL Leclerc.
The Journal of Neuroscience (1995)
Maldistribution of Interstitial Neurons in Prefrontal White Matter of the Brains of Schizophrenic Patients
Schahram Akbarian;James J. Kim;Steven G. Pothin;William P. Hetrick.
Archives of General Psychiatry (1996)
Antidepressant-like effects of the histone deacetylase inhibitor, sodium butyrate, in the mouse
Frederick Albert Schroeder;Cong L. Lin;Wim E. Crusio;Schahram Akbarian.
Biological Psychiatry (2007)
DNA Methylation in the Human Cerebral Cortex Is Dynamically Regulated throughout the Life Span and Involves Differentiated Neurons
Kimberly D. Siegmund;Caroline M. Connor;Mihaela Campan;Tiffany I. Long.
PLOS ONE (2007)
Epigenetic mechanisms in neurological disease
Mira Jakovcevski;Schahram Akbarian.
Nature Medicine (2012)
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