Graham J. Lieschke spends much of his time researching Immunology, Zebrafish, Granulocyte macrophage colony-stimulating factor, Haematopoiesis and Granulocyte colony-stimulating factor. His Immunology research integrates issues from Genetically modified mouse and Lymph. His Zebrafish research incorporates themes from Molecular biology, Computational biology, Disease and Transcription factor.
His work carried out in the field of Granulocyte macrophage colony-stimulating factor brings together such families of science as Cancer research, Recombinant DNA, Colony-stimulating factor, Lung and Macrophage. His Haematopoiesis research is multidisciplinary, relying on both Cancer and Granulocyte macrophage colony-stimulating factor receptor. He interconnects Pulmonary pathology, Surfactant homeostasis, Pulmonary alveolar proteinosis, Alveolar proteinosis and Progenitor cell in the investigation of issues within Granulocyte macrophage colony-stimulating factor receptor.
Graham J. Lieschke mostly deals with Zebrafish, Cell biology, Immunology, Molecular biology and Genetics. His work deals with themes such as Transgene, Cellular differentiation, Myeloid, Regulation of gene expression and Computational biology, which intersect with Zebrafish. The Myelopoiesis research Graham J. Lieschke does as part of his general Cell biology study is frequently linked to other disciplines of science, such as Population, therefore creating a link between diverse domains of science.
His Immunology research is multidisciplinary, incorporating elements of Haematopoiesis and Granulocyte colony-stimulating factor. He combines subjects such as Progenitor cell and Granulocyte macrophage colony-stimulating factor receptor with his study of Haematopoiesis. His Molecular biology study incorporates themes from Signal transduction, Growth factor, Gene knockdown and Fusion protein.
His scientific interests lie mostly in Cell biology, Microbiology, Zebrafish, In vivo and Innate immune system. His Cell biology research includes themes of Regulation of gene expression and Genetic screen. The Regulation of gene expression study combines topics in areas such as Immunology and Alternative splicing.
The study incorporates disciplines such as Thrombopoietin and Neofunctionalization in addition to Zebrafish. As part of the same scientific family, he usually focuses on Innate immune system, concentrating on Macrophage and intersecting with Beta oxidation, Inflammation, Arthritis, THP1 cell line and Proinflammatory cytokine. His work on Stem cell factor is typically connected to Subfunctionalization as part of general Haematopoiesis study, connecting several disciplines of science.
His main research concerns Innate immune system, Microbiology, Macrophage, Leukocyte migration and Immunity. Innate immune system is the subject of his research, which falls under Immunology. When carried out as part of a general Microbiology research project, his work on Antibiotic resistance is frequently linked to work in Membrane protein, Cardiolipin, Staphylococcal infections and Daptomycin, therefore connecting diverse disciplines of study.
His research integrates issues of Arthritis, Inflammation, Proinflammatory cytokine, Beta oxidation and Mitochondrial ROS in his study of Macrophage. Graham J. Lieschke has included themes like Acquired immune system, Pathogen and Phagocytosis in his Leukocyte migration study.
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Animal models of human disease: zebrafish swim into view.
Graham J Lieschke;Peter David Currie.
Nature Reviews Genetics (2007)
Granulocyte Colony-Stimulating Factor and Granulocyte-Macrophage Colony-Stimulating Factor
Graham J. Lieschke;Antony W. Burgess.
The New England Journal of Medicine (1992)
Mice lacking granulocyte colony-stimulating factor have chronic neutropenia, granulocyte and macrophage progenitor cell deficiency, and impaired neutrophil mobilization
Graham J. Lieschke;Dianne Grail;George Hodgson;Donald Metcalf.
Granulocyte/macrophage colony-stimulating factor-deficient mice show no major perturbation of hematopoiesis but develop a characteristic pulmonary pathology
Edouard Stanley;Graham J. Lieschke;Graham J. Lieschke;Dianne Grail;Donald Metcalf.
Proceedings of the National Academy of Sciences of the United States of America (1994)
mpeg1 promoter transgenes direct macrophage-lineage expression in zebrafish
Felix Ellett;Felix Ellett;Luke Pase;John W. Hayman;Alex Andrianopoulos.
Morphologic and functional characterization of granulocytes and macrophages in embryonic and adult zebrafish
Graham J. Lieschke;Andrew C. Oates;Andrew C. Oates;Meredith O. Crowhurst;Meredith O. Crowhurst;Alister C. Ward;Alister C. Ward.
Granulocyte colony-stimulating factor and granulocyte-macrophage colony-stimulating factor (2).
G J Lieschke;A W Burgess.
The New England Journal of Medicine (1992)
The influence of granulocyte/macrophage colony‐stimulating factor on dendritic cell levels in mouse lymphoid organs
David Vremec;Graham J. Lieschke;Ashley R. Dunn;Lorraine Robb.
European Journal of Immunology (1997)
Filgrastim in Patients with Chemotherapy-Induced Febrile Neutropenia: A Double-Blind, Placebo-Controlled Trial
Darryl W. Maher;Graham J. Lieschke;Michael Green;James Bishop.
Annals of Internal Medicine (1994)
DNAzyme targeting c-jun suppresses skin cancer growth
Hong Cai;Fernando S. Santiago;Leonel Prado-Lourenco;Bo Wang;Bo Wang.
Science Translational Medicine (2012)
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