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Ashley M. Buckle

Ashley M. Buckle

D-Index & Metrics

Biology and Biochemistry

D-Index
54
Citations
10286
World Ranking
15650
National Ranking
431

Overview

Ashley M. Buckle is a researcher affiliated with Monash University in Australia, whose work spans key areas within biochemistry, genetics, molecular biology, and medicine. Their research portfolio encompasses a range of subfields, including molecular biology, immunology, radiology, nuclear medicine and imaging, genetics, and cancer research.

The scientist has contributed to multiple topics in life sciences, notably in monoclonal and polyclonal antibodies research, protease and inhibitor mechanisms, cell adhesion molecules research, coagulation and bradykinin pathways, receptor mechanisms and signaling, COVID-19 clinical research studies, and SARS-CoV-2 and COVID-19 research.

Recent notable papers authored or co-authored by Ashley M. Buckle include:

  • A Comprehensive Phylogenetic Analysis of the Serpin Superfamily, 2021, Molecular Biology and Evolution
  • Development and Differentiation in Monobodies Based on the Fibronectin Type 3 Domain, 2020, Cells
  • Conformational diversity facilitates antibody mutation trajectories and discrimination between foreign and self-antigens, 2020, Proceedings of the National Academy of Sciences
  • Alpha-1-antitrypsin antagonizes COVID-19: a review of the epidemiology, molecular mechanisms, and clinical evidence, 2023, Biochemical Society Transactions
  • Structural Studies of Thyroid Peroxidase Show the Monomer Interacting With Autoantibodies in Thyroid Autoimmune Disease, 2020, Endocrinology

Their frequent co-authors include Peter G. Chandler, Xiyuan Bai, Edward D. Chan, Robert A. Sandhaus, and Benjamin T. Porebski, indicating a collaborative research environment engaging experts in related fields.

Ashley M. Buckle's research has been published extensively in venues such as bioRxiv (Cold Spring Harbor Laboratory), the International Journal of Molecular Sciences, Scientific Reports, the Journal of Biological Chemistry, and the Journal of Visualized Experiments. This distribution reflects participation in both preprint and peer-reviewed research dissemination channels.

Best Publications

  • An overview of the serpin superfamily

    Ruby H P Law;Qingwei Zhang;Sheena McGowan;Ashley Maurice Buckle

  • PROTEIN-PROTEIN RECOGNITION : CRYSTAL STRUCTURAL ANALYSIS OF A BARNASE-BARSTAR COMPLEX AT 2.0-A RESOLUTION

    Ashley M. Buckle;Gideon Schreiber;Alan R. Fersht

  • The role of protein dynamics in the evolution of new enzyme function

    Eleanor Campbell;Miriam Kaltenbach;Galen J Correy;Paul D Carr

  • A Common Fold Mediates Vertebrate Defense and Bacterial Attack

    Carlos J. Rosado;Ashley M. Buckle;Ruby H. P. Law;Rebecca E. Butcher;Rebecca E. Butcher

  • The MACPF/CDC family of pore-forming toxins.

    Carlos Joaquim Rosado;Stephanie Kondos;Tara Elaina Bull;Michael Kuiper

  • T cell receptor recognition of a 'super-bulged' major histocompatibility complex class I-bound peptide.

    Fleur Elizabeth Tynan;Scott R Burrows;Ashley Maurice Buckle;Craig Steven Clements

  • GABA production by glutamic acid decarboxylase is regulated by a dynamic catalytic loop

    G Fenalti;R.H.P Law;A.M Buckle;C Langendorf

  • A structural model for GroEL-polypeptide recognition.

    Ashley M. Buckle;Ralph Zahn;Alan R. Fersht

  • Stability and function: two constraints in the evolution of barstar and other proteins

    Gideon Schreiber;Ashley M Buckle;Alan R Fersht

  • Consensus protein design

    Benjamin T. Porebski;Ashley M. Buckle

  • Chaperone activity and structure of monomeric polypeptide binding domains of GroEL.

    Ralph Zahn;Ashley M. Buckle;Sarah Perrett;Christopher M. Johnson

  • Structural and energetic responses to cavity-creating mutations in hydrophobic cores: observation of a buried water molecule and the hydrophilic nature of such hydrophobic cavities.

    Ashley M. Buckle;Patrick Cramer;Alan R. Fersht

  • Refolding chromatography with immobilized mini-chaperones

    Myriam M. Altamirano;Ralph Golbik;Ralph Zahn;Ashley M. Buckle

  • Structural basis for the inhibition of the essential Plasmodium falciparum M1 neutral aminopeptidase

    Sheena McGowan;Corrine Joy Porter;Jonathan Lowther;Colin M Stack;Colin M Stack

  • Control of the coagulation system by serpins: getting by with a little help from glycosaminoglycans

    Robert Neil Pike;Ashley Maurice Buckle;Bernard Le Bonniec;Frank C Church

  • The Crystal Structure of Af1521 a Protein from Archaeoglobus Fulgidus with Homology to the Non-Histone Domain of Macroh2A

    Mark D Allen;Ashley Maurice Buckle;Suzanne C Cordell;Jan Lowe

  • Identification of the primary collagen-binding surface on human glycoprotein VI by site-directed mutagenesis and by a blocking phage antibody.

    Peter A. Smethurst;Lotta Joutsi-Korhonen;Marie N. O'Connor;Erica Wilson

  • Crystal structural analysis of mutations in the hydrophobic cores of barnase

    Ashley M. Buckle;Kirn Henrick;Alan R. Fersht

  • Substrate-guided design of a potent and selective kallikrein-related peptidase inhibitor for kallikrein 4

    Joakim E Swedberg;Laura V Nigon;Janet C Reid;Simon J de Veer

  • Scabies Mite Inactivated Serine Protease Paralogs Inhibit the Human Complement System

    Frida C Bergstrom;Simone Reynolds;Masego Johnstone;Robert Neil Pike

Frequent Co-Authors

James C. Whisstock
James C. Whisstock Monash University
Stephen P. Bottomley
Stephen P. Bottomley Monash University
Alan R. Fersht
Alan R. Fersht University of Cambridge
Robert N. Pike
Robert N. Pike La Trobe University
Jamie Rossjohn
Jamie Rossjohn Monash University
Colin J. Jackson
Colin J. Jackson Australian National University
Jiangning Song
Jiangning Song Monash University
Graham J. Lieschke
Graham J. Lieschke Monash University
Geoffrey I. Webb
Geoffrey I. Webb Monash University
Peter R. Schofield
Peter R. Schofield Neuroscience Research Australia

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