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D-Index & Metrics

Biology and Biochemistry

D-Index
67
Citations
19032
World Ranking
8112
National Ranking
629

Overview

David G. Fernig is affiliated with the University of Liverpool in the United Kingdom. Their research spans across multiple intersecting fields including biochemistry, genetics and molecular biology, as well as medicine. Within these broad domains, their work has a significant focus on molecular biology, cell biology, infectious diseases, immunology, and epidemiology.

The scientist's research covers several main topics, reflecting a diverse interest in biochemical and biomedical challenges. These topics include:

  • Proteoglycans and glycosaminoglycans research
  • Bacterial biofilms and quorum sensing
  • SARS-CoV-2 and COVID-19 research
  • Antibiotic resistance in bacteria
  • Influenza virus research studies
  • Fibroblast growth factor research
  • Alzheimer's disease research and treatments

David G. Fernig has contributed extensively to academic literature, with noteworthy recent publications mainly involving the structural and functional interactions between viral proteins and biochemical molecules. Selected recent papers demonstrate a concentration on SARS-CoV-2 and related biochemical mechanisms:

  • Heparin Inhibits Cellular Invasion by SARS-CoV-2: Structural Dependence of the Interaction of the Spike S1 Receptor-Binding Domain with Heparin, 2020, Thrombosis and Haemostasis
  • The 2019 coronavirus (SARS-CoV-2) surface protein (Spike) S1 Receptor Binding Domain undergoes conformational change upon heparin binding, 2020, bioRxiv (Cold Spring Harbor Laboratory)
  • Heparin inhibits cellular invasion by SARS-CoV-2: structural dependence of the interaction of the surface protein (spike) S1 receptor binding domain with heparin, 2020, bioRxiv (Cold Spring Harbor Laboratory)
  • Functions of exogenous FGF signals in regulation of fibroblast to myofibroblast differentiation and extracellular matrix protein expression, 2022, Open Biology
  • SARS-CoV-2 Spike S1 Receptor Binding Domain undergoes Conformational Change upon Interaction with Low Molecular Weight Heparins, 2020, bioRxiv (Cold Spring Harbor Laboratory)

Publications often appear in venues such as:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Biochemical Journal
  • Essays in Biochemistry
  • Fishes
  • Thrombosis and Haemostasis

David G. Fernig has collaborated frequently with a group of recurring co-authors, reinforcing their research network in related biochemical and molecular biology fields. Prominent co-authors include:

  • Edwin A. Yates
  • Marcelo A. Lima
  • Yong Li
  • Mark A. Skidmore
  • Keri McLean

Best Publications

  • Determination of size and concentration of gold nanoparticles from UV-vis spectra

    Wolfgang Haiss;Nguyen T. K. Thanh;Jenny Aveyard;David G. Fernig

  • Rational and Combinatorial Design of Peptide Capping Ligands for Gold Nanoparticles

    Lévy R;Thanh Nt;Doty Rc;Hussain I

  • A rapid method to estimate the concentration of citrate capped silver nanoparticles from UV-visible light spectra

    David Paramelle;Anton Sadovoy;Sergey Gorelik;Paul Free

  • Identification of the basic fibroblast growth factor binding sequence in fibroblast heparan sulfate.

    J. E. Turnbull;D. G. Fernig;Youquiang Ke;M. C. Wilkinson

  • Extremely Stable Water-Soluble Ag Nanoparticles

    R. Christopher Doty;T. Robert Tshikhudo;and Mathias Brust;David G. Fernig

  • Interactions of heparin/heparan sulfate with proteins: appraisal of structural factors and experimental approaches.

    Andrew K Powell;Edwin A Yates;David G Fernig;Jeremy E Turnbull

  • Kinase-Catalyzed Modification of Gold Nanoparticles: A New Approach to Colorimetric Kinase Activity Screening

    Zhenxin Wang;Raphaël Levy;David G. Fernig;Mathias Brust

  • Endocan Is a Novel Chondroitin Sulfate/Dermatan Sulfate Proteoglycan That Promotes Hepatocyte Growth Factor/Scatter Factor Mitogenic Activity

    David Béchard;Thaibaut Gentina;Maryse Delehedde;Arnaud Scherpereel

  • Fibroblast growth factors and their receptors: an information network controlling tissue growth, morphogenesis and repair.

    David G Fernig;John T Gallagher

  • Heparin Inhibits Cellular Invasion by SARS-CoV-2: Structural Dependence of the Interaction of the Spike S1 Receptor-Binding Domain with Heparin.

    Courtney J. Mycroft-West;Dunhao Su;Isabel Pagani;Timothy R. Rudd

  • Reversible Inhibition of Proliferation of Epithelial Cell Lines by Agaricus bisporus (Edible Mushroom) Lectin

    Lugang Yu;David G. Fernig;John A. Smith;Jeremy D. Milton

  • A Systems Biology Approach for the Investigation of the Heparin/Heparan Sulfate Interactome

    Alessandro Ori;Mark C. Wilkinson;David G. Fernig

  • The heparanome and regulation of cell function: structures, functions and challenges.

    Alessandro Ori;Mark Charles Wilkinson;David Garth Fernig

  • Long-term tracking of cells using inorganic nanoparticles as contrast agents: are we there yet?

    Arthur Taylor;Katie M. Wilson;Patricia Murray;David G. Fernig

  • The 2019 coronavirus (SARS-CoV-2) surface protein (Spike) S1 Receptor Binding Domain undergoes conformational change upon heparin binding

    Courtney J Mycroft-West;Dunhao Su;Stefano Elli;Yong Li

  • Hepatocyte growth factor/scatter factor binds with high affinity to dermatan sulfate

    Malcolm Lyon;Jon A. Deakin;Hassan Rahmoune;David G. Fernig

  • Interactions of Multiple Heparin Binding Growth Factors with Neuropilin-1 and Potentiation of the Activity of Fibroblast Growth Factor-2

    David C. West;Chris G. Rees;Laurence Duchesne;Susannah J. Patey

  • Interaction of Heparan Sulfate from Mammary Cells with Acidic Fibroblast Growth Factor (FGF) and Basic FGF REGULATION OF THE ACTIVITY OF BASIC FGF BY HIGH AND LOW AFFINITY BINDING SITES IN HEPARAN SULFATE

    Hassan Rahmoune;Hai-Lan Chen;John T. Gallagher;Philip S. Rudland

  • Differential effects of heparin saccharides on the formation of specific fibroblast growth factor (FGF) and FGF receptor complexes

    Olga Ostrovsky;Bluma Berman;John Gallagher;Barbara Mulloy

  • Programmed cell death in bovine mammary tissue during lactation and involution.

    C. J. Wilde;C. V. P. Addey;P. Li;D. G. Fernig

Frequent Co-Authors

Philip S. Rudland
Philip S. Rudland University of Liverpool
John A. Smith
John A. Smith University of Alabama at Birmingham
Jeremy E. Turnbull
Jeremy E. Turnbull University of Liverpool
Roger Barraclough
Roger Barraclough University of Liverpool
Marco Guerrini
Marco Guerrini Istituto G. Ronzoni
Malcolm Lyon
Malcolm Lyon University of Manchester
John T. Gallagher
John T. Gallagher University of Manchester
Jonathan M. Rhodes
Jonathan M. Rhodes University of Liverpool
Richard J. Nichols
Richard J. Nichols University of Liverpool
Neil G. Berry
Neil G. Berry University of Liverpool

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