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Medicine

D-Index
124
Citations
57636
World Ranking
3222
National Ranking
1775

Research.com Recognitions

  • 2011 - Rhoda and Bernard Sarnat International Prize in Mental Health, National Academy of Medicine
  • 1986 - Member of the National Academy of Medicine (NAM)
  • 1951 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

William E. Bunney is affiliated with the University of California, Irvine in the United States. Their research encompasses multiple areas within biochemistry, genetics, molecular biology, and neuroscience. The primary focus lies in molecular biology, cellular and molecular neuroscience, genetics, biological psychiatry, and psychiatry and mental health.

The scientist has contributed extensively to topics including tryptophan and brain disorders, neuroscience and neuropharmacology research, RNA research and splicing, bipolar disorder and treatment, stress responses and cortisol, genomics and chromatin dynamics, and single-cell and spatial transcriptomics.

Some of the recent publications include:

  • Rare coding variants in ten genes confer substantial risk for schizophrenia, 2022, Nature
  • Single nucleus multiomics identifies ZEB1 and MAFB as candidate regulators of Alzheimer's disease-specific cis-regulatory elements, 2023, Cell Genomics
  • Rapid-acting antidepressants and the circadian clock, 2021, Neuropsychopharmacology
  • Mitochondria DNA copy number, mitochondria DNA total somatic deletions, Complex I activity, synapse number, and synaptic mitochondria number are altered in schizophrenia and bipolar disorder, 2022, Translational Psychiatry
  • Identification of potential blood biomarkers associated with suicide in major depressive disorder, 2022, Translational Psychiatry

Frequent co-authors with whom they have collaborated include:

  • Stanley J. Watson
  • Huda Akil
  • R Myers
  • Blynn G. Bunney
  • Marquis P. Vawter

Publication venues where they have frequently published are:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Translational Psychiatry
  • Biological Psychiatry
  • Nature
  • Cell Genomics

Awards received throughout their career include:

  • Rhoda and Bernard Sarnat International Prize in Mental Health, National Academy of Medicine, 2011
  • Member of the National Academy of Medicine (NAM), 1986
  • Fellow of the American Association for the Advancement of Science (AAAS), 1951

Best Publications

  • Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs

    S. Hong Lee;Stephan Ripke;Stephan Ripke;Benjamin M. Neale;Benjamin M. Neale;Stephen V. Faraone

  • Norepinephrine in Depressive Reactions: A Review

    William E. Bunney;John M. Davis

  • Genome-wide association study identifies 30 loci associated with bipolar disorder

    Eli A. Stahl;Eli A. Stahl;Gerome Breen;Andreas J. Forstner;Andrew McQuillin

  • Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4

    Pamela Sklar;Pamela Sklar;Stephan Ripke;Stephan Ripke;Laura J. Scott;Ole A. Andreassen

  • Genomic Relationships, Novel Loci, and Pleiotropic Mechanisms across Eight Psychiatric Disorders

    Phil H. Lee;Verneri Anttila;Hyejung Won;Yen-Chen A. Feng

  • Aggression, suicide, and serotonin: relationships to CSF amine metabolites.

    Gerald L Brown;Michael H. Ebert;Peter F. Goyer;David C. Jimerson

  • A Family Study of Schizoaffective, Bipolar I, Bipolar II, Unipolar, and Normal Control Probands

    Elliot S. Gershon;Joel Hamovit;Juliet J. Guroff;Eleanor Dibble

  • Gene expression for glutamic acid decarboxylase is reduced without loss of neurons in prefrontal cortex of schizophrenics.

    Schahram Akbarian;James J. Kim;Steven G. Potkin;Jennifer O. Hagman

  • Altered Distribution of Nicotinamide-Adenine Dinucleotide Phosphate—Diaphorase Cells in Frontal Lobe of Schizophrenics Implies Disturbances of Cortical Development

    Schahram Akbarian;William E. Bunney;Steven G. Potkin;Sharon B. Wigal

  • The biological basis of an antidepressant response to sleep deprivation and relapse: review and hypothesis.

    Joseph C. Wu;William E. Bunney

  • Genomic Dissection of Bipolar Disorder and Schizophrenia, Including 28 Subphenotypes

    Douglas M. Ruderfer;Stephan Ripke;Stephan Ripke;Stephan Ripke;Andrew McQuillin;James Boocock

  • Altered cortical glutamatergic and GABAergic signal transmission with glial involvement in depression

    Prabhakara V Choudary;M. Molnar;S. J. Evans;H. Tomita

  • Psychiatric genome-wide association study analyses implicate neuronal, immune and histone pathways

    Colm O'Dushlaine;Lizzy Rossin;Phil H. Lee;Laramie Duncan;Laramie Duncan

  • Cerebral glucography with positron tomography. Use in normal subjects and in patients with schizophrenia.

    Monte S. Buchsbaum;David H. Ingvar;Robert Kessler;Robert N. Waters

  • Animal model of depression. I. Review of evidence: implications for research.

    William T. McKinney;William E. Bunney

  • Methods for Reliable Longitudinal Observation of Behavior: Development of a Method for Systematic Observation of Emotional Behavior on Psychiatric Wards

    William E. Bunney;David A. Hamburg

  • Circadian patterns of gene expression in the human brain and disruption in major depressive disorder

    Jun Z. Li;Blynn G. Bunney;Fan Meng;Megan H. Hagenauer

  • Distorted distribution of nicotinamide-adenine dinucleotide phosphate-diaphorase neurons in temporal lobe of schizophrenics implies anomalous cortical development.

    Schahram Akbarian;Angel Viñuela;James J. Kim;Steven G. Potkin

  • Selective alterations in gene expression for NMDA receptor subunits in prefrontal cortex of schizophrenics

    S Akbarian;NJ Sucher;D Bradley;A Tafazzoli

  • Genome wide meta-analysis identifies genomic relationships, novel loci, and pleiotropic mechanisms across eight psychiatric disorders

    Lee Ph;Anttila;Won H

Frequent Co-Authors

Huda Akil
Huda Akil University of Michigan–Ann Arbor
Edward G. Jones
Edward G. Jones University of California, Davis
Richard M. Myers
Richard M. Myers HudsonAlpha Institute for Biotechnology
Alan F. Schatzberg
Alan F. Schatzberg Stanford University
Steven G. Potkin
Steven G. Potkin University of California, Irvine
Stanley J. Watson
Stanley J. Watson University of Michigan–Ann Arbor
Jack D. Barchas
Jack D. Barchas Cornell University
Monte S. Buchsbaum
Monte S. Buchsbaum University of California, San Diego
Jun Li
Jun Li University of Oklahoma Health Sciences Center
Joseph C. Wu
Joseph C. Wu Stanford University

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