What is he best known for?
The fields of study he is best known for:
His primary areas of investigation include Genetics, Saccharomyces cerevisiae, Biochemistry, Yeast and Cell biology.
His Gene, Origin of replication, Plasmid, Heterochromatin and Nucleosome investigations are all subjects of Genetics research.
His studies deal with areas such as Guanosine diphosphate, Guanine, Guanosine triphosphate and Activator as well as Saccharomyces cerevisiae.
Many of his research projects under Yeast are closely connected to Ras2 with Ras2, tying the diverse disciplines of science together.
In general Cell biology, his work in Signal transduction, Phosphatase and Autophagy-related protein 13 is often linked to Cancer metabolism linking many areas of study.
In his study, which falls under the umbrella issue of Signal transduction, Molecular biology, SH3 domain, Cyclase and Adenylate kinase is strongly linked to Protein kinase A.
His most cited work include:
- In yeast, RAS proteins are controlling elements of adenylate cyclase (839 citations)
- Transformation in yeast: Development of a hybrid cloning vector and isolation of the can1 gene (792 citations)
- Transcriptional silencing in yeast is associated with reduced nucleosome acetylation (747 citations)
What are the main themes of his work throughout his whole career to date?
James R. Broach mainly focuses on Genetics, Saccharomyces cerevisiae, Yeast, Biochemistry and Gene.
His study in Genetics concentrates on Plasmid, Chromatin, Locus, Origin of replication and Psychological repression.
His research in the fields of Fungal protein overlaps with other disciplines such as Ras2.
His Yeast research incorporates themes from Cell, G protein-coupled receptor and Function, Cell biology.
James R. Broach regularly ties together related areas like Molecular biology in his Biochemistry studies.
His studies link Computational biology with Gene.
He most often published in these fields:
- Genetics (37.76%)
- Saccharomyces cerevisiae (27.80%)
- Yeast (24.07%)
What were the highlights of his more recent work (between 2015-2021)?
- Genome (9.13%)
- Computational biology (11.20%)
- Gene (21.16%)
In recent papers he was focusing on the following fields of study:
Genome, Computational biology, Gene, Gene mapping and Genetics are his primary areas of study.
His Genome research incorporates elements of Als gene and Microbiology.
His Computational biology research incorporates themes from Structural variation, Bioinformatics, DNA Replication Timing, Chromatin and Chromosome conformation capture.
His Gene study combines topics from a wide range of disciplines, such as Follicular phase, DNA and Pathology.
His research on Genetics often connects related areas such as Inflammatory bowel disease.
His Whole genome sequencing research integrates issues from Ion homeostasis, Saccharomyces cerevisiae, Yeast, Reference genome and Genome editing.
Between 2015 and 2021, his most popular works were:
- Genome-wide Analyses Identify KIF5A as a Novel ALS Gene (215 citations)
- Integrative detection and analysis of structural variation in cancer genomes (126 citations)
- Genome-Wide Analyses Identify KIF5A as a Novel ALS Gene (83 citations)
In his most recent research, the most cited papers focused on:
His scientific interests lie mostly in Computational biology, Gene, Genome, Disease and Exome sequencing.
His Computational biology research is multidisciplinary, incorporating elements of CRISPR, Annotation, ENCODE and Functional genomics, Genomics.
His work on Missense mutation, Hereditary spastic paraplegia and Chromatin remodeling as part of general Gene study is frequently connected to MED1, therefore bridging the gap between diverse disciplines of science and establishing a new relationship between them.
He's looking at Missense mutation as part of his Genetics and Phenotype and Missense mutation study.
His biological study spans a wide range of topics, including Chromatin, Als gene and Chromosome conformation capture.
The various areas that James R. Broach examines in his Disease study include Microbiological culture, Cerebrospinal fluid and Microbiology.
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