Mark R. Philips

Overview

Best Publications

• Endomembrane trafficking of ras: the CAAX motif targets proteins to the ER and Golgi.

  Edwin Choy;Vi K. Chiu;Joseph Silletti;Marianna Feoktistov

  971
  Citations

• Differential Localization of Rho Gtpases in Live Cells Regulation by Hypervariable Regions and Rhogdi Binding

  David Michaelson;Joseph Silletti;Gretchen Murphy;Peter D'Eustachio

  878
  Citations

• Ras signalling on the endoplasmic reticulum and the Golgi.

  Vi K. Chiu;Trever Bivona;Angela Hach;J. Bernard Sajous

  789
  Citations

• Regulating the regulator: post-translational modification of RAS

  Ian M. Ahearn;Kevin Haigis;Dafna Bar-Sagi;Mark R. Philips

  630
  Citations

• Shp2 Regulates Src Family Kinase Activity and Ras/Erk Activation by Controlling Csk Recruitment

  Si Qing Zhang;Wentian Yang;Maria I. Kontaridis;Trever G. Bivona

  549
  Citations

• PKC regulates a farnesyl-electrostatic switch on K-Ras that promotes its association with Bcl-XL on mitochondria and induces apoptosis.

  Trever G. Bivona;Steven E. Quatela;Brian O. Bodemann;Ian M. Ahearn

  544
  Citations

• Phospholipase Cγ activates Ras on the Golgi apparatus by means of RasGRP1

  Trever G. Bivona;Ignacio Pérez de Castro;Ian M. Ahearn;Theresa M. Grana

  527
  Citations

• Compartmentalized Ras/MAPK signaling.

  Adam Mor;Mark R. Philips

  518
  Citations

• Neutrophil adherence to endothelium is enhanced via adenosine A1 receptors and inhibited via adenosine A2 receptors.

  B N Cronstein;R I Levin;M Philips;R Hirschhorn

  472
  Citations

• Thematic review series: Lipid Posttranslational Modifications CAAX modification and membrane targeting of Ras

  Latasha P. Wright;Mark R. Philips

  430
  Citations

• Mammalian prenylcysteine carboxyl methyltransferase is in the endoplasmic reticulum

  Qun Dai;Edwin Choy;Vi Chiu;Julia Romano

  419
  Citations

• Receptor Activation Alters Inner Surface Potential During Phagocytosis

  Tony Yeung;Mauricio Terebiznik;Liming Yu;John Silvius

  398
  Citations

• Targeting RAS Membrane Association: Back to the Future for Anti-RAS Drug Discovery?

  Adrienne D. Cox;Channing J. Der;Mark R. Philips

  373
  Citations

• Depalmitoylated Ras traffics to and from the Golgi complex via a nonvesicular pathway

  J. Shawn Goodwin;Kimberly R. Drake;Carl Rogers;Latasha Wright

  348
  Citations

• Roles of the Rac1 and Rac3 GTPases in human tumor cell invasion

  Amanda Y. Chan;Salvatore J. Coniglio;Ya Yu Chuang;David Michaelson

  314
  Citations

• Carboxyl methylation of Ras-related proteins during signal transduction in neutrophils

  Mark R. Philips;Michael H. Pillinger;Roland Staud;Craig Volker

  271
  Citations

• Membranes as messengers in T cell adhesion signaling

  Michael L Dustin;Trever G Bivona;Mark R Philips

  256
  Citations

• Single-walled carbon nanotubes deliver peptide antigen into dendritic cells and enhance IgG responses to tumor-associated antigens.

  Carlos H. Villa;Tao Dao;Ian Ahearn;Nicole Fehrenbacher

  238
  Citations

• Modes of action of aspirin-like drugs: Salicylates inhibit Erk activation and integrin-dependent neutrophil adhesion

  Michael H. Pillinger;Constance Capodici;Pamela Rosenthal;Neil Kheterpal

  231
  Citations

• Postprenylation CAAX processing is required for proper localization of Ras but not Rho GTPases.

  David Michaelson;Wasif Ali;Vi K. Chiu;Martin Bergo

  208
  Citations