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Subra Kugathasan

Subra Kugathasan

D-Index & Metrics

Medicine

D-Index
93
Citations
45972
World Ranking
10676
National Ranking
5490

Overview

Subra Kugathasan is affiliated with Emory University in the United States and has an extensive publication record primarily in the fields of Medicine and Biochemistry, Genetics and Molecular Biology. Their research focuses heavily on inflammatory bowel disease (IBD) and related gastrointestinal and immunological conditions.

The scientist has contributed to numerous research papers, with notable recent works including:

  • A myeloid-stromal niche and gp130 rescue in NOD2-driven Crohn's disease, 2021, Nature
  • Common and Rare Variant Prediction and Penetrance of IBD in a Large, Multi-ethnic, Health System-based Biobank Cohort, 2020, Gastroenterology
  • DUOX2 variants associate with preclinical disturbances in microbiota-immune homeostasis and increased inflammatory bowel disease risk, 2021, Journal of Clinical Investigation
  • Linking microbial genes to plasma and stool metabolites uncovers host-microbial interactions underlying ulcerative colitis disease course, 2024, Cell Host & Microbe
  • Predicting disease course in ulcerative colitis using stool proteins identified through an aptamer-based screen, 2021, Nature Communications

Their frequent co-authors include Lee A. Denson, Jeffrey S. Hyams, Suresh Venkateswaran, Vasantha L. Kolachala, and David J. Cutler. These collaborations reflect a network deeply engaged in research related to gastrointestinal diseases and immunological responses.

Subra Kugathasan has published extensively in several specialized venues, with the most frequent being:

  • Gastroenterology
  • Inflammatory Bowel Diseases
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Journal of Crohn's and Colitis
  • UNC Libraries

The main subfields of their study include Genetics, Epidemiology, Molecular Biology, Immunology, and Surgery. These areas highlight a multidisciplinary approach aimed at understanding complex biological, immunological, and clinical aspects of disease.

The primary topics of Subra Kugathasan's research reflect focus areas in gastroenterology and immunology, including:

  • Inflammatory Bowel Disease
  • Microscopic Colitis
  • Helicobacter pylori-related gastroenterology studies
  • Immunodeficiency and Autoimmune Disorders
  • IL-33, ST2, and ILC Pathways
  • Gut microbiota and health
  • Autoimmune and Inflammatory Disorders

Best Publications

  • Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease

    Luke Jostins;Stephan Ripke;Rinse K Weersma;Richard H Duerr

  • The Treatment-Naive Microbiome in New-Onset Crohn’s Disease

    Dirk Gevers;Subra Kugathasan;Lee A. Denson;Yoshiki Vázquez-Baeza

  • Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci

    Andre Franke;Dermot P B McGovern;Jeffrey C. Barrett;Kai Wang

  • Multi-omics of the gut microbial ecosystem in inflammatory bowel diseases.

    Jason Lloyd-Price;Jason Lloyd-Price;Cesar Arze;Ashwin N. Ananthakrishnan;Melanie Schirmer;Melanie Schirmer

  • Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47.

    Carl A. Anderson;Gabrielle Boucher;Charlie W. Lees;Andre Franke

  • A structural variation reference for medical and population genetics

    Ryan L Collins;Ryan L Collins;Harrison Brand;Harrison Brand;Konrad J Karczewski;Konrad J Karczewski;Xuefang Zhao;Xuefang Zhao

  • Induction and Maintenance Infliximab Therapy for the Treatment of Moderate-to-Severe Crohn’s Disease in Children

    Jeffrey Hyams;Wallace Crandall;Subra Kugathasan;Anne Griffiths

  • Single-Cell Analysis of Crohn's Disease Lesions Identifies a Pathogenic Cellular Module Associated with Resistance to Anti-TNF Therapy.

    Jerome C. Martin;Christie Chang;Gilles Boschetti;Ryan Ungaro

  • A novel Ruminococcus gnavus clade enriched in inflammatory bowel disease patients

    Andrew Brantley Hall;Andrew Brantley Hall;Moran Yassour;Moran Yassour;Jenny Sauk;Jenny Sauk;Ashley Garner;Ashley Garner

  • Epidemiologic and clinical characteristics of children with newly diagnosed inflammatory bowel disease in Wisconsin: a statewide population-based study.

    Subra Kugathasan;Robert H Judd;Raymond G Hoffmann;Janice Heikenen

  • Prediction of complicated disease course for children newly diagnosed with Crohn's disease: a multicentre inception cohort study

    Subra Kugathasan;Lee A. Denson;Thomas D. Walters;Mi Ok Kim

  • Differentiating ulcerative colitis from Crohn disease in children and young adults: report of a working group of the North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition and the Crohn's and Colitis Foundation of America.

    Athos Bousvaros

  • Common variants at five new loci associated with early-onset inflammatory bowel disease.

    Marcin Imielinski;Robert N. Baldassano;Anne Griffiths;Richard K. Russell

  • Pediatric Crohn disease patients exhibit specific ileal transcriptome and microbiome signature

    Yael Haberman;Timothy L. Tickle;Phillip J. Dexheimer;Mi-Ok Kim

  • Dynamics of metatranscription in the inflammatory bowel disease gut microbiome

    Melanie Schirmer;Melanie Schirmer;Eric A. Franzosa;Eric A. Franzosa;Jason Lloyd-Price;Jason Lloyd-Price;Lauren J. McIver;Lauren J. McIver

  • A randomized, double-blind trial of lactobacillus GG versus placebo in addition to standard maintenance therapy for children with Crohn's disease

    Athos Bousvaros;Stefano Guandalini;Robert N Baldassano;Christine Botelho

  • Genetics of Inflammatory Bowel Diseases

    Dermot McGovern;Subramaniam Kugathasan;Judy H. Cho

  • Loci on 20q13 and 21q22 are associated with pediatric-onset inflammatory bowel disease

    Subra Kugathasan;Robert N Baldassano;Jonathan P Bradfield;Patrick M A Sleiman

  • Safety, tolerability, and clinical response after fecal transplantation in children and young adults with ulcerative colitis.

    Sachin Kunde;Angela Pham;Sarah Bonczyk;Teri Crumb

  • Evaluation of the pediatric crohn disease activity index: a prospective multicenter experience.

    Jeffrey Hyams;James Markowitz;Anthony Otley;Joel Rosh

Frequent Co-Authors

Jeffrey S. Hyams
Jeffrey S. Hyams University of Connecticut
Anne M. Griffiths
Anne M. Griffiths University of Toronto
Lee A. Denson
Lee A. Denson Cincinnati Children's Hospital Medical Center
Robert N. Baldassano
Robert N. Baldassano Children's Hospital of Philadelphia
David R. Mack
David R. Mack University of Ottawa
Marla Dubinsky
Marla Dubinsky Icahn School of Medicine at Mount Sinai
Ramnik J. Xavier
Ramnik J. Xavier Broad Institute
Bruce J. Aronow
Bruce J. Aronow Cincinnati Children's Hospital Medical Center
Judy H. Cho
Judy H. Cho Icahn School of Medicine at Mount Sinai
Greg Gibson
Greg Gibson Georgia Institute of Technology

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