His scientific interests lie mostly in Biochemistry, Chondroitin sulfate, Heparan sulfate, Chondroitin and Dermatan sulfate. His Biochemistry study incorporates themes from Molecular biology and Cell biology. Kazuyuki Sugahara interconnects Growth factor, Midkine, Pleiotrophin, Neurite and Disaccharide in the investigation of issues within Chondroitin sulfate.
Membrane protein is closely connected to Glycosyltransferase in his research, which is encompassed under the umbrella topic of Heparan sulfate. His Chondroitin research incorporates themes from Amino acid, Wnt signaling pathway, 3'-Phosphoadenosine-5'-phosphosulfate and Phosphotransferase. His Dermatan sulfate research incorporates elements of Fibroblast growth factor, Neurotrophic factors, Oligosaccharide and Versican.
Kazuyuki Sugahara mostly deals with Biochemistry, Chondroitin sulfate, Sulfation, Dermatan sulfate and Heparan sulfate. His Biochemistry study frequently draws connections to other fields, such as Stereochemistry. The Chondroitin sulfate study combines topics in areas such as Pleiotrophin, Tetrasaccharide, Molecular biology, Epitope and Oligosaccharide.
His Sulfation research includes elements of Uronic acid, Heparin cofactor II, Carbohydrate conformation and Galactose. Kazuyuki Sugahara has included themes like Ehlers–Danlos syndrome, Growth factor and Decorin in his Dermatan sulfate study. His Heparan sulfate study combines topics in areas such as Glycosyltransferase, Gene, Transferase and Cancer research.
His main research concerns Chondroitin sulfate, Biochemistry, Glycosaminoglycan, Dermatan sulfate and Proteoglycan. His studies in Chondroitin sulfate integrate themes in fields like Sulfation, Polysaccharide, Enzyme, Stereochemistry and Oligosaccharide. His research in Sulfation intersects with topics in Epitope and Pleiotrophin.
Biochemistry is closely attributed to Cell biology in his study. His Dermatan sulfate research is multidisciplinary, incorporating elements of Dysplasia and Short stature. His Proteoglycan research focuses on Molecular biology and how it connects with Hydrolase and Peptide sequence.
His primary scientific interests are in Biochemistry, Chondroitin sulfate, Proteoglycan, Cell biology and Dermatan sulfate. Kazuyuki Sugahara is interested in Chondroitin, which is a field of Biochemistry. His Chondroitin sulfate study integrates concerns from other disciplines, such as Heparan sulfate and Axon guidance.
His work carried out in the field of Proteoglycan brings together such families of science as Tetrasaccharide, Self-healing hydrogels and Glycosaminoglycan. The Extracellular matrix research he does as part of his general Cell biology study is frequently linked to other disciplines of science, such as Vascular endothelial growth factor binding, therefore creating a link between diverse domains of science. His work deals with themes such as Sulfation, Receptor, Plasma protein binding and Decorin, which intersect with Dermatan sulfate.
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Recent advances in the structural biology of chondroitin sulfate and dermatan sulfate
Kazuyuki Sugahara;Tadahisa Mikami;Toru Uyama;Souhei Mizuguchi.
Current Opinion in Structural Biology (2003)
Recent advances in the study of the biosynthesis and functions of sulfated glycosaminoglycans.
Kazuyuki Sugahara;Hiroshi Kitagawa.
Current Opinion in Structural Biology (2000)
Specific Molecular Interactions of Oversulfated Chondroitin Sulfate E with Various Heparin-binding Growth Factors IMPLICATIONS AS A PHYSIOLOGICAL BINDING PARTNER IN THE BRAIN AND OTHER TISSUES
Sarama Sathyaseelan Deepa;Yuko Umehara;Shigeki Higashiyama;Nobuyuki Itoh.
Journal of Biological Chemistry (2002)
Heparin and heparan sulfate biosynthesis.
Kazuyuki Sugahara;Hiroshi Kitagawa.
Iubmb Life (2002)
Composition of Perineuronal Net Extracellular Matrix in Rat Brain A DIFFERENT DISACCHARIDE COMPOSITION FOR THE NET-ASSOCIATED PROTEOGLYCANS
Sarama Sathyaseelan Deepa;Daneila Carulli;Clare Galtrey;Kate Rhodes.
Journal of Biological Chemistry (2006)
Chondroitin/dermatan sulfate in the central nervous system
Kazuyuki Sugahara;Tadahisa Mikami.
Current Opinion in Structural Biology (2007)
Microanalysis of glycosaminoglycan-derived oligosaccharides labeled with a fluorophore 2-aminobenzamide by high-performance liquid chromatography: application to disaccharide composition analysis and exosequencing of oligosaccharides.
Akiko Kinoshita;Kazuyuki Sugahara.
Analytical Biochemistry (1999)
The Tumor Suppressor EXT-like Gene EXTL2 Encodes an α1, 4-N-Acetylhexosaminyltransferase That TransfersN-Acetylgalactosamine and N-Acetylglucosamine to the Common Glycosaminoglycan-Protein Linkage Region THE KEY ENZYME FOR THE CHAIN INITIATION OF HEPARAN SULFATE
Hiroshi Kitagawa;Hiromi Shimakawa;Kazuyuki Sugahara.
Journal of Biological Chemistry (1999)
Oversulfated Chondroitin/Dermatan Sulfates Containing GlcAβ1/IdoAα1–3GalNAc(4,6-O-disulfate) Interact with L- and P-selectin and Chemokines
Hiroto Kawashima;Kazuyuki Atarashi;Mayumi Hirose;Jun Hirose.
Journal of Biological Chemistry (2002)
Potential therapeutic application of chondroitin sulfate/dermatan sulfate.
Shuhei Yamada;Kazuyuki Sugahara.
Current Drug Discovery Technologies (2008)
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