D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 66 Citations 18,026 180 World Ranking 3830 National Ranking 1936

Research.com Recognitions

Awards & Achievements

2015 - Member of the National Academy of Medicine (NAM)

Member of the Association of American Physicians

Overview

What is she best known for?

The fields of study she is best known for:

  • Immune system
  • Cancer
  • Cytokine

Anna Huttenlocher spends much of her time researching Cell biology, Calpain, Cell migration, Focal adhesion and Integrin. Her Cell biology research integrates issues from Cell adhesion and Cytoskeleton. Her work carried out in the field of Calpain brings together such families of science as Spectrin, Proteolysis and Tyrosine phosphorylation.

Her work deals with themes such as Inflammation, CDC42, Signal transduction, Actin cytoskeleton and Extracellular matrix, which intersect with Cell migration. Her Focal adhesion research incorporates elements of Molecular biology and PTK2. Her study in Integrin is interdisciplinary in nature, drawing from both Fibronectin and Cell polarity.

Her most cited work include:

  • Integrins in Cell Migration (540 citations)
  • Immune dysregulation in human subjects with heterozygous germline mutations in CTLA4 (485 citations)
  • Adhesion in cell migration. (467 citations)

What are the main themes of her work throughout her whole career to date?

Cell biology, Zebrafish, Immunology, Inflammation and Chemotaxis are her primary areas of study. Her Cell biology research includes themes of Integrin, Cell migration and Cell adhesion. Her Cell migration study combines topics from a wide range of disciplines, such as Calpain and Actin.

Her studies in Zebrafish integrate themes in fields like Cancer research, Live cell imaging, Wound healing, Innate immune system and In vivo. Her Chemotaxis study incorporates themes from Cell signaling, Signal transduction, Cyclin-dependent kinase 2 and Cell polarity. In her work, Actin cytoskeleton is strongly intertwined with Extracellular matrix, which is a subfield of Focal adhesion.

She most often published in these fields:

  • Cell biology (61.67%)
  • Zebrafish (27.31%)
  • Immunology (18.06%)

What were the highlights of her more recent work (between 2018-2021)?

  • Cell biology (61.67%)
  • Zebrafish (27.31%)
  • Inflammation (16.74%)

In recent papers she was focusing on the following fields of study:

Anna Huttenlocher mostly deals with Cell biology, Zebrafish, Inflammation, Innate immune system and Chemotaxis. Her work often combines Cell biology and Chemistry studies. Her work focuses on many connections between Zebrafish and other disciplines, such as Cancer research, that overlap with her field of interest in DNAJB1, PRKACA, Breast cancer, Steatohepatitis and Fatty liver.

Her biological study spans a wide range of topics, including Liver cancer, Thermal injury, Notochord and Calcium signaling. Her Innate immune system study combines topics from a wide range of disciplines, such as Aspergillus nidulans, Chronic granulomatous disease and Microbiology. Anna Huttenlocher combines subjects such as Cell migration, Cellular differentiation, Cyclin-dependent kinase 2, microRNA and Myosin with her study of Chemotaxis.

Between 2018 and 2021, her most popular works were:

  • Neutrophil plasticity in the tumor microenvironment. (83 citations)
  • Metformin modulates innate immune-mediated inflammation and early progression of NAFLD-associated hepatocellular carcinoma in zebrafish (35 citations)
  • Efficient Front-Rear Coupling in Neutrophil Chemotaxis by Dynamic Myosin II Localization. (25 citations)

In her most recent research, the most cited papers focused on:

  • Immune system
  • Cancer
  • Cytokine

Anna Huttenlocher mainly investigates Cell biology, Inflammation, Chemotaxis, Microbiology and Zebrafish. Her Cell biology research is multidisciplinary, incorporating elements of Sprouting angiogenesis and Neurite. She has included themes like Endothelium, Steatohepatitis, Fatty liver and Immune system in her Inflammation study.

Her Chemotaxis study combines topics in areas such as microRNA, Retinoic acid, Cellular differentiation and Cyclin-dependent kinase 2. Her Microbiology research includes elements of Aspergillus nidulans and Virulence. Her work carried out in the field of Zebrafish brings together such families of science as Wound healing, Tissue homeostasis, Thermal injury, STAT3 and Mesenchymal stem cell.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Integrins in Cell Migration

Anna Huttenlocher;Alan Rick Horwitz.
Cold Spring Harbor Perspectives in Biology (2011)

778 Citations

Adhesion in cell migration.

Anna Huttenlocher;Rebecca R Sandborg;Alan F Horwitz.
Current Opinion in Cell Biology (1995)

634 Citations

Calpain-mediated proteolysis of talin regulates adhesion dynamics

Santos J. Franco;Mary A. Rodgers;Benjamin J. Perrin;Jaewon Han.
Nature Cell Biology (2004)

632 Citations

Regulating cell migration: calpains make the cut.

Santos J. Franco;Anna Huttenlocher.
Journal of Cell Science (2005)

564 Citations

Immune dysregulation in human subjects with heterozygous germline mutations in CTLA4

Hye Sun Kuehn;Weiming Ouyang;Bernice Lo;Elissa K. Deenick;Elissa K. Deenick.
Science (2014)

548 Citations

Resolution of inflammation by retrograde chemotaxis of neutrophils in transgenic zebrafish

Jonathan R. Mathias;Benjamin J. Perrin;Ting-Xi Liu;John Kanki.
Journal of Leukocyte Biology (2006)

501 Citations

Neutrophil migration in infection and wound repair: going forward in reverse.

Sofia de Oliveira;Emily E. Rosowski;Anna Huttenlocher.
Nature Reviews Immunology (2016)

472 Citations

Regulation of Cell Migration by the Calcium-dependent Protease Calpain

Anna Huttenlocher;Sean P. Palecek;Qin Lu;Wenli Zhang.
Journal of Biological Chemistry (1997)

462 Citations

Modulation of cell migration by integrin-mediated cytoskeletal linkages and ligand-binding affinity.

Anna Huttenlocher;Mark H. Ginsberg;Alan F. Horwitz.
Journal of Cell Biology (1996)

435 Citations

Lyn is a redox sensor that mediates leukocyte wound attraction in vivo

Sa Kan Yoo;Taylor W. Starnes;Qing Deng;Anna Huttenlocher.
Nature (2011)

372 Citations

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