D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 57 Citations 12,315 121 World Ranking 6397 National Ranking 2971

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • DNA
  • Genetics

Schahram Akbarian focuses on Neuroscience, Genetics, Cerebral cortex, Prefrontal cortex and Regulation of gene expression. His research in Neuroscience intersects with topics in Schizophrenia, Histone and DNA methylation. His biological study spans a wide range of topics, including Neurodegeneration and Cell biology.

As part of his Internal medicine and Endocrinology and Cerebral cortex studies, Schahram Akbarian is studying Cerebral cortex. His Regulation of gene expression study contributes to a more complete understanding of Gene. He combines subjects such as Mutation and Null allele with his study of MECP2.

His most cited work include:

  • Deficiency of methyl-CpG binding protein-2 in CNS neurons results in a Rett-like phenotype in mice (1046 citations)
  • Deficiency of methyl-CpG binding protein-2 in CNS neurons results in a Rett-like phenotype in mice (1046 citations)
  • Gene expression for glutamic acid decarboxylase is reduced without loss of neurons in prefrontal cortex of schizophrenics. (866 citations)

What are the main themes of his work throughout his whole career to date?

His primary areas of study are Neuroscience, Epigenetics, Genetics, Chromatin and Prefrontal cortex. His Neuroscience study integrates concerns from other disciplines, such as Schizophrenia, Psychosis and Disease. His Epigenetics research is multidisciplinary, relying on both Epigenomics, Histone methylation, DNA methylation, Epigenome and H3K4me3.

Schahram Akbarian interconnects Enhancer, Chromosome conformation capture, Histone and Cell biology in the investigation of issues within Chromatin. The study incorporates disciplines such as Cerebral cortex, Endocrinology, Internal medicine, Gene expression and Autism in addition to Prefrontal cortex. His Regulation of gene expression research includes elements of MECP2, microRNA and Rett syndrome.

He most often published in these fields:

  • Neuroscience (45.80%)
  • Epigenetics (36.13%)
  • Genetics (34.87%)

What were the highlights of his more recent work (between 2018-2021)?

  • Neuroscience (45.80%)
  • Computational biology (9.24%)
  • Epigenetics (36.13%)

In recent papers he was focusing on the following fields of study:

His primary areas of investigation include Neuroscience, Computational biology, Epigenetics, Chromatin and Gene. Schahram Akbarian is interested in Prefrontal cortex, which is a field of Neuroscience. His Computational biology study also includes

  • Epigenome that intertwine with fields like Epigenomics, Repressor, Regulation of gene expression, Haploinsufficiency and Gene knockdown,
  • Genome which is related to area like Genetic association,
  • Psychiatric genetics that connect with fields like CRISPR, Induced pluripotent stem cell, Treatment response and Polygenic risk score.

His studies deal with areas such as Schizophrenia, Histone and Human brain as well as Epigenetics. His study on Histone is covered under Genetics. His Chromatin study incorporates themes from Enhancer, Transcriptome and Neocortex.

Between 2018 and 2021, his most popular works were:

  • A computational tool (H-MAGMA) for improved prediction of brain-disorder risk genes by incorporating brain chromatin interaction profiles (56 citations)
  • CommonMind Consortium provides transcriptomic and epigenomic data for Schizophrenia and Bipolar Disorder. (36 citations)
  • Prefrontal parvalbumin interneurons require juvenile social experience to establish adult social behavior. (23 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • DNA
  • Genetics

His main research concerns Neuroscience, Chromatin, Gene, Epigenetics and Prefrontal cortex. His Neuroscience research is multidisciplinary, incorporating elements of Haploinsufficiency and Gene knockdown. Schahram Akbarian has included themes like Regulation of gene expression, Genome, Repressor and Epigenome in his Chromatin study.

His Gene research is multidisciplinary, incorporating perspectives in Dopaminergic, Psychosis, Cell type and Human brain. Epigenetics is a subfield of Genetics that he explores. His study in Prefrontal cortex is interdisciplinary in nature, drawing from both Juvenile, Autism, Optogenetics, Social isolation and Metabolome.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Deficiency of methyl-CpG binding protein-2 in CNS neurons results in a Rett-like phenotype in mice

Richard Z. Chen;Schahram Akbarian;Schahram Akbarian;Matthew Tudor;Rudolf Jaenisch.
Nature Genetics (2001)

1302 Citations

Gene expression for glutamic acid decarboxylase is reduced without loss of neurons in prefrontal cortex of schizophrenics.

Schahram Akbarian;James J. Kim;Steven G. Potkin;Jennifer O. Hagman.
Archives of General Psychiatry (1995)

1129 Citations

Altered Distribution of Nicotinamide-Adenine Dinucleotide Phosphate—Diaphorase Cells in Frontal Lobe of Schizophrenics Implies Disturbances of Cortical Development

Schahram Akbarian;William E. Bunney;Steven G. Potkin;Sharon B. Wigal.
Archives of General Psychiatry (1993)

865 Citations

Distorted distribution of nicotinamide-adenine dinucleotide phosphate-diaphorase neurons in temporal lobe of schizophrenics implies anomalous cortical development.

Schahram Akbarian;Angel Viñuela;James J. Kim;Steven G. Potkin.
Archives of General Psychiatry (1993)

591 Citations

Selective alterations in gene expression for NMDA receptor subunits in prefrontal cortex of schizophrenics

S Akbarian;NJ Sucher;D Bradley;A Tafazzoli.
The Journal of Neuroscience (1996)

538 Citations

Developmental and regional expression pattern of a novel NMDA receptor- like subunit (NMDAR-L) in the rodent brain

NJ Sucher;S Akbarian;CL Chi;CL Leclerc.
The Journal of Neuroscience (1995)

509 Citations

Maldistribution of Interstitial Neurons in Prefrontal White Matter of the Brains of Schizophrenic Patients

Schahram Akbarian;James J. Kim;Steven G. Pothin;William P. Hetrick.
Archives of General Psychiatry (1996)

483 Citations

Antidepressant-like effects of the histone deacetylase inhibitor, sodium butyrate, in the mouse

Frederick Albert Schroeder;Cong L. Lin;Wim E. Crusio;Schahram Akbarian.
Biological Psychiatry (2007)

478 Citations

DNA Methylation in the Human Cerebral Cortex Is Dynamically Regulated throughout the Life Span and Involves Differentiated Neurons

Kimberly D. Siegmund;Caroline M. Connor;Mihaela Campan;Tiffany I. Long.
PLOS ONE (2007)

458 Citations

Epigenetic mechanisms in neurological disease

Mira Jakovcevski;Schahram Akbarian.
Nature Medicine (2012)

396 Citations

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