World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
109
Citations
56417
World Ranking
988
National Ranking
604

Research.com Recognitions

  • 2012 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Jeffrey D. Esko is affiliated with the University of California, San Diego in the United States. Their research spans significant areas in biochemistry, genetics, molecular biology, and medicine, focusing on the molecular and cellular mechanisms underlying health and disease.

Their recent publication record includes a focus on viral infections and cellular interactions, particularly relating to SARS-CoV-2. Some notable papers are:

  • SARS-CoV-2 Infection Depends on Cellular Heparan Sulfate and ACE2 (2020, Cell)
  • SARS-CoV-2 Infection Depends on Cellular Heparan Sulfate and ACE2 (2020, bioRxiv - Cold Spring Harbor Laboratory)
  • Clofazimine broadly inhibits coronaviruses including SARS-CoV-2 (2021, Nature)
  • Spike-heparan sulfate interactions in SARS-CoV-2 infection (2022, Current Opinion in Structural Biology)
  • Cancer-cell-secreted miR-122 suppresses O-GlcNAcylation to promote skeletal muscle proteolysis (2022, Nature Cell Biology)

The scientist's work engages multiple topics, including:

  • Proteoglycans and glycosaminoglycans research
  • Glycosylation and glycoproteins research
  • COVID-19 clinical research studies
  • SARS-CoV-2 and COVID-19 research
  • Fibroblast growth factor research
  • Cell adhesion molecules research
  • Lysosomal storage disorders research

Their main fields of study consist of:

  • Biochemistry, Genetics and Molecular Biology
  • Medicine

Within these broader fields, subfields include:

  • Molecular Biology
  • Cell Biology
  • Infectious Diseases
  • Epidemiology
  • Immunology

Frequent publication venues where this scientist has contributed extensively include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • The FASEB Journal
  • Nature Communications
  • Journal of Biological Chemistry
  • Glycobiology

Among collaborators frequently working with this scientist are:

  • Thomas Mandel Clausen
  • Alejandro Gómez Toledo
  • Philip L.S.M. Gordts
  • Daniel R. Sandoval
  • Nathan E. Lewis

Jeffrey D. Esko was recognized as a Fellow of the American Association for the Advancement of Science (AAAS) in 2012.

Best Publications

  • Essentials of Glycobiology [Internet]

    Ajit Varki;Richard D Cummings;Jeffrey D Esko;Pamela Stanley

  • Cell surface, heparin-like molecules are required for binding of basic fibroblast growth factor to its high affinity receptor.

    Avner Yayon;Michael Klagsbrun;Jeffrey D. Esko;Philip Leder

  • Essentials of Glycobiology

    Ajit Varki;Richard D Cummings;Jeffrey D Esko;Hudson H Freeze

  • Heparan sulphate proteoglycans fine-tune mammalian physiology

    Joseph R. Bishop;Manuela Schuksz;Jeffrey D. Esko

  • Order out of chaos: assembly of ligand binding sites in heparan sulfate.

    Jeffrey D. Esko;Scott B. Selleck

  • Heparan Sulfate Proteoglycans

    Stephane Sarrazin;William C. Lamanna;Jeffrey D. Esko

  • The sweet and sour of cancer: glycans as novel therapeutic targets.

    Mark M. Fuster;Jeffrey D. Esko

  • Dengue virus infectivity depends on envelope protein binding to target cell heparan sulfate

    Yaping Chen;Terry Maguire;Ronald E. Hileman;Jonathan R. Fromm

  • A novel role for 3-O-sulfated heparan sulfate in herpes simplex virus 1 entry

    Deepak Shukla;Jian Liu;Peter Blaiklock;Nicholas W. Shworak;Nicholas W. Shworak

  • SARS-CoV-2 Infection Depends on Cellular Heparan Sulfate and ACE2.

    Thomas Mandel Clausen;Thomas Mandel Clausen;Thomas Mandel Clausen;Daniel R. Sandoval;Charlotte B. Spliid;Charlotte B. Spliid;Charlotte B. Spliid;Jessica Pihl;Jessica Pihl;Jessica Pihl

  • Molecular diversity of heparan sulfate

    Jeffrey D. Esko;Ulf Lindahl

  • Symbol Nomenclature for Graphical Representations of Glycans.

    Ajit Varki;Richard D. Cummings;Markus Aebi;Nicole H. Packer

  • Cell surface receptors for herpes simplex virus are heparan sulfate proteoglycans.

    Mei-Tsu Shieh;D. Wudunn;R. I. Montgomery;J. D. Esko

  • Demystifying Heparan Sulfate–Protein Interactions

    Ding Xu;Jeffrey D Esko

  • Animal cell mutants defective in glycosaminoglycan biosynthesis

    Jeffrey D. Esko;Tod E. Stewart;William H. Taylor

  • Loss of HIF-1α in endothelial cells disrupts a hypoxia-driven VEGF autocrine loop necessary for tumorigenesis

    Nan Tang;Lianchun Wang;Jeffrey Esko;Frank J. Giordano

  • Proteoglycans and Sulfated Glycosaminoglycans

    Jeffrey D Esko;Koji Kimata;Ulf Lindahl

  • Microbial adherence to and invasion through proteoglycans.

    K S Rostand;J D Esko

  • Endothelial heparan sulfate deficiency impairs L-selectin- and chemokine-mediated neutrophil trafficking during inflammatory responses.

    Lianchun Wang;Mark Fuster;P Sriramarao;Jeffrey D Esko

  • Disruption of Gastrulation and Heparan Sulfate Biosynthesis in EXT1-Deficient Mice

    Xin Lin;Ge Wei;Zhengzheng Shi;Laurence Dryer

Frequent Co-Authors

Gerald W. Hart
Gerald W. Hart University of Georgia
Pamela Stanley
Pamela Stanley Albert Einstein College of Medicine
Carolyn R. Bertozzi
Carolyn R. Bertozzi Stanford University
Ajit Varki
Ajit Varki University of California, San Diego
Yitzhak Tor
Yitzhak Tor University of California, San Diego
Richard D. Cummings
Richard D. Cummings Harvard Medical School
Hudson H. Freeze
Hudson H. Freeze Discovery Institute
Nathan E. Lewis
Nathan E. Lewis University of California, San Diego
Victor Nizet
Victor Nizet University of California, San Diego
Robert J. Linhardt
Robert J. Linhardt Rensselaer Polytechnic Institute

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Best Scientists Citing Jeffrey D. Esko

Trending Scientists