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Kazuma Ohyashiki

Kazuma Ohyashiki

D-Index & Metrics

Biology and Biochemistry

D-Index
66
Citations
24962
World Ranking
8462
National Ranking
568

Overview

Kazuma Ohyashiki is affiliated with Tokyo Medical University in Japan. Their research primarily focuses on the field of medicine, with a significant emphasis on hematology and genetics. The scientist has contributed extensively to molecular biology as well as pathology and forensic medicine.

The main topics of their work include:

  • Acute Myeloid Leukemia Research
  • Myeloproliferative Neoplasms: Diagnosis and Treatment
  • Chronic Myeloid Leukemia Treatments
  • Lymphoma Diagnosis and Treatment
  • Sarcoma Diagnosis and Treatment
  • MicroRNA in disease regulation
  • Histone Deacetylase Inhibitors Research

Kazuma Ohyashiki has published in a number of scientific journals, frequently contributing to the following venues:

  • Blood
  • Oncology Letters
  • NEJM Evidence
  • Nature Communications
  • Blood Cancer Discovery

Their recent papers include:

  • Molecular International Prognostic Scoring System for Myelodysplastic Syndromes, 2022, NEJM Evidence
  • Germ lineDDX41mutations define a unique subtype of myeloid neoplasms, 2022, Blood
  • Clonal evolution and clinical implications of genetic abnormalities in blastic transformation of chronic myeloid leukaemia, 2021, Nature Communications
  • Amplified EPOR / JAK2 Genes Define a Unique Subtype of Acute Erythroid Leukemia, 2022, Blood Cancer Discovery
  • Postazacitidine clone size predicts long-term outcome of patients with myelodysplastic syndromes and related myeloid neoplasms, 2023, Blood Advances

The scientist collaborates regularly with several coauthors, including:

  • Seishi Ogawa
  • Yasuhito Nannya
  • Yasushi Miyazaki
  • June Takeda
  • Kenichi Yoshida

Best Publications

  • International Scoring System for Evaluating Prognosis in Myelodysplastic Syndromes

    Peter Greenberg;Christopher Cox;Michelle M. LeBeau;Pierre Fenaux

  • Exosomal miR-135b shed from hypoxic multiple myeloma cells enhances angiogenesis by targeting factor-inhibiting HIF-1

    Tomohiro Umezu;Hiroko Tadokoro;Kenko Azuma;Seiichiro Yoshizawa

  • The t(7;11)(p15;p15) translocation in acute myeloid leukaemia fuses the genes for nucleoporin NUP98 and class I homeoprotein HOXA9.

    Julian Borrow;Amanda M. Shearman;Vincent P. Stanton;Reinhard Becher

  • Fusion of the nucleoporin gene NUP98 to HOXA9 by the chromosome translocation t(7;11)(p15;p15) in human myeloid leukaemia

    Takuro Nakamura;David A. Largaespada;Maxwell P. Lee;Laura A. Johnson

  • New Comprehensive Cytogenetic Scoring System for Primary Myelodysplastic Syndromes (MDS) and Oligoblastic Acute Myeloid Leukemia After MDS Derived From an International Database Merge

    Julie Schanz;Heinz Tüchler;Francesc Solé;Mar Mallo

  • Leukemia cell to endothelial cell communication via exosomal miRNAs.

    T Umezu;K Ohyashiki;M Kuroda;J H Ohyashiki

  • Exosomes Derived from Hypoxic Leukemia Cells Enhance Tube Formation in Endothelial Cells

    Hiroko Tadokoro;Hiroko Tadokoro;Tomohiro Umezu;Kazuma Ohyashiki;Toshihiko Hirano

  • Genetic Variants in C5 and Poor Response to Eculizumab

    Jun-ichi Nishimura;Masaki Yamamoto;Shin Hayashi;Kazuma Ohyashiki

  • Telomeric length and telomerase activity vary with age in peripheral blood cells obtained from normal individuals

    Hiroshi Iwama;Kazuma Ohyashiki;Junko H. Ohyashiki;Shigifumi Hayashi

  • Down-Regulation of miR-92 in Human Plasma Is a Novel Marker for Acute Leukemia Patients

    Masami Tanaka;Kosuke Oikawa;Masakatsu Takanashi;Motoshige Kudo

  • Hlf, a novel hepatic bZIP protein, shows altered DNA-binding properties following fusion to E2A in t(17;19) acute lymphoblastic leukemia.

    Stephen P. Hunger;Kazuma Ohyashiki;Keisuke Toyama;Michael L. Cleary

  • Tumor-related leukocytosis is linked with poor prognosis in patients with lung carcinoma.

    Ikuma Kasuga M.D.;Shigeru Makino;Hiroshi Kiyokawa M.D.;Harubumi Katoh M.D.

  • Telomerase inhibition with a novel G-quadruplex-interactive agent, telomestatin: in vitro and in vivo studies in acute leukemia

    T Tauchi;K Shin-ya;G Sashida;M Sumi

  • Activity of a novel G-quadruplex-interactive telomerase inhibitor, telomestatin (SOT-095), against human leukemia cells: involvement of ATM-dependent DNA damage response pathways.

    Tetsuzo Tauchi;Kazuo Shin-Ya;Goro Sashida;Masahiko Sumi

  • The Wilms' tumor gene WT1 is a good marker for diagnosis of disease progression of myelodysplastic syndromes.

    H. Tamaki;H. Ogawa;K. Ohyashiki;Jh H. Ohyashiki

  • Clinical implications of chromosomal abnormalities in 401 patients with myelodysplastic syndromes: a multicentric study in Japan.

    Toyama K;Ohyashiki K;Yoshida Y;Abe T

  • Telomeres and telomerase in hematologic neoplasia

    Junko H Ohyashiki;Junko H Ohyashiki;Goro Sashida;Tetsuzo Tauchi;Kazuma Ohyashiki

  • Discontinuation of imatinib in Japanese patients with chronic myeloid leukemia

    Naoto Takahashi;Taiichi Kyo;Yasuhiro Maeda;Takashi Sugihara

  • Telomere Shortening Associated with Disease Evolution Patterns in Myelodysplastic Syndromes

    Junko H. Ohyashiki;Kazuma Ohyashiki;Toshikatsu Fujimura;Ken Kawakubo

  • Enhancement of intracellular signaling associated with hematopoietic progenitor cell survival in response to SDF-1/CXCL12 in synergy with other cytokines.

    Younghee Lee;Akihiko Gotoh;Akihiko Gotoh;Hyung-Joo Kwon;Hyung-Joo Kwon;Minute You;Minute You

Frequent Co-Authors

Seishi Ogawa
Seishi Ogawa Kyoto University
Tomoki Naoe
Tomoki Naoe Nagoya University
Shinji Nakao
Shinji Nakao Kanazawa University
Shigeru Chiba
Shigeru Chiba University of Tsukuba
John M. Bennett
John M. Bennett University of Rochester Medical Center
Peter L. Greenberg
Peter L. Greenberg Stanford University
Keiya Ozawa
Keiya Ozawa Jichi Medical University
Ulrich Germing
Ulrich Germing Heinrich Heine University Düsseldorf
Yuzuru Kanakura
Yuzuru Kanakura Osaka University
Francesc Solé
Francesc Solé Autonomous University of Barcelona

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