World's Best Scientists 2026 revealed!
Ken J. Ishii

Ken J. Ishii

D-Index & Metrics

Immunology

D-Index
88
Citations
40302
World Ranking
1142
National Ranking
43

Medicine

D-Index
88
Citations
40306
World Ranking
12940
National Ranking
379

Overview

Ken J. Ishii is a researcher affiliated with the University of Tokyo in Japan, with a primary focus in the field of medicine. Their scholarly output includes more than 200 publications, reflecting extensive work in surgery, pathology and forensic medicine, neurology, orthopedics and sports medicine, and biomedical engineering.

Their research topics cover a variety of spinal and neurological conditions, with significant contributions to areas such as spinal fractures and fixation techniques, spine and intervertebral disc pathology, cervical and thoracic myelopathy, Parkinson's disease and spinal disorders, scoliosis diagnosis and treatment, pelvic and acetabular injuries, and glycogen storage diseases and myoclonus.

Ken J. Ishii has published papers in numerous peer-reviewed journals. Frequent publication venues include:

  • Medicina
  • Scientific Reports
  • Spine Surgery and Related Research
  • Spinal Cord
  • Journal of Clinical Medicine

Recent papers authored by or associated with Ken J. Ishii demonstrate a range of interests within biomedical sciences and clinical applications. Some notable recent publications are:

  • "An antibacterial coated polymer prevents biofilm formation and implant-associated infection" (2021) in Scientific Reports
  • "Computed Tomography-Based Navigation System in Current Spine Surgery: A Narrative Review" (2022) in Medicina
  • "Prognostic Factors for Cervical Spinal Cord Injury without Major Bone Injury in Elderly Patients" (2022) in Journal of Neurotrauma
  • "Clinical outcomes and a therapeutic indication of intramedullary spinal cord astrocytoma" (2021) in Spinal Cord
  • "Bactericidal and Bioresorbable Calcium Phosphate Cements Fabricated by Silver-Containing Tricalcium Phosphate Microspheres" (2020) in International Journal of Molecular Sciences

Throughout their career, Ken J. Ishii has collaborated frequently with several co-authors, including:

  • Haruki Funao
  • Norihiro Isogai
  • Kota Watanabe
  • Yutaka Sasao
  • Morio Matsumoto

The diversity of their research reflects a multidisciplinary approach to spinal and neurological medicine, combining clinical studies, surgical techniques, and material science applications. This breadth is illustrated by topics such as implant-associated infection prevention, spinal surgery navigation, spinal cord injury prognosis, and advanced biomaterials in bone cements.

Best Publications

  • Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses

    Hiroki Kato;Osamu Takeuchi;Shintaro Sato;Mitsutoshi Yoneyama

  • IPS-1, an adaptor triggering RIG-I- and Mda5-mediated type I interferon induction

    Taro Kawai;Ken Takahashi;Ken Takahashi;Shintaro Sato;Cevayir Coban

  • Interferon-α induction through Toll-like receptors involves a direct interaction of IRF7 with MyD88 and TRAF6

    Unknown

  • A Toll-like receptor–independent antiviral response induced by double-stranded B-form DNA

    Ken J Ishii;Cevayir Coban;Hiroki Kato;Ken Takahashi

  • Atg9a controls dsDNA-driven dynamic translocation of STING and the innate immune response

    Tatsuya Saitoh;Naonobu Fujita;Takuya Hayashi;Keigo Takahara

  • Regulation of humoral and cellular gut immunity by lamina propria dendritic cells expressing Toll-like receptor 5

    Satoshi Uematsu;Kosuke Fujimoto;Myoung Ho Jang;Bo Gie Yang

  • Toll-like receptor 9 mediates innate immune activation by the malaria pigment hemozoin

    Cevayir Coban;Ken J. Ishii;Taro Kawai;Hiroaki Hemmi

  • Cutting Edge: Role of Toll-Like Receptor 9 in CpG DNA-Induced Activation of Human Cells

    Fumihiko Takeshita;Cynthia A. Leifer;Ihsan Gursel;Ken J. Ishii

  • TANK-binding kinase-1 delineates innate and adaptive immune responses to DNA vaccines

    Ken J. Ishii;Tatsukata Kawagoe;Shohei Koyama;Kosuke Matsui

  • Human Peripheral Blood Cells Differentially Recognize and Respond to Two Distinct CpG Motifs

    Daniela Verthelyi;Ken J. Ishii;Mayda Gursel;Fumihiko Takeshita

  • The Atg5 Atg12 conjugate associates with innate antiviral immune responses.

    Nao Jounai;Fumihiko Takeshita;Kouji Kobiyama;Asako Sawano

  • Host Innate Immune Receptors and Beyond: Making Sense of Microbial Infections

    Ken J. Ishii;Shohei Koyama;Atsushi Nakagawa;Cevayir Coban

  • Interleukin-1 receptor-associated kinase-1 plays an essential role for Toll-like receptor (TLR)7- and TLR9-mediated interferon-α induction

    Satoshi Uematsu;Shintaro Sato;Masahiro Yamamoto;Tomonori Hirotani

  • Essential role of IPS-1 in innate immune responses against RNA viruses

    Himanshu Kumar;Taro Kawai;Hiroki Kato;Shintaro Sato

  • DNA released from dying host cells mediates aluminum adjuvant activity

    Thomas Marichal;Keiichi Ohata;Denis Bedoret;Claire Mesnil

  • Detection of pathogenic intestinal bacteria by Toll-like receptor 5 on intestinal CD11c+ lamina propria cells.

    Satoshi Uematsu;Myoung Ho Jang;Nicolas Chevrier;Zijin Guo

  • Innate immune response to viral infection.

    Shohei Koyama;Ken J. Ishii;Cevayir Coban;Shizuo Akira

  • Virological characteristics of the SARS-CoV-2 Omicron BA.2 spike

    Unknown

  • Nucleic acid sensing at the interface between innate and adaptive immunity in vaccination.

    Christophe J. Desmet;Ken J. Ishii

  • DNA damage sensor MRE11 recognizes cytosolic double-stranded DNA and induces type I interferon by regulating STING trafficking

    Takeshi Kondo;Junya Kobayashi;Tatsuya Saitoh;Kenta Maruyama

  • Differential role of TLR- and RLR-signaling in the immune responses to influenza A virus infection and vaccination.

    Shohei Koyama;Ken J. Ishii;Himanshu Kumar;Takeshi Tanimoto

Frequent Co-Authors

Shizuo Akira
Shizuo Akira Osaka University
Cevayir Coban
Cevayir Coban University of Tokyo
Dennis M. Klinman
Dennis M. Klinman National Institutes of Health
Masaya Nakamura
Masaya Nakamura Keio University
Satoshi Uematsu
Satoshi Uematsu Osaka Metropolitan University
Masayuki Amagai
Masayuki Amagai Keio University
Toshihiro Horii
Toshihiro Horii Osaka University
Taro Kawai
Taro Kawai Nara Institute of Science and Technology
Shintaro Sato
Shintaro Sato Osaka University
Osamu Takeuchi
Osamu Takeuchi Kyoto University

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

For those interested in Immunology, pursuing related nursing degrees can open diverse career opportunities in healthcare research and patient care. Many students start by exploring the best online BSN programs for non nurses, which are designed to help individuals from varied backgrounds transition into nursing efficiently.

Once you have a nursing foundation, accelerated paths such as the nurse practitioner accelerated program allow you to gain advanced skills quickly, preparing you for specialized roles. Those aiming for higher clinical expertise can consider certifications, including the challenging but rewarding fnp to acute care certification, which equips family nurse practitioners with acute care competencies.

For individuals seeking a more accessible route, the easiest accelerated nursing programs to get into offer a practical starting point, balancing admission criteria with quality education.

Overall, these pathways provide flexibility and specialized knowledge essential for careers intersecting immunology and clinical practice, enabling professionals to contribute to cutting-edge healthcare developments.

Best Scientists Citing Ken J. Ishii

Trending Scientists

Recently Published Articles