Michael Kracht

Overview

Best Publications

• Multiple control of interleukin-8 gene expression

  Elke Hoffmann;Oliver Dittrich-Breiholz;Helmut Holtmann;Michael Kracht

  1296
  Citations

• Interleukin-1 (IL-1) Pathway

  Axel Weber;Peter Wasiliew;Michael Kracht

  1013
  Citations

• The p38 MAP kinase pathway signals for cytokine-induced mRNA stabilization via MAP kinase-activated protein kinase 2 and an AU-rich region-targeted mechanism

  Reinhard Winzen;Michael Kracht;Birgit Ritter;Arno Wilhelm

  998
  Citations

• Constitutive and interleukin-1-inducible phosphorylation of p65 NF-{kappa}B at serine 536 is mediated by multiple protein kinases including I{kappa}B kinase (IKK)-{alpha}, IKK{beta}, IKK{epsilon}, TRAF family member-associated (TANK)-binding kinase 1 (TBK1), and an unknown kinase and couples p65 to TATA-binding protein-associated factor II31-mediated interleukin-8 transcription.

  Holger Buss;Anneke Dörrie;M. Lienhard Schmitz;Elke Hoffmann

  521
  Citations

• Targeting innate immunity protein kinase signalling in inflammation.

  Matthias Gaestel;Alexey Kotlyarov;Michael Kracht

  446
  Citations

• The Interleukin-1 Receptor Accessory Protein (IL-1RAcP) Is Essential for IL-1-induced Activation of Interleukin-1 Receptor-associated Kinase (IRAK) and Stress-activated Protein Kinases (SAP Kinases)

  Holger Wesche;Christian Korherr;Michael Kracht;Werner Falk

  444
  Citations

• Induction of Interleukin-8 Synthesis Integrates Effects on Transcription and mRNA Degradation from at Least Three Different Cytokine- or Stress-Activated Signal Transduction Pathways

  Helmut Holtmann;Reinhard Winzen;Pamela Holland;Solveig Eickemeier

  434
  Citations

• IL-1 family nomenclature

  Charles Dinarello;William Arend;John Sims;Dirk Smith

  413
  Citations

• IκB-independent control of NF-κB activity by modulatory phosphorylations

  M.Lienhard Schmitz;Susanne Bacher;Michael Kracht

  351
  Citations

• NF‐κB: A Multifaceted Transcription Factor Regulated at Several Levels

  M. Lienhard Schmitz;Ivan Mattioli;Holger Buss;Michael Kracht

  344
  Citations

• Phosphorylation of Serine 468 by GSK-3β Negatively Regulates Basal p65 NF-κB Activity

  Holger Buss;Anneke Dörrie;M. Lienhard Schmitz;Ronald Frank

  333
  Citations

• Transcriptional and post-transcriptional control of gene expression in inflammation.

  Michael Kracht;Jeremy Saklatvala

  324
  Citations

• NFκB activation by Fas is mediated through FADD, caspase-8, and RIP and is inhibited by FLIP

  Sebastian Kreuz;Daniela Siegmund;Jost-Julian Rumpf;Dierk Samel

  315
  Citations

• Protein synthesis inhibitors reveal differential regulation of mitogen-activated protein kinase and stress-activated protein kinase pathways that converge on Elk-1.

  Raymund Zinck;Michael A. Cahill;Michael Kracht;Christoph Sachsenmaier

  308
  Citations

• Transient and selective NF-kappa B p65 serine 536 phosphorylation induced by T cell costimulation is mediated by I kappa B kinase beta and controls the kinetics of p65 nuclear import.

  Ivan Mattioli;Andrea Sebald;Cyril Bucher;Roch-Philippe Charles

  289
  Citations

• The mitogen-activated protein kinase (MAPK)-activated protein kinases MK2 and MK3 cooperate in stimulation of tumor necrosis factor biosynthesis and stabilization of p38 MAPK.

  N. Ronkina;A. Kotlyarov;O. Dittrich-Breiholz;M. Kracht

  253
  Citations

• Caspase-8 deficiency in epidermal keratinocytes triggers an inflammatory skin disease

  Andrew Kovalenko;Jin-Chul Kim;Tae-Bong Kang;Akhil Rajput

  233
  Citations

• Influenza virus-induced AP-1-dependent gene expression requires activation of the JNK signaling pathway.

  Stephan Ludwig;Christina Ehrhardt;Elisabeth R. Neumeier;Michael Kracht

  231
  Citations

• Interleukin-1β (IL-1β) Processing Pathway

  Axel Weber;Peter Wasiliew;Michael Kracht

  197
  Citations

• Phosphorylation of NF-κB p65 at Ser468 controls its COMMD1-dependent ubiquitination and target gene-specific proteasomal elimination

  Hui Geng;Tobias Wittwer;Oliver Dittrich‐Breiholz;Michael Kracht

  189
  Citations