World's Best Scientists 2026 revealed!
Kazuyuki Sugahara

Kazuyuki Sugahara

Award Badge
Biology and Biochemistry
Japan
2023

D-Index & Metrics

Biology and Biochemistry

D-Index
92
Citations
24208
World Ranking
2256
National Ranking
138

Research.com Recognitions

  • 2023 - Research.com Biology and Biochemistry in Japan Leader Award

Overview

Kazuyuki Sugahara is affiliated with Hokkaido University in Japan. Their research primarily focuses on biochemistry, genetics, and molecular biology, with notable contributions across medicine and related subfields.

The scientist's work addresses various topics including:

  • Proteoglycans and glycosaminoglycans research
  • Glycosylation and glycoproteins research
  • Carbohydrate chemistry and synthesis
  • Connective tissue disorders research
  • Bone and dental protein studies
  • RNA modifications and cancer
  • Blood disorders and treatments

Within subfields, their publications span molecular biology, genetics, cell biology, organic chemistry, and rheumatology. The integration of these fields supports a multidisciplinary approach to understanding biochemical and medical phenomena.

Kazuyuki Sugahara has authored several papers, including:

  • "Pseudodiastrophic dysplasia expands the known phenotypic spectrum of defects in proteoglycan biosynthesis," 2020, Journal of Medical Genetics
  • "Investigation of action pattern of a novel chondroitin sulfate/dermatan sulfate 4-O-endosulfatase," 2020, Biochemical Journal
  • "Marine Bacteria as a Rich Source of Glycosaminoglycan-degrading Enzymes," 2020, Encyclopedia of Marine Biotechnology
  • "Pathogenic variants in uridine diphosphate nucleotidase (CANT1) or glucuronyltransferase (B3GAT3) causes a pseudodiastrophic dysplasia," 2021, The FASEB Journal

Their frequent coauthors include Alicia B. Byrne, Shuji Mizumoto, Shuhei Yamada, Hamish S. Scott, and Fuchuan Li. These collaborations reflect consistent partnerships across biochemical and genetic research areas.

Publication venues for their work encompass various journals and encyclopedias where topics intersect with molecular genetics and biochemistry:

  • Journal of Medical Genetics
  • Biochemical Journal
  • Encyclopedia of Marine Biotechnology
  • The FASEB Journal

Best Publications

  • Recent advances in the structural biology of chondroitin sulfate and dermatan sulfate

    Kazuyuki Sugahara;Tadahisa Mikami;Toru Uyama;Souhei Mizuguchi

  • Recent advances in the study of the biosynthesis and functions of sulfated glycosaminoglycans.

    Kazuyuki Sugahara;Hiroshi Kitagawa

  • Specific Molecular Interactions of Oversulfated Chondroitin Sulfate E with Various Heparin-binding Growth Factors IMPLICATIONS AS A PHYSIOLOGICAL BINDING PARTNER IN THE BRAIN AND OTHER TISSUES

    Sarama Sathyaseelan Deepa;Yuko Umehara;Shigeki Higashiyama;Nobuyuki Itoh

  • Composition of Perineuronal Net Extracellular Matrix in Rat Brain A DIFFERENT DISACCHARIDE COMPOSITION FOR THE NET-ASSOCIATED PROTEOGLYCANS

    Sarama Sathyaseelan Deepa;Daneila Carulli;Clare Galtrey;Kate Rhodes

  • Heparin and heparan sulfate biosynthesis.

    Kazuyuki Sugahara;Hiroshi Kitagawa

  • Chondroitin/dermatan sulfate in the central nervous system

    Kazuyuki Sugahara;Tadahisa Mikami

  • Potential therapeutic application of chondroitin sulfate/dermatan sulfate.

    Shuhei Yamada;Kazuyuki Sugahara

  • Microanalysis of glycosaminoglycan-derived oligosaccharides labeled with a fluorophore 2-aminobenzamide by high-performance liquid chromatography: application to disaccharide composition analysis and exosequencing of oligosaccharides.

    Akiko Kinoshita;Kazuyuki Sugahara

  • Oversulfated Chondroitin/Dermatan Sulfates Containing GlcAβ1/IdoAα1–3GalNAc(4,6-O-disulfate) Interact with L- and P-selectin and Chemokines

    Hiroto Kawashima;Kazuyuki Atarashi;Mayumi Hirose;Jun Hirose

  • Chondroitin proteoglycans are involved in cell division of Caenorhabditis elegans

    Souhei Mizuguchi;Toru Uyama;Hiroshi Kitagawa;Kazuko H. Nomura;Kazuko H. Nomura

  • The Tumor Suppressor EXT-like Gene EXTL2 Encodes an α1, 4-N-Acetylhexosaminyltransferase That TransfersN-Acetylgalactosamine and N-Acetylglucosamine to the Common Glycosaminoglycan-Protein Linkage Region THE KEY ENZYME FOR THE CHAIN INITIATION OF HEPARAN SULFATE

    Hiroshi Kitagawa;Hiromi Shimakawa;Kazuyuki Sugahara

  • Evolution of glycosaminoglycans: Comparative biochemical study.

    Shuhei Yamada;Kazuyuki Sugahara;Suat Özbek

  • Heparanase-enhanced shedding of syndecan-1 by myeloma cells promotes endothelial invasion and angiogenesis.

    Anurag Purushothaman;Toru Uyama;Fumi Kobayashi;Shuhei Yamada

  • Molecular cloning and expression of a human chondroitin synthase.

    Hiroshi Kitagawa;Toru Uyama;Kazuyuki Sugahara

  • Heparan/chondroitin sulfate biosynthesis. Structure and mechanism of human glucuronyltransferase I.

    Lars C. Pedersen;Kazunori Tsuchida;Hiroshi Kitagawa;Kazuyuki Sugahara

  • Chondroitin 6-sulphate synthesis is up-regulated in injured CNS, induced by injury-related cytokines and enhanced in axon-growth inhibitory glia.

    Francesca Properzi;Daniela Carulli;Richard A Asher;Elizabeth Muir

  • Chondroitin Sulfate Chains on Syndecan-1 and Syndecan-4 from Normal Murine Mammary Gland Epithelial Cells Are Structurally and Functionally Distinct and Cooperate with Heparan Sulfate Chains to Bind Growth Factors A NOVEL FUNCTION TO CONTROL BINDING OF MIDKINE, PLEIOTROPHIN, AND BASIC FIBROBLAST GROWTH FACTOR

    Sarama Sathyaseelan Deepa;Shuhei Yamada;Masahiro Zako;Olga Goldberger

  • The DSD-1 Carbohydrate Epitope Depends on Sulfation, Correlates with Chondroitin Sulfate D Motifs, and Is Sufficient to Promote Neurite Outgrowth

    Albrecht M. Clement;Satomi Nadanaka;Kimiko Masayama;Claudia Mandl

  • Characteristic hexasaccharide sequences in octasaccharides derived from shark cartilage chondroitin sulfate D with a neurite outgrowth promoting activity

    Satomi Nadanaka;Albrecht Clement;Kimiko Masayama;Andreas Faissner

  • Human tumor suppressor EXT gene family members EXTL1 and EXTL3 encode α1,4- N-acetylglucosaminyltransferases that likely are involved in heparan sulfate/ heparin biosynthesis

    Byung-Taek Kim;Hiroshi Kitagawa;Jun-ichi Tamura;Toshiyuki Saito

Frequent Co-Authors

Shuhei Yamada
Shuhei Yamada Meijo University
Hiroshi Kitagawa
Hiroshi Kitagawa Kobe Pharmaceutical University
Shimeru Kamihira
Shimeru Kamihira Nagasaki University
Andreas Faissner
Andreas Faissner Ruhr University Bochum
Toin H. van Kuppevelt
Toin H. van Kuppevelt Radboud University
Howard R. Morris
Howard R. Morris Imperial College London
Shohei Mitani
Shohei Mitani Tokyo Women's Medical University
Kanchugarakoppal S. Rangappa
Kanchugarakoppal S. Rangappa University of Mysore

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Exploring online education opens up a range of opportunities for those interested in Biology and Biochemistry careers. Students can get started in the healthcare field with a cma to lpn bridge program online, which enables medical assistants to advance as licensed practical nurses. These pathways offer flexible study options and are ideal for those balancing work and education.

For a broader foundation, online biology degrees provide accelerated programs that prepare graduates for research, laboratory, or technical roles. If your goals are more clinically oriented, you might consider asn online nursing programs. These degrees are a popular choice for those aiming to become registered nurses or enter advanced healthcare positions.

With the growing interest in nutrition and wellness, earning an online dietitian degree is another strong option. This path can lead to roles in clinical dietetics, public health, or health education. By pursuing these online degrees, students can tailor their studies to fit emerging trends and advance their science-based careers.

Best Scientists Citing Kazuyuki Sugahara

Trending Scientists

Recently Published Articles