D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 61 Citations 15,783 151 World Ranking 7329 National Ranking 199

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Cancer
  • DNA

Graham J. Lieschke spends much of his time researching Immunology, Zebrafish, Granulocyte macrophage colony-stimulating factor, Haematopoiesis and Granulocyte colony-stimulating factor. His Immunology research integrates issues from Genetically modified mouse and Lymph. His Zebrafish research incorporates themes from Molecular biology, Computational biology, Disease and Transcription factor.

His work carried out in the field of Granulocyte macrophage colony-stimulating factor brings together such families of science as Cancer research, Recombinant DNA, Colony-stimulating factor, Lung and Macrophage. His Haematopoiesis research is multidisciplinary, relying on both Cancer and Granulocyte macrophage colony-stimulating factor receptor. He interconnects Pulmonary pathology, Surfactant homeostasis, Pulmonary alveolar proteinosis, Alveolar proteinosis and Progenitor cell in the investigation of issues within Granulocyte macrophage colony-stimulating factor receptor.

His most cited work include:

  • Animal models of human disease: zebrafish swim into view. (1478 citations)
  • Mice lacking granulocyte colony-stimulating factor have chronic neutropenia, granulocyte and macrophage progenitor cell deficiency, and impaired neutrophil mobilization (767 citations)
  • Granulocyte Colony-Stimulating Factor and Granulocyte-Macrophage Colony-Stimulating Factor (757 citations)

What are the main themes of his work throughout his whole career to date?

Graham J. Lieschke mostly deals with Zebrafish, Cell biology, Immunology, Molecular biology and Genetics. His work deals with themes such as Transgene, Cellular differentiation, Myeloid, Regulation of gene expression and Computational biology, which intersect with Zebrafish. The Myelopoiesis research Graham J. Lieschke does as part of his general Cell biology study is frequently linked to other disciplines of science, such as Population, therefore creating a link between diverse domains of science.

His Immunology research is multidisciplinary, incorporating elements of Haematopoiesis and Granulocyte colony-stimulating factor. He combines subjects such as Progenitor cell and Granulocyte macrophage colony-stimulating factor receptor with his study of Haematopoiesis. His Molecular biology study incorporates themes from Signal transduction, Growth factor, Gene knockdown and Fusion protein.

He most often published in these fields:

  • Zebrafish (76.09%)
  • Cell biology (44.02%)
  • Immunology (30.43%)

What were the highlights of his more recent work (between 2016-2021)?

  • Cell biology (44.02%)
  • Microbiology (10.33%)
  • Zebrafish (76.09%)

In recent papers he was focusing on the following fields of study:

His scientific interests lie mostly in Cell biology, Microbiology, Zebrafish, In vivo and Innate immune system. His Cell biology research includes themes of Regulation of gene expression and Genetic screen. The Regulation of gene expression study combines topics in areas such as Immunology and Alternative splicing.

The study incorporates disciplines such as Thrombopoietin and Neofunctionalization in addition to Zebrafish. As part of the same scientific family, he usually focuses on Innate immune system, concentrating on Macrophage and intersecting with Beta oxidation, Inflammation, Arthritis, THP1 cell line and Proinflammatory cytokine. His work on Stem cell factor is typically connected to Subfunctionalization as part of general Haematopoiesis study, connecting several disciplines of science.

Between 2016 and 2021, his most popular works were:

  • Chromatin-remodeling factor SMARCD2 regulates transcriptional networks controlling differentiation of neutrophil granulocytes (47 citations)
  • Intron retention enhances gene regulatory complexity in vertebrates (35 citations)
  • The Neutrophil Nucleus: An Important Influence on Neutrophil Migration and Function. (30 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Cancer
  • DNA

His main research concerns Innate immune system, Microbiology, Macrophage, Leukocyte migration and Immunity. Innate immune system is the subject of his research, which falls under Immunology. When carried out as part of a general Microbiology research project, his work on Antibiotic resistance is frequently linked to work in Membrane protein, Cardiolipin, Staphylococcal infections and Daptomycin, therefore connecting diverse disciplines of study.

His research integrates issues of Arthritis, Inflammation, Proinflammatory cytokine, Beta oxidation and Mitochondrial ROS in his study of Macrophage. Graham J. Lieschke has included themes like Acquired immune system, Pathogen and Phagocytosis in his Leukocyte migration study.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Animal models of human disease: zebrafish swim into view.

Graham J Lieschke;Peter David Currie.
Nature Reviews Genetics (2007)

2318 Citations

Granulocyte Colony-Stimulating Factor and Granulocyte-Macrophage Colony-Stimulating Factor

Graham J. Lieschke;Antony W. Burgess.
The New England Journal of Medicine (1992)

1223 Citations

Mice lacking granulocyte colony-stimulating factor have chronic neutropenia, granulocyte and macrophage progenitor cell deficiency, and impaired neutrophil mobilization

Graham J. Lieschke;Dianne Grail;George Hodgson;Donald Metcalf.
Blood (1994)

1123 Citations

Granulocyte/macrophage colony-stimulating factor-deficient mice show no major perturbation of hematopoiesis but develop a characteristic pulmonary pathology

Edouard Stanley;Graham J. Lieschke;Graham J. Lieschke;Dianne Grail;Donald Metcalf.
Proceedings of the National Academy of Sciences of the United States of America (1994)

1030 Citations

mpeg1 promoter transgenes direct macrophage-lineage expression in zebrafish

Felix Ellett;Felix Ellett;Luke Pase;John W. Hayman;Alex Andrianopoulos.
Blood (2011)

683 Citations

Morphologic and functional characterization of granulocytes and macrophages in embryonic and adult zebrafish

Graham J. Lieschke;Andrew C. Oates;Andrew C. Oates;Meredith O. Crowhurst;Meredith O. Crowhurst;Alister C. Ward;Alister C. Ward.
Blood (2001)

525 Citations

Granulocyte colony-stimulating factor and granulocyte-macrophage colony-stimulating factor (2).

G J Lieschke;A W Burgess.
The New England Journal of Medicine (1992)

475 Citations

The influence of granulocyte/macrophage colony‐stimulating factor on dendritic cell levels in mouse lymphoid organs

David Vremec;Graham J. Lieschke;Ashley R. Dunn;Lorraine Robb.
European Journal of Immunology (1997)

333 Citations

Filgrastim in Patients with Chemotherapy-Induced Febrile Neutropenia: A Double-Blind, Placebo-Controlled Trial

Darryl W. Maher;Graham J. Lieschke;Michael Green;James Bishop.
Annals of Internal Medicine (1994)

308 Citations

DNAzyme targeting c-jun suppresses skin cancer growth

Hong Cai;Fernando S. Santiago;Leonel Prado-Lourenco;Bo Wang;Bo Wang.
Science Translational Medicine (2012)

262 Citations

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