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D-Index & Metrics

Molecular Biology

D-Index
58
Citations
12171
World Ranking
2087
National Ranking
167

Overview

Shohei Mitani is affiliated with Tokyo Women's Medical University in Japan, where their research focuses primarily on the fields of biochemistry, genetics, and molecular biology. Their work engages deeply with molecular biology, aging, genetics, physiology, and endocrine and autonomic systems. The scientist's predominant research themes include genetics, aging, and longevity in model organisms, along with CRISPR and genetic engineering methodologies.

Their published papers cover a range of topics related to mitochondrial function, RNA mechanisms, and genetic regulation. Notable recent publications include:

  • Defects in CISD-1, a mitochondrial iron-sulfur protein, lower glucose level and ATP production in Caenorhabditis elegans (2020) in Biomedical Journal
  • AMPK-FOXO-IP3R signaling pathway mediates neurological and developmental defects caused by mitochondrial DNA mutations (2023) in Proceedings of the National Academy of Sciences
  • Distinct pathways for export of silencing RNA in Caenorhabditis elegans systemic RNAi (2023) in iScience
  • Regulation of aging by balancing mitochondrial function and antioxidant levels (2022) in The Journal of Physiological Sciences
  • A small RNA system ensures accurate homologous pairing and unpaired silencing of meiotic chromosomes (2023) in The EMBO Journal

Frequent collaborators in their research include Sawako Yoshina, Yuji Suehiro, Katsufumi Dejima, Luna Izuhara, and Keita Yoshida.

Their research has been frequently published in venues such as PubMed, iScience, The Journal of Physiological Sciences, Scientific Reports, and Research Square.

  • PubMed
  • iScience
  • The Journal of Physiological Sciences
  • Scientific Reports
  • Research Square (Research Square)

Main scientific topics covered by Shohei Mitani include:

  • Genetics, Aging, and Longevity in Model Organisms
  • CRISPR and Genetic Engineering
  • RNA Research and Splicing
  • Circadian rhythm and melatonin
  • Mitochondrial Function and Pathology
  • RNA regulation and disease
  • Biochemical Acid Research Studies

Best Publications

  • Analysis of the C. elegans Argonaute Family Reveals that Distinct Argonautes Act Sequentially during RNAi

    Erbay Yigit;Pedro J. Batista;Yanxia Bei;Ka Ming Pang

  • Distinct argonaute-mediated 22G-RNA pathways direct genome surveillance in the C. elegans germline.

    Weifeng Gu;Masaki Shirayama;Darryl Conte Jr.;Jessica Vasale

  • The Argonaute CSR-1 and Its 22G-RNA Cofactors Are Required for Holocentric Chromosome Segregation

    Julie M. Claycomb;Pedro J. Batista;Ka Ming Pang;Weifeng Gu

  • Functional Proteomics Reveals the Biochemical Niche of C. elegans DCR-1 in Multiple Small-RNA-Mediated Pathways

    Thomas F. Duchaine;James A. Wohlschlegel;Scott Kennedy;Yanxia Bei

  • Large-scale screening for targeted knockouts in the caenorhabditis elegans genome

    Robert Barstead;Gary Moulder;Beth Cobb;Stephen Frazee

  • C. elegans Slit Acts in Midline, Dorsal-Ventral, and Anterior-Posterior Guidance via the SAX-3/Robo Receptor

    Joe C Hao;Timothy W Yu;Kazuko Fujisawa;Joseph G Culotti

  • Chondroitin proteoglycans are involved in cell division of Caenorhabditis elegans

    Souhei Mizuguchi;Toru Uyama;Hiroshi Kitagawa;Kazuko H. Nomura;Kazuko H. Nomura

  • Characterization of mutations induced by ethyl methanesulfonate, UV, and trimethylpsoralen in the nematode Caenorhabditis elegans.

    Keiko Gengyo-Ando;Shohei Mitani

  • HEN-1, a secretory protein with an LDL receptor motif, regulates sensory integration and learning in Caenorhabditis elegans.

    Takeshi Ishihara;Takeshi Ishihara;Yuichi Iino;Akiko Mohri;Ikue Mori

  • Cell corpse engulfment mediated by C. elegans phosphatidylserine receptor through CED-5 and CED-12.

    Xiaochen Wang;Yi Chun Wu;Valerie A. Fadok;Ming Chia Lee

  • Familial Parkinson Mutant α-Synuclein Causes Dopamine Neuron Dysfunction in Transgenic Caenorhabditis elegans

    Tomoki Kuwahara;Akihiko Koyama;Keiko Gengyo-Ando;Mayumi Masuda

  • A systematic RNAi screen reveals involvement of endocytic pathway in neuronal dysfunction in α-synuclein transgenic C. elegans

    Tomoki Kuwahara;Akihiko Koyama;Shingo Koyama;Shingo Koyama;Sawako Yoshina

  • C. elegans ced-13 can promote apoptosis and is induced in response to DNA damage

    B Schumacher;C Schertel;C Schertel;N Wittenburg;S Tuck

  • Mitochondrial endonuclease G mediates breakdown of paternal mitochondria upon fertilization

    Qinghua Zhou;Haimin Li;Hanzeng Li;Akihisa Nakagawa

  • Role of C. elegans TAT-1 Protein in Maintaining Plasma Membrane Phosphatidylserine Asymmetry

    Monica Darland-Ransom;Xiaochen Wang;Chun Ling Sun;James Mapes

  • Caspase-dependent conversion of Dicer ribonuclease into a death-promoting deoxyribonuclease.

    Akihisa Nakagawa;Yong Shi;Eriko Kage-Nakadai;Shohei Mitani

  • A CaMK cascade activates CRE-mediated transcription in neurons of Caenorhabditis elegans.

    Yoshishige Kimura;Ethan E. Corcoran;Koh Eto;Keiko Gengyo-Ando

  • Single/low-copy integration of transgenes in Caenorhabditis elegans using an ultraviolet trimethylpsoralen method

    Eriko Kage-Nakadai;Hiroyuki Kobuna;Osamu Funatsu;Muneyoshi Otori

  • Caenorhabditis elegans mboa-7, a member of the MBOAT family, is required for selective incorporation of polyunsaturated fatty acids into phosphatidylinositol.

    Hyeon Cheol Lee;Takao Inoue;Rieko Imae;Nozomu Kono

  • Caenorhabditis elegans drp-1 and fis-2 regulate distinct cell death execution pathways downstream of ced-3 and independent of ced-9

    David G. Breckenridge;Byung-Ho Kang;Byung-Ho Kang;David Kokel;Shohei Mitani

Frequent Co-Authors

Ding Xue
Ding Xue University of Colorado Boulder
Hiroyuki Arai
Hiroyuki Arai University of Tokyo
Craig C. Mello
Craig C. Mello University of Massachusetts Chan Medical School
Hiroshi Kitagawa
Hiroshi Kitagawa Kobe Pharmaceutical University
Kazuyuki Sugahara
Kazuyuki Sugahara Hokkaido University
Yuji Kohara
Yuji Kohara National Institute of Genetics
Toshiaki Katada
Toshiaki Katada Musashino University
Yasuo Ihara
Yasuo Ihara Doshisha University
Byung-Ho Kang
Byung-Ho Kang Chinese University of Hong Kong
Andrew D. Chisholm
Andrew D. Chisholm University of California, San Diego

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