What is he best known for?
The fields of study he is best known for:
Craig C. Mello mainly focuses on Genetics, RNA interference, RNA, Gene and Argonaute.
His RNA interference research includes themes of Gene silencing, RNA-dependent RNA polymerase and Small interfering RNA.
The RNA study combines topics in areas such as Regulation of gene expression and Cell biology.
His Cell biology research is multidisciplinary, relying on both Mutation, Molecular biology and Oligonucleotide, DNA.
As part of the same scientific family, Craig C. Mello usually focuses on Argonaute, concentrating on RasiRNA and intersecting with Piwi-interacting RNA.
His RNA silencing research is multidisciplinary, incorporating perspectives in DNA-directed RNA interference and Antisense RNA.
His most cited work include:
- Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans (12652 citations)
- Efficient gene transfer in C.elegans: extrachromosomal maintenance and integration of transforming sequences. (2613 citations)
- Genetic Inhibition by Double-Stranded RNA (1803 citations)
What are the main themes of his work throughout his whole career to date?
His primary scientific interests are in Genetics, Cell biology, Caenorhabditis elegans, Argonaute and RNA interference.
Craig C. Mello has included themes like Gene silencing, Asymmetric cell division, Cell division and Germline in his Cell biology study.
His research in Caenorhabditis elegans intersects with topics in Spindle apparatus, Genome, Cellular differentiation and Somatic cell.
His Argonaute study deals with Small RNA intersecting with RNA-binding protein.
His study in RNA interference is interdisciplinary in nature, drawing from both Molecular biology and Small interfering RNA.
Craig C. Mello has researched RNA silencing in several fields, including DNA-directed RNA interference, Antisense RNA, RNA-induced silencing complex and RNA-induced transcriptional silencing.
He most often published in these fields:
- Genetics (67.53%)
- Cell biology (62.34%)
- Caenorhabditis elegans (53.90%)
What were the highlights of his more recent work (between 2017-2021)?
- Cell biology (62.34%)
- Argonaute (46.75%)
- Gene silencing (31.82%)
In recent papers he was focusing on the following fields of study:
His primary areas of investigation include Cell biology, Argonaute, Gene silencing, Piwi-interacting RNA and Germline.
His studies in Cell biology integrate themes in fields like RNA, Small RNA, Mutant and Somatic cell.
The various areas that Craig C. Mello examines in his Argonaute study include Epigenetics and Caenorhabditis elegans.
His Caenorhabditis elegans study is concerned with the larger field of Genetics.
In his study, which falls under the umbrella issue of Piwi-interacting RNA, Nonsense-mediated decay, Coding region and Regulation of gene expression is strongly linked to Gene expression.
Many of his research projects under RNA interference are closely connected to mRNA surveillance with mRNA surveillance, tying the diverse disciplines of science together.
Between 2017 and 2021, his most popular works were:
- Robust Genome Editing with Short Single-Stranded and Long, Partially Single-Stranded DNA Donors in Caenorhabditis elegans. (106 citations)
- Robust Genome Editing with Short Single-Stranded and Long, Partially Single-Stranded DNA Donors in Caenorhabditis elegans. (106 citations)
- Identification of piRNA Binding Sites Reveals the Argonaute Regulatory Landscape of the C. elegans Germline. (95 citations)
In his most recent research, the most cited papers focused on:
His main research concerns Argonaute, Cell biology, Piwi-interacting RNA, Caenorhabditis elegans and Germline.
His Cell biology research incorporates themes from Gene silencing, DNA damage, Gene expression and Mutant.
His work deals with themes such as Nonsense-mediated decay, Regulation of gene expression and Coding region, which intersect with Gene silencing.
Caenorhabditis elegans is a subfield of Genetics that Craig C. Mello investigates.
His studies deal with areas such as Homologous chromosome, Mitosis, Topoisomerase, Embryo and DNA replication as well as Germline.
Craig C. Mello has researched Transposable element in several fields, including RNA and X chromosome, Dosage compensation.
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