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D-Index & Metrics

Genetics

D-Index
68
Citations
18043
World Ranking
2424
National Ranking
1091

Research.com Recognitions

  • 2005 - Fellow of the American Academy of Arts and Sciences
  • 2005 - Member of the National Academy of Sciences

Overview

Iva Greenwald is affiliated with Columbia University in the United States and contributes to the fields of Biochemistry, Genetics, and Molecular Biology with a focus on Molecular Biology, Aging, Physiology, Endocrine and Autonomic Systems, and Public Health, Environmental and Occupational Health. Their research spans topics such as Genetics, Aging, and Longevity in Model Organisms, CRISPR and Genetic Engineering, Pluripotent Stem Cells Research, Gene Regulatory Network Analysis, Retinal Development and Disorders, Spaceflight effects on biology, and Circadian rhythm and melatonin.

Their recent publications cover a range of research areas including gene expression regulation, signal transduction, and developmental biology. Key papers include:

  • "Floxed exon (Flexon): A flexibly positioned stop cassette for recombinase-mediated conditional gene expression," 2022, Proceedings of the National Academy of Sciences
  • "SALSA, a genetically encoded biosensor for spatiotemporal quantification of Notch signal transduction in vivo," 2022, Developmental Cell
  • "Negative feedback by conserved kinases patterns degradation of C. elegans Raf in vulval fate patterning," 2020, Development
  • "Evolutionary plasticity in the requirement for force exerted by ligand endocytosis to activate C. elegans Notch proteins," 2022, Current Biology
  • "Positive autoregulation of lag-1 in response to LIN-12 activation in cell fate decisions during C. elegans reproductive system development," 2020, Development

Frequent coauthors collaborating on these works include Justin M. Shaffer, Gary Struhl, Julia Wittes, Paul D. Langridge, and Jessica Yu Chan.

Greenwald's published work commonly appears in journals such as Development, Current Biology, G3 Genes Genomes Genetics, bioRxiv (Cold Spring Harbor Laboratory), and Proceedings of the National Academy of Sciences.

The scientist has been recognized with several honors, including being named a Fellow of the American Academy of Arts and Sciences and a Member of the National Academy of Sciences, both in 2005.

Best Publications

  • Presenilin is required for activity and nuclear access of Notch in Drosophila

    Gary Struhl;Iva Greenwald

  • Facilitation of lin-12-mediated signalling by sel-12, a Caenorhabditis elegans S182 Alzheimer's disease gene

    Diane Levitan;Iva Greenwald

  • LIN-12/Notch signaling: lessons from worms and flies

    Iva Greenwald

  • The lin-12 locus specifies cell fates in caenorhabditis elegans

    Iva S. Greenwald;Paul W. Sternberg;H. Robert Horvitz

  • Making a difference: The role of cell-cell interactions in establishing separate identities for equivalent cells

    Iva Greenwald;Gerald M. Rubin

  • Intrinsic activity of the lin-12 and Notch intracellular domains in vivo

    Gary Struhl;Kevin Fitzgerald;Kevin Fitzgerald;Iva Greenwald;Iva Greenwald

  • OrthoList: a compendium of C. elegans genes with human orthologs.

    Daniel D. Shaye;Iva Greenwald

  • ASSESSMENT OF NORMAL AND MUTANT HUMAN PRESENILIN FUNCTION IN CAENORHABDITIS ELEGANS

    Diane Levitan;Timothy G. Doyle;Denise Brousseau;Michael K. Lee

  • glp-1 and lin-12, genes implicated in distinct cell-cell interactions in C. elegans, encode similar transmembrane proteins.

    John Yochem;Iva Greenwald

  • The Caenorhabditis elegans lin-12 gene encodes a transmembrane protein with overall similarity to Drosophila Notch.

    John Yochem;Kathleen Weston;Kathleen Weston;Iva Greenwald

  • Genetic Analysis of Endocytosis in Caenorhabditis elegans: Coelomocyte Uptake Defective Mutants

    Hanna Fares;Hanna Fares;Iva Greenwald

  • Reciprocal changes in expression of the receptor lin-12 and its ligand lag-2 prior to commitment in a C. elegans cell fate decision

    Hilary A. Wilkinson;Kevin Fitzgerald;Iva Greenwald

  • sel-10, a negative regulator of lin-12 activity in Caenorhabditis elegans, encodes a member of the CDC4 family of proteins

    E. Jane Albert Hubbard;Guangyu Wu;Jan Kitajewski;Iva Greenwald

  • Crosstalk between the EGFR and LIN-12/Notch pathways in C. elegans vulval development.

    Andrew S. Yoo;Carlos Bais;Iva Greenwald

  • OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes.

    Woojin Kim;Ryan S Underwood;Iva Greenwald;Daniel D Shaye

  • Cell autonomy of lin-12 function in a cell fate decision in C. elegans.

    Geraldine Seydoux;Iva Greenwald

  • The Lateral Signal for LIN-12/Notch in C. elegans Vulval Development Comprises Redundant Secreted and Transmembrane DSL Proteins

    Ning Chen;Iva Greenwald

  • Regulation of endocytosis by CUP-5, the Caenorhabditis elegans mucolipin-1 homolog.

    Hanna Fares;Iva Greenwald

  • Membrane Topology of the C. elegans SEL-12 Presenilin

    Xiajun Li;Iva Greenwald

  • unc-93(e1500): A BEHAVIORAL MUTANT OF CAENORHABDITIS ELEGANS THAT DEFINES A GENE WITH A WILD-TYPE NULL PHENOTYPE

    Iva S. Greenwald;H. Robert Horvitz

Frequent Co-Authors

Geraldine Seydoux
Geraldine Seydoux Johns Hopkins University School of Medicine
Gary Struhl
Gary Struhl Columbia University
Paul W. Sternberg
Paul W. Sternberg California Institute of Technology
Barth D. Grant
Barth D. Grant Rutgers, The State University of New Jersey
Min Han
Min Han University of Colorado Boulder
Jan Kitajewski
Jan Kitajewski Columbia University
James R. Broach
James R. Broach Pennsylvania State University
Andrew Fire
Andrew Fire Stanford University
Gerald M. Rubin
Gerald M. Rubin Howard Hughes Medical Institute

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