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Medicine

D-Index
99
Citations
42523
World Ranking
8494
National Ranking
4384

Overview

Jeffrey S. Hyams is affiliated with the University of Connecticut in the United States. Their research primarily spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with a strong focus on subfields such as Genetics, Epidemiology, Surgery, Immunology, and Pediatrics, Perinatology and Child Health.

Their work concentrates extensively on topics related to Inflammatory Bowel Disease, Microscopic Colitis, Pharmaceutical studies and practices, Immunodeficiency and Autoimmune Disorders, Adolescent and Pediatric Healthcare, Helicobacter pylori-related gastroenterology studies, and Eosinophilic Esophagitis.

Hyams has contributed to numerous publications, with notable recent papers including:

  • Gut Microbiome Composition Is Associated With Future Onset of Crohn's Disease in Healthy First-Degree Relatives, 2023, Gastroenterology
  • Colonic Epithelial-Derived Selenoprotein P Is the Source for Antioxidant-Mediated Protection in Colitis-Associated Cancer, 2020, Gastroenterology
  • Real-World Infliximab Pharmacokinetic Study Informs an Electronic Health Record-Embedded Dashboard to Guide Precision Dosing in Children with Crohn's Disease, 2020, Clinical Pharmacology & Therapeutics
  • Ustekinumab in Paediatric Patients with Moderately to Severely Active Crohn's Disease: Pharmacokinetics, Safety, and Efficacy Results from UniStar, a Phase 1 Study, 2021, Journal of Crohn s and Colitis
  • Linking microbial genes to plasma and stool metabolites uncovers host-microbial interactions underlying ulcerative colitis disease course, 2024, Cell Host & Microbe

The scientist has frequently collaborated with other researchers including Lee A. Denson, Subra Kugathasan, Anne M. Griffiths, Joshua D. Noe, and Joel R. Rosh. Many of these collaborations have been prolific, as indicated by the count of joint publications.

Hyams' works are often published in prominent venues such as Gastroenterology, Journal of Crohn s and Colitis, Inflammatory Bowel Diseases, Journal of Pediatric Gastroenterology and Nutrition, and bioRxiv (Cold Spring Harbor Laboratory).

This body of research highlights a concentrated effort on gastrointestinal diseases with an emphasis on pediatric populations and immunological factors, supported by studies spanning clinical pharmacology, genetics, and disease epidemiology.

Best Publications

  • The Treatment-Naive Microbiome in New-Onset Crohn’s Disease

    Dirk Gevers;Subra Kugathasan;Lee A. Denson;Yoshiki Vázquez-Baeza

  • Childhood Functional Gastrointestinal Disorders: Child/Adolescent

    Andrée Rasquin;Carlo Di Lorenzo;David Forbes;Ernesto Guiraldes

  • Pediatric modification of the Montreal classification for inflammatory bowel disease: the Paris classification.

    Arie Levine;Anne Griffiths;James Markowitz;David C Wilson

  • Development and validation of a pediatric Crohn's disease activity index.

    Hyams Js;Ferry Gd;Mandel Fs;Gryboski Jd

  • Development and Validation of a Pediatric Crohnʼs Disease Activity Index

    Jeffrey S. Hyams;George D. Ferry;Francine S. Mandel;Joyce D. Gryboski

  • Functional Disorders: Children and Adolescents.

    Hyams Js;Di Lorenzo C;Saps M;Shulman Rj

  • Development, Validation, and Evaluation of a Pediatric Ulcerative Colitis Activity Index: A Prospective Multicenter Study

    Dan Turner;Anthony R. Otley;David Mack;Jeffrey Hyams

  • Induction and Maintenance Infliximab Therapy for the Treatment of Moderate-to-Severe Crohn’s Disease in Children

    Jeffrey Hyams;Wallace Crandall;Subra Kugathasan;Anne Griffiths

  • Childhood functional gastrointestinal disorders

    A Rasquin-Weber;P E Hyman;S Cucchiara;D R Fleisher

  • Single-Cell Analysis of Crohn's Disease Lesions Identifies a Pathogenic Cellular Module Associated with Resistance to Anti-TNF Therapy.

    Jerome C. Martin;Christie Chang;Gilles Boschetti;Ryan Ungaro

  • Abdominal pain and irritable bowel syndrome in adolescents: A community-based study

    Jeffrey S. Hyams;Georgine Burke;Patricia M. Davis;Barbara Rzepski

  • Prediction of complicated disease course for children newly diagnosed with Crohn's disease: a multicentre inception cohort study

    Subra Kugathasan;Lee A. Denson;Thomas D. Walters;Mi Ok Kim

  • Differentiating ulcerative colitis from Crohn disease in children and young adults: report of a working group of the North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition and the Crohn's and Colitis Foundation of America.

    Athos Bousvaros

  • Pediatric Crohn disease patients exhibit specific ileal transcriptome and microbiome signature

    Yael Haberman;Timothy L. Tickle;Phillip J. Dexheimer;Mi-Ok Kim

  • Chronic Abdominal Pain In Children: a Technical Report of the American Academy of Pediatrics and the North American Society for Pediatric Gastroenterology, Hepatology and Nutrition

    Carlo Di Lorenzo;Richard B Colletti;Horald P Lehmann;John T Boyle

  • Evaluation of the pediatric crohn disease activity index: a prospective multicenter experience.

    Jeffrey Hyams;James Markowitz;Anthony Otley;Joel Rosh

  • Hepatosplenic T-cell lymphoma in adolescents and young adults with Crohn's disease: a cautionary tale?

    Joel R. Rosh;Thomas Gross;Petar Mamula;Anne Griffiths

  • Safety and Efficacy of Adalimumab for Moderate to Severe Crohn's Disease in Children

    Jeffrey S. Hyams;Anne Griffiths;James Markowitz;Robert N. Baldassano

  • Appraisal of the pediatric ulcerative colitis activity index (PUCAI)

    Dan Turner;Dan Turner;Jeffrey Hyams;James Markowitz;Trudy Lerer

  • Functional gastrointestinal disorders.

    Jeffrey S. Hyams

Frequent Co-Authors

Anne M. Griffiths
Anne M. Griffiths University of Toronto
Subra Kugathasan
Subra Kugathasan Emory University
David R. Mack
David R. Mack University of Ottawa
Lee A. Denson
Lee A. Denson Cincinnati Children's Hospital Medical Center
Robert N. Baldassano
Robert N. Baldassano Children's Hospital of Philadelphia
Marla Dubinsky
Marla Dubinsky Icahn School of Medicine at Mount Sinai
Dan Turner
Dan Turner Hebrew University of Jerusalem
Frank M. Ruemmele
Frank M. Ruemmele Necker-Enfants Malades Hospital
Jonathan P. Evans
Jonathan P. Evans University of Western Australia
Bruce J. Aronow
Bruce J. Aronow Cincinnati Children's Hospital Medical Center

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