The scientist’s investigation covers issues in Genetics, Genome-wide association study, Single-nucleotide polymorphism, Schizophrenia and Genetic association. His Genetics study frequently draws connections to other fields, such as Psychosis. His Genome-wide association study research is multidisciplinary, incorporating perspectives in Amyotrophic lateral sclerosis, Quantitative trait locus, Genetic architecture, Allele and Genetic variation.
His work on Expression quantitative trait loci as part of general Single-nucleotide polymorphism study is frequently connected to IRF5, therefore bridging the gap between diverse disciplines of science and establishing a new relationship between them. His Schizophrenia study incorporates themes from Bipolar disorder, Neuroscience and Internal medicine, Disease. His work is dedicated to discovering how Bipolar disorder, Major depressive disorder are connected with Genetic heterogeneity and other disciplines.
Roel A. Ophoff mainly investigates Genetics, Genome-wide association study, Schizophrenia, Bipolar disorder and Internal medicine. His is doing research in Single-nucleotide polymorphism, Gene, Locus, Allele and Copy-number variation, both of which are found in Genetics. In his study, Expression quantitative trait loci is strongly linked to Quantitative trait locus, which falls under the umbrella field of Single-nucleotide polymorphism.
His work deals with themes such as Odds ratio, Amyotrophic lateral sclerosis, Disease, Linkage disequilibrium and Genetic association, which intersect with Genome-wide association study. His research in Schizophrenia intersects with topics in Psychosis, Case-control study, Neuroscience and Genomics. His Bipolar disorder research incorporates themes from Major depressive disorder, Clinical psychology and Brain size.
Roel A. Ophoff spends much of his time researching Bipolar disorder, Schizophrenia, Genetics, Genome-wide association study and Clinical psychology. His Bipolar disorder research includes elements of Pleiotropy, Mood, Internal medicine, Cohort and Prefrontal cortex. His Schizophrenia research integrates issues from Neuroscience, DNA methylation, Copy-number variation, Psychosis and Epigenetics.
His Genome-wide association study study combines topics in areas such as Eating disorders, Psychiatry, Etiology, Disease and Genetic association. Mental health, Demography, Pregnancy and Offspring is closely connected to Genetic heterogeneity in his research, which is encompassed under the umbrella topic of Genetic association. His Clinical psychology research includes themes of Meta-analysis, Cannabis use, Major depressive disorder and Tailored Intervention.
His primary areas of investigation include Schizophrenia, Bipolar disorder, Genetics, Genome-wide association study and Clinical psychology. He interconnects Methylation, Audiology, DNA methylation, Immunology and Neuroscience in the investigation of issues within Schizophrenia. His Bipolar disorder study combines topics from a wide range of disciplines, such as Major depressive disorder, Genetic heterogeneity, Psychosis and Genetic correlation.
In Genetic heterogeneity, Roel A. Ophoff works on issues like Mental health, which are connected to Genetic association. Gene and Multifactorial Inheritance are the primary areas of interest in his Genetics study. His Genome-wide association study research is multidisciplinary, incorporating elements of Genetic architecture, Brain morphometry, Tourette syndrome and Copy-number variation.
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Biological insights from 108 schizophrenia-associated genetic loci
Stephan Ripke;Stephan Ripke;Benjamin M. Neale;Benjamin M. Neale;Aiden Corvin;James T. R. Walters.
Nature (2014)
Familial Hemiplegic Migraine and Episodic Ataxia Type-2 Are Caused by Mutations in the Ca2+ Channel Gene CACNL1A4
Roel A. Ophoff;Gisela M. Terwindt;Monique N. Vergouwe;Ronald Van Eijk.
Cell (1996)
Large recurrent microdeletions associated with schizophrenia
Hreinn Stefansson;Dan Rujescu;Sven Cichon;Olli P. H. Pietilainen.
Nature (2008)
Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs
S. Hong Lee;Stephan Ripke;Stephan Ripke;Benjamin M. Neale;Benjamin M. Neale;Stephen V. Faraone.
Nature Genetics (2013)
Common variants conferring risk of schizophrenia
Hreinn Stefansson;Hreinn Stefansson;Roel A. Ophoff;Roel A. Ophoff;Roel A. Ophoff;Stacy Steinberg;Stacy Steinberg;Ole A. Andreassen.
Nature (2009)
Genome-wide association study identifies five new schizophrenia loci
Stephan Ripke;Alan R. Sanders;Kenneth S. Kendler;Douglas F. Levinson.
Nature Genetics (2011)
Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47.
Carl A. Anderson;Gabrielle Boucher;Charlie W. Lees;Andre Franke.
Nature Genetics (2011)
Modeling Linkage Disequilibrium Increases Accuracy of Polygenic Risk Scores
Bjarni J. Vilhjálmsson;Jian Yang;Hilary K. Finucane;Alexander Gusev.
American Journal of Human Genetics (2015)
Multiple common variants for celiac disease influencing immune gene expression
Patrick C. A. Dubois;Gosia Trynka;Lude Franke;Lude Franke;Karen A. Hunt.
Nature Genetics (2010)
Identification of common variants associated with human hippocampal and intracranial volumes
Jason L Stein;Sarah E Medland;Sarah E Medland;Alejandro Arias Vasquez;Alejandro Arias Vasquez;Derrek P Hibar.
Nature Genetics (2012)
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