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Masaru Okabe

Masaru Okabe

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Biology and Biochemistry
Japan
2026

D-Index & Metrics

Biology and Biochemistry

D-Index
114
Citations
45394
World Ranking
839
National Ranking
40

Medicine

D-Index
113
Citations
45105
World Ranking
4972
National Ranking
104

Research.com Recognitions

  • 2026 - Research.com Biology and Biochemistry in Japan Leader Award
  • 2025 - Research.com Biology and Biochemistry in Japan Leader Award
  • 2023 - Research.com Biology and Biochemistry in Japan Leader Award

Overview

Masaru Okabe is affiliated with Osaka University in Japan and has contributed extensively to the field of medicine, particularly focusing on reproductive medicine and related biomedical areas.

Their research spans several subfields including reproductive medicine, public health, environmental and occupational health, surgery, pulmonary and respiratory medicine, and molecular biology. The primary topics covered in their work include reproductive biology and fertility, sperm and testicular function, gallbladder and bile duct disorders, cholangiocarcinoma and gallbladder cancer studies, lipid metabolism and biosynthesis, phytochemicals and antioxidant activities, and natural antidiabetic agents studies.

Okabe's publications have appeared frequently in venues such as Human Reproduction, HPB, Science, Journal of Food and Drug Analysis, and The FASEB Journal. Notable recent papers from 2020 include:

  • "NELL2-mediated lumicrine signaling through OVCH2 is required for male fertility," Science, 2020
  • "Comparison of anti-hyperglycemic activities between low- and high-degree of polymerization procyanidin fractions from cacao liquor extract," Journal of Food and Drug Analysis, 2020
  • "Genetic loss of importin α4 causes abnormal sperm morphology and impacts on male fertility in mouse," The FASEB Journal, 2020
  • "Reduction in BDNF from Inefficient Precursor Conversion Influences Nest Building and Promotes Depressive-Like Behavior in Mice," International Journal of Molecular Sciences, 2020
  • "Haprin-deficient spermatozoa are incapable of in vitro fertilization," Molecular Reproduction and Development, 2020

The frequent coauthors collaborating with Okabe include Masahito Ikawa, Jun Muto, Hiroki Kitagawa, K. Kawamoto, and Kentaro Takahashi. Each of these collaborators has appeared in multiple joint publications, indicating ongoing research partnerships.

Best Publications

  • Role of adaptor TRIF in the MyD88-independent toll-like receptor signaling pathway.

    Masahiro Yamamoto;Shintaro Sato;Hiroaki Hemmi;Katsuaki Hoshino

  • Green mice' as a source of ubiquitous green cells

    Masaru Okabe;Masahito Ikawa;Katsuya Kominami;Tomoko Nakanishi

  • DNA methylation of retrotransposon genes is regulated by Piwi family members MILI and MIWI2 in murine fetal testes

    Satomi Kuramochi-Miyagawa;Toshiaki Watanabe;Kengo Gotoh;Yasushi Totoki

  • The immunoglobulin superfamily protein Izumo is required for sperm to fuse with eggs

    Naokazu Inoue;Masahito Ikawa;Ayako Isotani;Masaru Okabe

  • Mili, a mammalian member of piwi family gene, is essential for spermatogenesis.

    Satomi Kuramochi-Miyagawa;Tohru Kimura;Takashi W. Ijiri;Taku Isobe

  • Requirement of CD9 on the egg plasma membrane for fertilization.

    Kenji Miyado;Gen Yamada;Shuichi Yamada;Hidetoshi Hasuwa

  • Innate versus learned odour processing in the mouse olfactory bulb

    Ko Kobayakawa;Reiko Kobayakawa;Hideyuki Matsumoto;Yuichiro Oka

  • PGC7/Stella protects against DNA demethylation in early embryogenesis.

    Toshinobu Nakamura;Yoshikazu Arai;Hiroki Umehara;Masaaki Masuhara

  • Cis3/Socs3/Ssi3 Plays a Negative Regulatory Role in Stat3 Activation and Intestinal Inflammation

    Asuka Suzuki;Toshikatsu Hanada;Keiichi Mitsuyama;Takafumi Yoshida

  • Generating green fluorescent mice by germline transmission of green fluorescent ES cells

    Anna Katerina Hadjantonakis;Marina Gertsenstein;Masahito Ikawa;Masaru Okabe

  • Dysregulation of TGF-β1 receptor activation leads to abnormal lung development and emphysema-like phenotype in core fucose-deficient mice

    Xiangchun Wang;Shinya Inoue;Jianguo Gu;Eiji Miyoshi

  • Most fertilizing mouse spermatozoa begin their acrosome reaction before contact with the zona pellucida during in vitro fertilization

    Mayuko Jin;Eiji Fujiwara;Yasutaka Kakiuchi;Masaru Okabe

  • Bone Marrow Is a Reservoir of Repopulating Mesangial Cells during Glomerular Remodeling

    Takahito Ito;Akira Suzuki;Enyu Imai;Masaru Okabe

  • Activation of Akt signaling is sufficient to maintain pluripotency in mouse and primate embryonic stem cells.

    S Watanabe;H Umehara;K Murayama;M Okabe

  • Pravastatin induces placental growth factor (PGF) and ameliorates preeclampsia in a mouse model

    Keiichi Kumasawa;Masahito Ikawa;Hiroyasu Kidoya;Hidetoshi Hasuwa

  • A histone H3 lysine 36 trimethyltransferase links Nkx2-5 to Wolf–Hirschhorn syndrome

    Keisuke Nimura;Kiyoe Ura;Hidetaka Shiratori;Masato Ikawa

  • Suppression of STAT5 functions in liver, mammary glands, and T cells in cytokine-inducible SH2-containing protein 1 transgenic mice.

    Akira Matsumoto;Youichi Seki;Masato Kubo;Satoshi Ohtsuka

  • Nestin-EGFP transgenic mice: visualization of the self-renewal and multipotency of CNS stem cells.

    Ayano Kawaguchi;Takaki Miyata;Takaki Miyata;Kazunobu Sawamoto;Noriko Takashita

  • Signal transducer and activator of transcription 3 in the heart transduces not only a hypertrophic signal but a protective signal against doxorubicin-induced cardiomyopathy.

    Keita Kunisada;Shinji Negoro;Eiroh Tone;Masanobu Funamoto

  • Fertilization: a sperm’s journey to and interaction with the oocyte

    Masahito Ikawa;Naokazu Inoue;Adam M. Benham;Masaru Okabe

Frequent Co-Authors

Masahito Ikawa
Masahito Ikawa Osaka University
Yoshitake Nishimune
Yoshitake Nishimune Osaka University
Tsukasa Seya
Tsukasa Seya Hokkaido University
Taroh Kinoshita
Taroh Kinoshita Osaka University
Junji Takeda
Junji Takeda Osaka University
Misako Matsumoto
Misako Matsumoto Aomori University
Toru Nakano
Toru Nakano Osaka University
Tadashi Baba
Tadashi Baba University of Tsukuba
Kiyotaka Toshimori
Kiyotaka Toshimori Chiba University
Tadanori Mayumi
Tadanori Mayumi Kobe Gakuin University

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