His primary areas of study are Molecular biology, Endocrinology, Internal medicine, MAP2K7 and Tumor necrosis factor alpha. His Molecular biology research is multidisciplinary, incorporating elements of Gene expression, Transcription factor, Biochemistry, Protein phosphorylation and Cell biology. His work carried out in the field of Endocrinology brings together such families of science as Interleukin and Cytokine.
His Internal medicine research is multidisciplinary, relying on both Zymosan, Phospholipase and Arachidonic acid. His study in MAP2K7 is interdisciplinary in nature, drawing from both Mitogen-activated protein kinase kinase, Cyclin-dependent kinase 9, ASK1 and MAP kinase kinase kinase. His Tumor necrosis factor alpha research incorporates elements of Cyclooxygenase, Receptor and Respiratory burst.
His primary scientific interests are in Biochemistry, Molecular biology, Cell biology, Internal medicine and Endocrinology. His research in Molecular biology intersects with topics in MAP kinase kinase kinase, Protein kinase A, Mitogen-activated protein kinase kinase, Receptor and MAP2K7. His study looks at the intersection of MAP2K7 and topics like c-Raf with ASK1.
His Endocrinology study integrates concerns from other disciplines, such as Interleukin and Cell growth. His Tumor necrosis factor alpha research includes themes of Cyclooxygenase and Cytokine. Klaus Resch combines subjects such as Platelet-derived growth factor and Growth factor with his study of Mesangial cell.
His primary areas of investigation include Molecular biology, Cell biology, Biochemistry, Chromatography and Phosphorylation. His work deals with themes such as MAP2K7, Cyclin-dependent kinase 2, Mitogen-activated protein kinase kinase, Untranslated region and MAP kinase kinase kinase, which intersect with Molecular biology. His Cell biology study combines topics in areas such as Promoter and Death domain.
The concepts of his Biochemistry study are interwoven with issues in Stimulation, Colchicine and Lymphocyte. As a part of the same scientific family, he mostly works in the field of Phosphorylation, focusing on Kinase and, on occasion, Consensus site, IκBα and Transactivation. In his study, Endocrinology is strongly linked to Platelet-derived growth factor receptor, which falls under the umbrella field of Mesangial cell.
His scientific interests lie mostly in Molecular biology, Kinase, Protein kinase A, Cell biology and Chromatography. His Molecular biology study incorporates themes from Epidermal growth factor, Chromatin immunoprecipitation, Transcription factor, IκBα and Protein phosphorylation. In his work, Protein phosphatase 2 and Effector is strongly intertwined with Phosphorylation, which is a subfield of Kinase.
His studies deal with areas such as Tumor necrosis factor alpha, Binding protein, Protein subunit and Immunoprecipitation as well as Cell biology. His Chromatography research is multidisciplinary, incorporating perspectives in Whole blood and Everolimus. His Cyclin-dependent kinase 9 research is within the category of Biochemistry.
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The p38 MAP kinase pathway signals for cytokine-induced mRNA stabilization via MAP kinase-activated protein kinase 2 and an AU-rich region-targeted mechanism
Reinhard Winzen;Michael Kracht;Birgit Ritter;Arno Wilhelm.
The EMBO Journal (1999)
Human fibroblasts release reactive oxygen species in response to interleukin-1 or tumour necrosis factor-alpha.
B Meier;H H Radeke;S Selle;M Younes.
Biochemical Journal (1989)
Constitutive and interleukin-1-inducible phosphorylation of p65 NF-{kappa}B at serine 536 is mediated by multiple protein kinases including I{kappa}B kinase (IKK)-{alpha}, IKK{beta}, IKK{epsilon}, TRAF family member-associated (TANK)-binding kinase 1 (TBK1), and an unknown kinase and couples p65 to TATA-binding protein-associated factor II31-mediated interleukin-8 transcription.
Holger Buss;Anneke Dörrie;M. Lienhard Schmitz;Elke Hoffmann.
Journal of Biological Chemistry (2004)
Induction of Interleukin-8 Synthesis Integrates Effects on Transcription and mRNA Degradation from at Least Three Different Cytokine- or Stress-Activated Signal Transduction Pathways
Helmut Holtmann;Reinhard Winzen;Pamela Holland;Solveig Eickemeier.
Molecular and Cellular Biology (1999)
The Interleukin-1 Receptor Accessory Protein (IL-1RAcP) Is Essential for IL-1-induced Activation of Interleukin-1 Receptor-associated Kinase (IRAK) and Stress-activated Protein Kinases (SAP Kinases)
Holger Wesche;Christian Korherr;Michael Kracht;Werner Falk.
Journal of Biological Chemistry (1997)
Interleukin 1-α and tumor necrosis factor-α induce oxygen radical production in mesangial cells
Heinfried H. Radeke;Beate Meier;Nicholas Topley;Jürgen Flöge.
Kidney International (1990)
Phosphorylation of Serine 468 by GSK-3β Negatively Regulates Basal p65 NF-κB Activity
Holger Buss;Anneke Dörrie;M. Lienhard Schmitz;Ronald Frank.
Journal of Biological Chemistry (2004)
Quantification of antiretroviral drugs in dried blood spot samples by means of liquid chromatography/tandem mass spectrometry
Therese Koal;Heike Burhenne;Regina Römling;Michal Svoboda.
Rapid Communications in Mass Spectrometry (2005)
Interleukin-1-induced cyclooxygenase 2 expression is suppressed by cyclosporin A in rat mesangial cells
Michael Martin;Detlef Neumann;Torsten Hoff;Klaus Resch.
Kidney International (1994)
Macrophage cytotoxicity: interleukin 1 as a mediator of tumor cytostasis.
D Lovett;B Kozan;M Hadam;K Resch.
Journal of Immunology (1986)
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