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Taroh Kinoshita

Taroh Kinoshita

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Genetics and Molecular Biology
Japan
2024

D-Index & Metrics

Molecular Biology

D-Index
111
Citations
40913
World Ranking
362
National Ranking
26

Research.com Recognitions

  • 2024 - Research.com Genetics and Molecular Biology in Japan Leader Award

Overview

Taroh Kinoshita is affiliated with Osaka University in Japan and has an extensive research portfolio primarily in the fields of Biochemistry, Genetics and Molecular Biology, and Medicine. Their scholarly work spans over 70 publications in these main fields, including significant contributions to the subfields of Molecular Biology, Epidemiology, Cell Biology, Physiology, and Genetics.

The primary focus areas of Kinoshita's research include Trypanosoma species research and implications, Cellular transport and secretion, and Lysosomal Storage Disorders Research. Additional research interests encompass Endoplasmic Reticulum Stress and Disease, the Complement system in diseases, CRISPR and Genetic Engineering, and Biochemical and Molecular Research.

Kinoshita has contributed multiple articles to frequent publication venues such as the Journal of Biological Chemistry, bioRxiv (Cold Spring Harbor Laboratory), Blood, Nature Communications, and Glycobiology. This distribution highlights a consistent presence in journals that cover biochemistry, molecular biology, and medical science.

The scientist's recent notable papers include:

  • Biosynthesis and biology of mammalian GPI-anchored proteins, 2020, Open Biology
  • Cross-talks of glycosylphosphatidylinositol biosynthesis with glycosphingolipid biosynthesis and ER-associated degradation, 2020, Nature Communications
  • A knockout cell library of GPI biosynthetic genes for functional studies of GPI-anchored proteins, 2021, Communications Biology
  • Bi-allelic Variants in the GPI Transamidase Subunit PIGK Cause a Neurodevelopmental Syndrome with Hypotonia, Cerebellar Atrophy, and Epilepsy, 2020, The American Journal of Human Genetics
  • Genome-wide CRISPR screen reveals CLPTM1L as a lipid scramblase required for efficient glycosylphosphatidylinositol biosynthesis, 2022, Proceedings of the National Academy of Sciences

Collaboration is a significant aspect of Kinoshita's research, with frequent co-authors including Yoshiko Murakami, Morihisa Fujita, Yi-Shi Liu, Xiao-Dong Gao, and Yicheng Wang. These collaborations indicate ongoing partnerships across multiple projects and disciplines within molecular and cellular biology.

Best Publications

  • Essentials of Glycobiology [Internet]

    Ajit Varki;Richard D Cummings;Jeffrey D Esko;Pamela Stanley

  • Deficiency of the GPI anchor caused by a somatic mutation of the PIG-A gene in paroxysmal nocturnal hemoglobinuria.

    Junji Takeda;Toshio Miyata;Kazuyoshi Kawagoe;Yoshiyasu Iida;Yoshiyasu Iida

  • Symbol Nomenclature for Graphical Representations of Glycans.

    Ajit Varki;Richard D. Cummings;Markus Aebi;Nicole H. Packer

  • Diagnosis and management of paroxysmal nocturnal hemoglobinuria.

    Charles Parker;Mitsuhiro Omine;Stephen Richards;Jun-Ichi Nishimura

  • Direct recognition of the mycobacterial glycolipid, trehalose dimycolate, by C-type lectin Mincle

    Eri Taniguchi Ishikawa;Tetsuaki Ishikawa;Tetsuaki Ishikawa;Yasu S Morita;Kenji Toyonaga

  • Inhibition of complement activation on the surface of cells after incorporation of decay-accelerating factor (DAF) into their membranes.

    M E Medof;T Kinoshita;Nussenzweig

  • The Cloning of PIG-A, a Component in the Early Step of GPI-Anchor Biosynthesis

    Toshio Miyata;Junji Takeda;Yoshiyasu Iida;Norio Yamada

  • β2-Microglobulin modified with advanced glycation end products is a major component of hemodialysis-associated amyloidosis

    Toshio Miyata;Osamu Oda;Reiko Inagi;Yoshiyasu Iida

  • Distribution of decay-accelerating factor in the peripheral blood of normal individuals and patients with paroxysmal nocturnal hemoglobinuria.

    T Kinoshita;M E Medof;R Silber;V Nussenzweig

  • Paroxysmal nocturnal haemoglobinuria (PNH) is caused by somatic mutations in the PIG-A gene.

    M Bessler;P J Mason;P Hillmen;T Miyata

  • Genetic Variants in C5 and Poor Response to Eculizumab

    Jun-ichi Nishimura;Masaki Yamamoto;Shin Hayashi;Kazuma Ohyashiki

  • Inherited complete deficiency of 20-kilodalton homologous restriction factor (CD59) as a cause of paroxysmal nocturnal hemoglobinuria.

    M Yamashina;E Ueda;T Kinoshita;T Takami

  • Paroxysmal nocturnal haemoglobinuria

    Anita Hill;Amy E. DeZern;Taroh Kinoshita;Robert A. Brodsky

  • Identity-by-descent filtering of exome sequence data identifies PIGV mutations in hyperphosphatasia mental retardation syndrome

    Peter M Krawitz;Peter M Krawitz;Michal R Schweiger;Michal R Schweiger;Christian Rödelsperger;Christian Rödelsperger;Carlo Marcelis

  • A beneficial role of bile pigments as an endogenous tissue protector: anti-complement effects of biliverdin and conjugated bilirubin.

    Tatsuyoshi Nakagami;Koji Toyomura;Taroh Kinoshita;Seiji Morisawa

  • Clinical course and flow cytometric analysis of paroxysmal nocturnal hemoglobinuria in the United States and Japan.

    Jun-Ichi Nishimura;Yuzuru Kanakura;Russell E. Ware;Tsutomu Shichishima

  • Defective stratum corneum and early neonatal death in mice lacking the gene for transglutaminase 1 (keratinocyte transglutaminase)

    Masato Matsuki;Fumiyoshi Yamashita;Akemi Ishida-Yamamoto;Keiko Yamada

  • Biosynthesis, remodelling and functions of mammalian GPI-anchored proteins: recent progress.

    Taroh Kinoshita;Morihisa Fujita;Yusuke Maeda

  • Tissue-specific knockout of the mouse Pig-a gene reveals important roles for GPI-anchored proteins in skin development

    Masahito Tarutani;Satoshi Itami;Masaru Okabe;Masahito Ikawa

  • Abnormalities of PIG-A Transcripts in Granulocytes from Patients with Paroxysmal Nocturnal Hemoglobinuria

    Toshio Miyata;Norio Yamada;Yoshiyasu Iida;Junichi Nishimura

Frequent Co-Authors

Junji Takeda
Junji Takeda Osaka University
Yuzuru Kanakura
Yuzuru Kanakura Osaka University
Stefan Mundlos
Stefan Mundlos Max Planck Society
Peter N. Robinson
Peter N. Robinson The Jackson Laboratory
Masaru Okabe
Masaru Okabe Osaka University
Kazuma Ohyashiki
Kazuma Ohyashiki Tokyo Medical University
Ryo Taguchi
Ryo Taguchi University of Tokyo
Toshio Miyata
Toshio Miyata Tohoku University
Tsukasa Seya
Tsukasa Seya Hokkaido University
Howard Riezman
Howard Riezman University of Geneva

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