World's Best Scientists 2026 revealed!
H. Robert Horvitz

H. Robert Horvitz

Award Badge
Molecular Biology
USA
2026

D-Index & Metrics

Molecular Biology

D-Index
140
Citations
96347
World Ranking
126
National Ranking
83

Research.com Recognitions

  • 2026 - Research.com Molecular Biology in United States Leader Award
  • 2025 - Research.com Molecular Biology in United States Leader Award
  • 2015 - Fellow, National Academy of Inventors
  • 2005 - Member of the European Academy of Sciences
  • 2002 - Gruber Prize in Genetics
  • 2002 - Nobel Prize for their discoveries concerning genetic regulation of organ development and programmed cell death'
  • 2001 - Genetics Society of America Medal
  • 1994 - Fellow of the American Academy of Arts and Sciences
  • 1991 - Member of the National Academy of Sciences
  • 1989 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

H. Robert Horvitz is affiliated with MIT in the United States and conducts research primarily in the field of Biochemistry, Genetics, and Molecular Biology. Their work focuses on various subfields including Molecular Biology, Aging, Cell Biology, Endocrine and Autonomic Systems, and Cellular and Molecular Neuroscience.

The research topics covered by Horvitz's publications include:

  • Genetics, Aging, and Longevity in Model Organisms
  • Circadian rhythm and melatonin
  • RNA Research and Splicing
  • Photosynthetic Processes and Mechanisms
  • CRISPR and Genetic Engineering
  • Mitochondrial Function and Pathology
  • Cellular transport and secretion

Recent papers authored or co-authored by Horvitz include:

  • C. elegans discriminates colors to guide foraging, 2021, Science
  • Replication stress promotes cell elimination by extrusion, 2021, Nature
  • H3.3 Nucleosome Assembly Mutants Display a Late-Onset Maternal Effect, 2020, Current Biology
  • An hourglass circuit motif transforms a motor program via subcellularly localized muscle calcium signaling and contraction, 2021, eLife
  • The pro-apoptotic function of the C. elegans BCL-2 homolog CED-9 requires interaction with the APAF-1 homolog CED-4, 2024, Science Advances

Frequent co-authors in Horvitz's research are:

  • Rita Droste
  • Steven R. Sando
  • D. Ghosh
  • Dong-Yeop Lee
  • Ji Na Kong

Horvitz's publications have appeared most frequently in the following venues:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Science
  • Nature
  • Current Biology
  • eLife

Among notable recognitions, Horvitz has received a number of awards and honors such as:

  • Fellow, National Academy of Inventors (2015)
  • Member of the European Academy of Sciences (2005)
  • Nobel Prize (2002) for discoveries concerning genetic regulation of organ development and programmed cell death
  • Gruber Prize in Genetics (2002)
  • Genetics Society of America Medal (2001)
  • Fellow of the American Academy of Arts and Sciences (1994)
  • Member of the National Academy of Sciences (1991)
  • Fellow of the American Association for the Advancement of Science (AAAS) (1989)

Best Publications

  • MicroRNA expression profiles classify human cancers

    Jun Lu;Gad Getz;Eric A. Miska;Eric A. Miska;Ezequiel Alvarez-Saavedra

  • The 21-nucleotide let-7 RNA regulates developmental timing in Caenorhabditis elegans

    Reinhart Bj;Slack Fj;Slack Fj;Basson M;Pasquinelli Ae

  • Post-embryonic cell lineages of the nematode, Caenorhabditis elegans

    J.E. Sulston;H.R. Horvitz

  • Mutations in the FUS/TLS gene on chromosome 16 cause familial amyotrophic lateral sclerosis.

    T. J. Kwiatkowski;D. A. Bosco;D. A. Bosco;A. L. LeClerc;A. L. LeClerc;E. Tamrazian

  • MicroRNA Expression in Zebrafish Embryonic Development

    Erno Wienholds;Wigard P. Kloosterman;Eric Miska;Ezequiel Alvarez-Saavedra

  • C. elegans cell survival gene ced-9 encodes a functional homolog of the mammalian proto-oncogene bcl-2

    Michael O. Hengartner;H.Robert Horvitz

  • C. elegans Locomotory Rate Is Modulated by the Environment through a Dopaminergic Pathway and by Experience through a Serotonergic Pathway

    Elizabeth R Sawin;Rajesh Ranganathan;H.Robert Horvitz

  • Odorant-selective genes and neurons mediate olfaction in C. elegans

    Cornelia I. Bargmann;Cornelia I. Bargmann;Erika Hartwieg;H. Robert Horvitz

  • Heterochronic mutants of the nematode Caenorhabditis elegans

    V Ambros;HR Horvitz

  • EGG-LAYING DEFECTIVE MUTANTS OF THE NEMATODE CAENORHABDITIS ELEGANS

    Carol Trent;Nancy Tsung;H. Robert Horvitz

  • The lin-41 RBCC gene acts in the C. elegans heterochronic pathway between the let-7 regulatory RNA and the LIN-29 transcription factor.

    Frank J. Slack;Michael Basson;Zhongchi Liu;Victor R. Ambros

  • Microarray analysis of microRNA expression in the developing mammalian brain

    Eric A Miska;Ezequiel Alvarez-Saavedra;Matthew Townsend;Matthew Townsend;Akira Yoshii

  • THE C. ELEGANS PROTEIN EGL-1 IS REQUIRED FOR PROGRAMMED CELL DEATH AND INTERACTS WITH THE BCL-2-LIKE PROTEIN CED-9

    Barbara Conradt;H.Robert Horvitz

  • Chemosensory neurons with overlapping functions direct chemotaxis to multiple chemicals in C. elegans

    Cornelia I. Bargmann;H.Robert Horvitz

  • CED-1 is a transmembrane receptor that mediates cell corpse engulfment in C. elegans.

    Zheng Zhou;Erika Hartwieg;H.Robert Horvitz

  • Mechanisms of asymmetric cell division: two Bs or not two Bs, that is the question.

    H.Robert Horvitz;Ira Herskowitz

  • Genetic control of programmed cell death in the Caenorhabditis elegans hermaphrodite germline.

    T.L. Gumienny;E. Lambie;E. Hartwieg;H.R. Horvitz

  • Mutations that lead to reiterations in the cell lineages of C. elegans

    Martin Chalfie;H.Robert Horvitz;John E. Sulston

  • The lin-12 locus specifies cell fates in caenorhabditis elegans

    Iva S. Greenwald;Paul W. Sternberg;H. Robert Horvitz

  • EGL-10 Regulates G Protein Signaling in the C. elegans Nervous System and Shares a Conserved Domain with Many Mammalian Proteins

    Michael R Koelle;H.Robert Horvitz

Frequent Co-Authors

Paul W. Sternberg
Paul W. Sternberg California Institute of Technology
Erik M. Jorgensen
Erik M. Jorgensen University of Utah
Yishi Jin
Yishi Jin University of California, San Diego
Junying Yuan
Junying Yuan Harvard University
Eric A. Miska
Eric A. Miska University of Cambridge
Iva Greenwald
Iva Greenwald Columbia University
Cornelia I. Bargmann
Cornelia I. Bargmann Rockefeller University
John Sulston
John Sulston Wellcome Sanger Institute
Roel A. Ophoff
Roel A. Ophoff University of California, Los Angeles

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