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Biology and Biochemistry

D-Index
55
Citations
14395
World Ranking
14846
National Ranking
1174

Overview

Ian A. Prior is affiliated with the University of Liverpool in the United Kingdom. Their main field of study is Biochemistry, Genetics and Molecular Biology, with research spanning 47 publications in this area.

The scientist's work covers several subfields including Molecular Biology, Genetics, Biomedical Engineering, Oncology, and Epidemiology. Within these, they have contributed notably to topics such as Protein Kinase Regulation and GTPase Signaling, Genomics and Chromatin Dynamics, Melanoma and MAPK Pathways, Cancer-related Molecular Pathways, Image Processing Techniques and Applications, Cell death mechanisms and regulation, and RNA Research and Splicing.

Recent papers authored or co-authored by Ian A. Prior include:

  • The Frequency of Ras Mutations in Cancer, 2020, Cancer Research
  • Trypanosoma brucei colonizes the tsetse gut via an immature peritrophic matrix in the proventriculus, 2020, Nature Microbiology
  • Ras protein abundance correlates with Ras isoform mutation patterns in cancer, 2023, Oncogene
  • The importance of Ras in drug resistance in cancer, 2021, British Journal of Pharmacology
  • Rules of engagement for condensins and cohesins guide mitotic chromosome formation, 2025, Science

Ian A. Prior has published books with Springer Science+Business Media, including the title Ras Activity and Signaling in 2021.

Common publication venues for their research work include bioRxiv (Cold Spring Harbor Laboratory), Zenodo (CERN European Organization for Nuclear Research), Cancer Research, Nature Microbiology, and Oncogene.

The scientist frequently collaborates with other researchers, including Alison J. Beckett, Fiona E. Hood, Fernanda Cisneros-Soberanis, N Pucekova, and William C. Earnshaw, with collaboration counts ranging from 4 to 16 shared publications.

Best Publications

  • A comprehensive survey of Ras mutations in cancer

    Ian A. Prior;Paul D. Lewis;Carla Mattos

  • Direct visualization of ras proteins in spatially distinct cell surface microdomains

    Ian A. Prior;Cornelia Muncke;Robert G. Parton;John F. Hancock

  • Uptake and intracellular fate of surface-modified gold nanoparticles

    Paola Nativo;Ian A. Prior;Mathias Brust

  • The Frequency of Ras Mutations in Cancer.

    Ian A. Prior;Fiona E. Hood;James L. Hartley

  • GTP-dependent segregation of H-ras from lipid rafts is required for biological activity.

    Ian A. Prior;Angus Harding;Jun Yan;Judith Sluimer

  • H-ras but Not K-ras Traffics to the Plasma Membrane through the Exocytic Pathway

    Ann Apolloni;Ian A. Prior;Margaret Lindsay;Robert G. Parton

  • Compartmentalization of Ras proteins.

    Ian A. Prior;John F. Hancock

  • The Ubiquitin Isopeptidase UBPY Regulates Endosomal Ubiquitin Dynamics and Is Essential for Receptor Down-regulation

    Paula E. Row;Ian A. Prior;John McCullough;Michael J. Clague

  • Ras trafficking, localization and compartmentalized signalling

    Ian A. Prior;John F. Hancock

  • Plasma membrane microdomains: organization, function and trafficking.

    Alex J. Laude;Ian A. Prior

  • Individual palmitoyl residues serve distinct roles in H-ras trafficking, microlocalization, and signaling.

    Sandrine Roy;Sarah Plowman;Barak Rotblat;Ian A. Prior

  • Flotillin-1/reggie-2 traffics to surface raft domains via a novel golgi-independent pathway. Identification of a novel membrane targeting domain and a role for palmitoylation.

    Isabel C. Morrow;Shane Rea;Sally Martin;Ian A. Prior

  • A TACC3/ch-TOG/clathrin complex stabilises kinetochore fibres by inter-microtubule bridging.

    Daniel G Booth;Fiona E Hood;Ian A Prior;Stephen J Royle

  • Activation of trypsinogen in large endocytic vacuoles of pancreatic acinar cells

    Mark W. Sherwood;Ian A. Prior;Svetlana G. Voronina;Stephanie L. Barrow

  • Three separable domains regulate GTP-dependent association of H-ras with the plasma membrane.

    Barak Rotblat;Ian A. Prior;Cornelia Muncke;Robert G. Parton

  • Ras proteins: paradigms for compartmentalised and isoform specific signalling

    Jasminka Omerovic;Alex J. Laude;Ian A. Prior

  • Docosahexaenoic Acid Alters the Size and Distribution of Cell Surface Microdomains

    Robert S. Chapkin;Naisyin Wang;Yang-Yi Fan;Joanne R. Lupton

  • Ras acylation, compartmentalization and signaling nanoclusters (Review).

    Yoav I Henis;John F Hancock;Ian A Prior

  • Palmitoylation and localisation of RAS isoforms are modulated by the hypervariable linker domain

    Alex J. Laude;Ian A. Prior

  • Intracellular mapping with SERS-encoded gold nanostars

    Laura Rodríguez-Lorenzo;Laura Rodríguez-Lorenzo;Zeljka Krpetic;Silvia Barbosa;Ramón A. Alvarez-Puebla

Frequent Co-Authors

John F. Hancock
John F. Hancock The University of Texas Health Science Center at Houston
Michael J. Clague
Michael J. Clague University of Liverpool
Mathias Brust
Mathias Brust University of Liverpool
Robert G. Parton
Robert G. Parton University of Queensland
David G. Spiller
David G. Spiller University of Manchester
Yoav I. Henis
Yoav I. Henis Tel Aviv University
Alexei V. Tepikin
Alexei V. Tepikin University of Liverpool
Sylvie Urbé
Sylvie Urbé University of Liverpool
Robert S. Chapkin
Robert S. Chapkin Texas A&M University
Michael R. H. White
Michael R. H. White University of Manchester

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