Elena I. Rugarli

Overview

Best Publications

• The i-AAA protease YME1L and OMA1 cleave OPA1 to balance mitochondrial fusion and fission

  Ruchika Anand;Timothy Wai;Michael J. Baker;Nikolay Kladt

  772
  Citations

• Regulation of OPA1 processing and mitochondrial fusion by m-AAA protease isoenzymes and OMA1

  Sarah Ehses;Ines Raschke;Giuseppe Mancuso;Andrea Bernacchia

  596
  Citations

• Mitochondrial quality control: a matter of life and death for neurons

  Elena I Rugarli;Thomas Langer;Thomas Langer

  449
  Citations

• The m-AAA Protease Defective in Hereditary Spastic Paraplegia Controls Ribosome Assembly in Mitochondria

  Mark Nolden;Sarah Ehses;Mirko Koppen;Andrea Bernacchia

  442
  Citations

• Opitz G/BBB syndrome, a defect of midline development, is due to mutations in a new RING finger gene on Xp22

  Nandita A. Quaderi;Susann Schweiger;Karin Gaudenz;Brunella Franco

  409
  Citations

• Axonal degeneration in paraplegin-deficient mice is associated with abnormal mitochondria and impairment of axonal transport

  Fatima Ferreirinha;Angelo Quattrini;Marinella Pirozzi;Valentina Valsecchi

  358
  Citations

• Spastin, the protein mutated in autosomal dominant hereditary spastic paraplegia, is involved in microtubule dynamics

  Alessia Errico;Andrea Ballabio;Elena I. Rugarli

  306
  Citations

• DNAJC19, a mitochondrial cochaperone associated with cardiomyopathy, forms a complex with prohibitins to regulate cardiolipin remodeling.

  Ricarda Richter-Dennerlein;Anne Korwitz;Mathias Haag;Takashi Tatsuta

  231
  Citations

• Whole-Exome Sequencing Identifies Homozygous AFG3L2 Mutations in a Spastic Ataxia-Neuropathy Syndrome Linked to Mitochondrial m-AAA Proteases

  Tyler Mark Pierson;David Adams;Florian Bonn;Paola Martinelli

  224
  Citations

• Tissue-specific loss of DARS2 activates stress responses independently of respiratory chain deficiency in the heart.

  Sukru Anil Dogan;Claire Pujol;Priyanka Maiti;Alexandra Kukat

  218
  Citations

• Variable and Tissue-Specific Subunit Composition of Mitochondrial m-AAA Protease Complexes Linked to Hereditary Spastic Paraplegia

  Mirko Koppen;Metodi D. Metodiev;Giorgio Casari;Elena I. Rugarli

  212
  Citations

• OPA1 Processing Reconstituted in Yeast Depends on the Subunit Composition of the m-AAA Protease in Mitochondria

  Stéphane Duvezin-Caubet;Mirko Koppen;Johannes Wagener;Michael Zick

  208
  Citations

• Expression pattern of the Kallmann syndrome gene in the olfactory system suggests a role in neuronal targeting

  Elena I. Rugarli;Beat Lutz;Shigeru C. Kuratani;Stefan Wawersik

  186
  Citations

• The product of X-linked Kallmann's syndrome gene (KAL1) affects the migratory activity of gonadotropin-releasing hormone (GnRH)-producing neurons

  Anna Cariboni;Federica Pimpinelli;Sophia Colamarino;Roberta Zaninetti

  183
  Citations

• The m-AAA Protease Associated with Neurodegeneration Limits MCU Activity in Mitochondria

  Tim König;Simon E. Tröder;Kavya Bakka;Anne Korwitz

  182
  Citations

• Loss of Prohibitin Membrane Scaffolds Impairs Mitochondrial Architecture and Leads to Tau Hyperphosphorylation and Neurodegeneration

  Carsten Merkwirth;Paola Martinelli;Anne Korwitz;Michela Morbin

  173
  Citations

• Spastin interacts with the centrosomal protein NA14, and is enriched in the spindle pole, the midbody and the distal axon

  Alessia Errico;Pamela Claudiani;Marilena D'Addio;Elena I. Rugarli

  171
  Citations

• Spastin subcellular localization is regulated through usage of different translation start sites and active export from the nucleus

  Pamela Claudiani;Elena Riano;Alessia Errico;Gennaro Andolfi

  156
  Citations

• Loss of OMA1 delays neurodegeneration by preventing stress-induced OPA1 processing in mitochondria

  Anne Korwitz;Carsten Merkwirth;Ricarda Richter-Dennerlein;Simon E. Tröder

  138
  Citations

• A gene from the Xp22.3 region shares homology with voltage-gated chloride channels

  Marjon A.van Slegtenhorst;Maria T.Bassl;Gluseppe Borsanil;Martin C. Wapenaar

  136
  Citations