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Reinhold E. Schmidt

Reinhold E. Schmidt

D-Index & Metrics

Immunology

D-Index
99
Citations
33370
World Ranking
757
National Ranking
47

Medicine

D-Index
99
Citations
33830
World Ranking
8637
National Ranking
489

Overview

Reinhold E. Schmidt was affiliated with Hannover Medical School in Germany. Their research spanned primarily across immunology and microbiology, with a significant focus on subfields such as immunology, genetics, cancer research, molecular biology, and virology.

Their contributions addressed key topics in immunodeficiency and autoimmune disorders, NF-κB signaling pathways, immune cell function and interaction, chronic lymphocytic leukemia research, interferon and immune responses, blood disorders and treatments, and RNA regulation and disease.

Schmidt's publication record included work in several scientific venues. Notable among these were Frontiers in Immunology, where they had multiple publications, along with single contributions in the Journal of Allergy and Clinical Immunology, Cellular and Molecular Immunology, Advances in Immunology, and Annals of the Rheumatic Diseases.

Their recent papers included:

  • Characterization of the clinical and immunologic phenotype and management of 157 individuals with 56 distinct heterozygous NFKB1 mutations (2020, Journal of Allergy and Clinical Immunology)
  • Cellular and molecular mechanisms breaking immune tolerance in inborn errors of immunity (2021, Cellular and Molecular Immunology)
  • Homeostatic and pathogenic roles of PI3Kδ in the human immune system (2020, Advances in Immunology)
  • High frequency of variants in genes associated with primary immunodeficiencies in patients with rheumatic diseases with secondary hypogammaglobulinaemia (2020, Annals of the Rheumatic Diseases)
  • Peripheral Blood Lymphocyte Phenotype Differentiates Secondary Antibody Deficiency in Rheumatic Disease from Primary Antibody Deficiency (2020, Journal of Clinical Medicine)

Frequent collaborators included Faranaz Atschekzei, Georgios Sogkas, Natalia Dubrowinskaja, Ignatius Ryan Adriawan, and Torsten Witte. These coauthors contributed multiple joint publications, reflecting sustained collaborative research efforts.

Across their research career, Schmidt produced work diffusely intersecting immunology with molecular and genetic studies, focusing particularly on mechanisms of immune dysfunction and disease. Their interests encompassed clinical immunology as well as molecular pathways, including NF-κB signaling and PI3K delta roles in immune regulation.

Reinhold E. Schmidt's scientific output provided insights into disease mechanisms, immune regulation, and genetic underpinnings of immune disorders, contributing to several fields of biomedical research until their passing.

Best Publications

  • The EUROclass trial: defining subgroups in common variable immunodeficiency

    Claudia Wehr;Teemu Kivioja;Christian Schmitt;Berne Ferry

  • New loci associated with kidney function and chronic kidney disease

    Anna Köttgen;Anna Köttgen;Cristian Pattaro;Carsten A. Böger;Christian Fuchsberger

  • Autosomal dominant immune dysregulation syndrome in humans with CTLA4 mutations.

    Desireé Schubert;Desireé Schubert;Claudia Bode;Rupert Kenefeck;Tie Zheng Hou

  • The adaptor ASC has extracellular and 'prionoid' activities that propagate inflammation

    Bernardo S Franklin;Lukas Bossaller;Dominic De Nardo;Jacqueline M Ratter

  • Mutations in the gene encoding the 3'-5' DNA exonuclease TREX1 are associated with systemic lupus erythematosus.

    Min Ae Lee-Kirsch;Maolian Gong;Dipanjan Chowdhury;Lydia Senenko

  • Impaired glucose tolerance, beta cell function and lipid metabolism in HIV patients under treatment with protease inhibitors.

    Georg Behrens;Andre Dejam;Hartmut Schmidt;Hans-Joachim Balks

  • Clinical picture and treatment of 2212 patients with common variable immunodeficiency

    Benjamin Gathmann;Nizar Mahlaoui;Laurence Gérard;Eric Oksenhendler

  • The IgG Fc receptor family

    J. E. Gessner;H. Heiken;A. Tamm;R. E. Schmidt

  • CD56bright cells differ in their KIR repertoire and cytotoxic features from CD56dim NK cells.

    Roland Jacobs;Gabriele Hintzen;Almut Kemper;Katrin Beul

  • Surfactant alterations in severe pneumonia, acute respiratory distress syndrome, and cardiogenic lung edema.

    A Günther;C Siebert;R Schmidt;S Ziegler

  • Impaired IgG-Dependent Anaphylaxis and Arthus Reaction in FcγRIII (CD16) Deficient Mice

    Wouter L.W Hazenbos;J.Engelbert Gessner;Frans M.A Hofhuis;Henri Kuipers

  • Infection with GB virus C and reduced mortality among HIV-infected patients.

    Hans L. Tillmann;Hans Heiken;Adriana Knapik-Botor;Stefan Heringlake

  • Generation of monoclonal antibodies to a human natural killer clone. Characterization of two natural killer-associated antigens, NKH1A and NKH2, expressed on subsets of large granular lymphocytes.

    T Hercend;J D Griffin;A Bensussan;R E Schmidt

  • Vascular complications associated with use of HIV protease inhibitors.

    Georg Behrens;Hartmut Schmidt;Dirk Meyer;Matthias Stoll

  • Activation of cytolytic T lymphocyte and natural killer cell function through the T11 sheep erythrocyte binding protein.

    Robert F. Siliciano;Joanne C. Pratt;Reinhold E. Schmidt;Jerome Ritz

  • Meta-analysis identifies multiple loci associated with kidney function–related traits in east Asian populations

    Y. Okada;X. Sim;X. Sim;M. J. Go;J. Y. Wu;J. Y. Wu

  • Catecholamines modulate human NK cell circulation and function via spleen-independent beta 2-adrenergic mechanisms.

    M Schedlowski;W Hosch;R Oberbeck;R J Benschop

  • Hepatitis B and C in HIV-infected patients: Prevalence and prognostic value

    Johann Ockenga;Hans Ludger Tillmann;Christian Trautwein;Matthias Stoll

  • C5a anaphylatoxin is a major regulator of activating versus inhibitory FcγRs in immune complex–induced lung disease

    Nelli Shushakova;Julia Skokowa;Jurriaan Schulman;Ulrich Baumann

  • Changes of natural killer cells during acute psychological stress.

    Manfred Schedlowski;Roland Jacobs;Gertrud Stratmann;Stefan Richter

  • Genetic risk factors for ischaemic stroke and its subtypes (the METASTROKE Collaboration): a meta-analysis of genome-wide association studies | NOVA. The University of Newcastle's Digital Repository

    Matthew Traylor;Martin Farrall;Unnur Thorsteinsdottir;Mike A. Nalls

Frequent Co-Authors

Torsten Witte
Torsten Witte Hannover Medical School
Vilmundur Gudnason
Vilmundur Gudnason University of Iceland
Lenore J. Launer
Lenore J. Launer National Institutes of Health
Albert V. Smith
Albert V. Smith University of Michigan–Ann Arbor
Tamara B. Harris
Tamara B. Harris National Institutes of Health
André G. Uitterlinden
André G. Uitterlinden Erasmus University Rotterdam
Bruce M. Psaty
Bruce M. Psaty University of Washington
Sudha Seshadri
Sudha Seshadri The University of Texas Health Science Center at San Antonio
M. Arfan Ikram
M. Arfan Ikram Erasmus University Rotterdam
Albert Hofman
Albert Hofman Harvard University

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