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Kiyoshi Takeda

Kiyoshi Takeda

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Immunology
Japan
2026
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Medicine
Japan
2023

D-Index & Metrics

Immunology

D-Index
159
Citations
174306
World Ranking
82
National Ranking
7

Medicine

D-Index
160
Citations
175199
World Ranking
760
National Ranking
13

Research.com Recognitions

  • 2026 - Research.com Immunology in Japan Leader Award
  • 2025 - Research.com Immunology in Japan Leader Award
  • 2023 - Research.com Immunology in Japan Leader Award
  • 2023 - Research.com Medicine in Japan Leader Award
  • 2022 - Research.com Immunology in Japan Leader Award

Overview

Kiyoshi Takeda is affiliated with Osaka University in Japan and has a substantial body of research focused on microbial interactions and immune system functions. Their work spans several interconnected areas within biochemistry, genetics, molecular biology, and medicine.

The scientist's recent publications reflect a strong focus on the gut microbiota and immune responses. Notable papers include:

  • Interaction Between the Microbiota, Epithelia, and Immune Cells in the Intestine, 2020, Annual Review of Immunology
  • Gut Microbiota-Derived Short-Chain Fatty Acids Promote Prostate Cancer Growth via IGF1 Signaling, 2021, Cancer Research
  • Microbiota-derived butyrate limits the autoimmune response by promoting the differentiation of follicular regulatory T cells, 2020, EBioMedicine
  • Whole gut virome analysis of 476 Japanese revealed a link between phage and autoimmune disease, 2021, Annals of the Rheumatic Diseases
  • Genomic repertoires linked with pathogenic potency of arthritogenic Prevotella copri isolated from the gut of patients with rheumatoid arthritis, 2023, Annals of the Rheumatic Diseases

Takeda collaborates frequently with a group of coauthors, including Hisako Kayama, Daisuke Motooka, Shota Nakamura, Ryu Okumura, and Daisuke Okuzaki, reflecting sustained interdisciplinary efforts in their research network.

Their scholarly output appears regularly in specific publication venues, indicating focused dissemination channels. These include:

  • International Immunology
  • Annals of the Rheumatic Diseases
  • European Journal of Immunology
  • Proceedings of the National Academy of Sciences
  • The Journal of Experimental Medicine

Takeda's work is categorized mainly within the fields of biochemistry, genetics and molecular biology, and medicine. Within these fields, subfields of study include molecular biology, immunology, epidemiology, genetics, and surgery.

The primary research topics they address are:

  • Gut microbiota and health
  • Inflammatory Bowel Disease
  • Clostridium difficile and Clostridium perfringens research
  • Immune Cell Function and Interaction
  • Helicobacter pylori-related gastroenterology studies
  • Liver Disease Diagnosis and Treatment
  • Epigenetics and DNA Methylation

Best Publications

  • Toll-like receptors.

    Kiyoshi Takeda;Tsuneyasu Kaisho;Shizuo Akira

  • Toll-like receptor signalling

    Shizuo Akira;Kiyoshi Takeda

  • A Toll-like receptor recognizes bacterial DNA.

    Hiroaki Hemmi;Osamu Takeuchi;Taro Kawai;Tsuneyasu Kaisho

  • Erratum A Toll-like receptor recognizes bacterial DNA

    Hiroaki Hemmi;Osamu Takeuchi;Taro Kawai;Tsuneyasu Kaisho

  • Toll-like receptors: critical proteins linking innate and acquired immunity.

    Shizuo Akira;Kiyoshi Takeda;Tsuneyasu Kaisho

  • Toll-like receptors in innate immunity.

    Kiyoshi Takeda;Shizuo Akira

  • Induction of Intestinal Th17 Cells by Segmented Filamentous Bacteria

    Ivaylo I. Ivanov;Koji Atarashi;Nicolas Manel;Eoin L. Brodie

  • Cutting edge: Toll-like receptor 4 (TLR4)-deficient mice are hyporesponsive to lipopolysaccharide: evidence for TLR4 as the Lps gene product.

    Katsuaki Hoshino;Osamu Takeuchi;Taro Kawai;Hideki Sanjo

  • Differential roles of TLR2 and TLR4 in recognition of gram-negative and gram-positive bacterial cell wall components.

    Osamu Takeuchi;Katsuaki Hoshino;Taro Kawai;Hideki Sanjo

  • Induction of Colonic Regulatory T Cells by Indigenous Clostridium Species

    Koji Atarashi;Takeshi Tanoue;Tatsuichiro Shima;Akemi Imaoka

  • Role of adaptor TRIF in the MyD88-independent toll-like receptor signaling pathway.

    Masahiro Yamamoto;Shintaro Sato;Hiroaki Hemmi;Katsuaki Hoshino

  • TLR SIGNALING PATHWAYS

    Kiyoshi Takeda;Shizuo Akira

  • Small anti-viral compounds activate immune cells via the TLR7 MyD88-dependent signaling pathway.

    Hiroaki Hemmi;Tsuneyasu Kaisho;Osamu Takeuchi;Shintaro Sato

  • Targeted Disruption of the MyD88 Gene Results in Loss of IL-1- and IL-18-Mediated Function

    Osamu Adachi;Taro Kawai;Kiyoshi Takeda;Makoto Matsumoto

  • Unresponsiveness of MyD88-Deficient Mice to Endotoxin

    Taro Kawai;Osamu Adachi;Tomohiko Ogawa;Kiyoshi Takeda

  • Essential role of Stat6 in IL-4 signalling

    Kiyoshi Takeda;Takashi Tanaka;Wei Shi;Makoto Matsumoto

  • Targeted disruption of the mouse Stat3 gene leads to early embryonic lethality

    Kiyoshi Takeda;Koichi Noguchi;Wei Shi;Takashi Tanaka

  • Cell type-specific involvement of RIG-I in antiviral response

    Hiroki Kato;Shintaro Sato;Mitsutoshi Yoneyama;Masahiro Yamamoto

  • Toll-like receptors control activation of adaptive immune responses.

    Markus Schnare;Markus Schnare;Gregory M. Barton;Gregory M. Barton;Agnieszka Czopik Holt;Kiyoshi Takeda

  • Cutting Edge: Role of Toll-Like Receptor 1 in Mediating Immune Response to Microbial Lipoproteins

    Osamu Takeuchi;Shintaro Sato;Takao Horiuchi;Katsuaki Hoshino

  • Toll-Like Receptors

    Himanshu Kumar;Kiyoshi Takeda;Shizuo Akira

Frequent Co-Authors

Shizuo Akira
Shizuo Akira Osaka University
Masahiro Yamamoto
Masahiro Yamamoto Osaka University
Osamu Takeuchi
Osamu Takeuchi Kyoto University
Shintaro Sato
Shintaro Sato Osaka University
Katsuaki Hoshino
Katsuaki Hoshino Kagawa University
Tsuneyasu Kaisho
Tsuneyasu Kaisho Wakayama Medical University
Taro Kawai
Taro Kawai Nara Institute of Science and Technology
Satoshi Uematsu
Satoshi Uematsu Osaka Metropolitan University
Atsushi Kumanogoh
Atsushi Kumanogoh Osaka University
Kenji Nakanishi
Kenji Nakanishi Hyogo College of Medicine

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