D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Microbiology D-index 47 Citations 10,476 107 World Ranking 3656 National Ranking 141

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • DNA
  • Immune system

Hiroyuki Oshiumi mainly investigates Toll-like receptor, Molecular biology, Cell biology, RNA and RIG-I. His Toll-like receptor research incorporates elements of Interferon, Cancer research and Homology. Within one scientific family, Hiroyuki Oshiumi focuses on topics pertaining to TIRAP under Interferon, and may sometimes address concerns connected to Enzyme-linked receptor and Myeloid Differentiation Factor 88.

His Molecular biology study combines topics from a wide range of disciplines, such as Signal transduction, Kinase, Activator and IRF3. He interconnects Homologous recombination, Mre11 complex, DNA repair, Interferon regulatory factors and Nuclease in the investigation of issues within Cell biology. Hiroyuki Oshiumi works mostly in the field of RIG-I, limiting it down to concerns involving Ubiquitin ligase and, occasionally, Type I interferon production, Repressor, Innate immune system and Virology.

His most cited work include:

  • TICAM-1, an adaptor molecule that participates in Toll-like receptor 3-mediated interferon-beta induction. (1065 citations)
  • Subcellular Localization of Toll-Like Receptor 3 in Human Dendritic Cells (649 citations)
  • TIR-containing Adapter Molecule (TICAM)-2, a Bridging Adapter Recruiting to Toll-like Receptor 4 TICAM-1 That Induces Interferon-β (367 citations)

What are the main themes of his work throughout his whole career to date?

Hiroyuki Oshiumi mostly deals with Cell biology, Interferon, Innate immune system, Immunology and Virology. Hiroyuki Oshiumi has included themes like TRIF, Receptor, RNA silencing, TLR3 and MDA5 in his Cell biology study. His Interferon research is multidisciplinary, incorporating elements of Cancer research, Toll-like receptor, RNA, Intrinsic immunity and Molecular biology.

His research investigates the connection between Toll-like receptor and topics such as Gene that intersect with issues in Cell culture. The study incorporates disciplines such as Amino acid, Signal transduction, Signal transducing adaptor protein, Phosphorylation and Peptide sequence in addition to Molecular biology. His work deals with themes such as Microvesicles, Virus and Ubiquitin, Ubiquitin ligase, which intersect with Innate immune system.

He most often published in these fields:

  • Cell biology (52.46%)
  • Interferon (42.62%)
  • Innate immune system (37.70%)

What were the highlights of his more recent work (between 2015-2021)?

  • Cell biology (52.46%)
  • Innate immune system (37.70%)
  • Immunology (31.97%)

In recent papers he was focusing on the following fields of study:

The scientist’s investigation covers issues in Cell biology, Innate immune system, Immunology, Interferon and MDA5. His studies in Cell biology integrate themes in fields like RIG-I, TRIM25, Ubiquitin, Receptor and TLR3. His study in Innate immune system is interdisciplinary in nature, drawing from both Microvesicles, Virus, Dendritic cell and RNA silencing.

Interferon is the subject of his research, which falls under Virology. The various areas that he examines in his MDA5 study include Signal transduction, Gene knockdown and Mitochondrial antiviral-signaling protein. His study connects Molecular biology and RNA.

Between 2015 and 2021, his most popular works were:

  • Combined Blockade of IL6 and PD-1/PD-L1 Signaling Abrogates Mutual Regulation of Their Immunosuppressive Effects in the Tumor Microenvironment. (98 citations)
  • Extracellular Vesicles Including Exosomes Regulate Innate Immune Responses to Hepatitis B Virus Infection. (61 citations)
  • Extracellular Vesicles Deliver Host and Virus RNA and Regulate Innate Immune Response (51 citations)

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

TICAM-1, an adaptor molecule that participates in Toll-like receptor 3-mediated interferon-beta induction.

Hiroyuki Oshiumi;Misako Matsumoto;Kenji Funami;Takashi Akazawa.
Nature Immunology (2003)

1510 Citations

Subcellular Localization of Toll-Like Receptor 3 in Human Dendritic Cells

Misako Matsumoto;Kenji Funami;Masako Tanabe;Hiroyuki Oshiumi.
Journal of Immunology (2003)

961 Citations

TIR-containing Adapter Molecule (TICAM)-2, a Bridging Adapter Recruiting to Toll-like Receptor 4 TICAM-1 That Induces Interferon-β

Hiroyuki Oshiumi;Miwa Sasai;Kyoko Shida;Takashi Fujita.
Journal of Biological Chemistry (2003)

546 Citations

Complex Formation and Functional Versatility of Mre11 of Budding Yeast in Recombination

Takehiko Usui;Tsutomu Ohta;Hiroyuki Oshiumi;Hiroyuki Oshiumi;Jun-ichi Tomizawa.
Cell (1998)

483 Citations

Riplet/RNF135, a RING Finger Protein, Ubiquitinates RIG-I to Promote Interferon-β Induction during the Early Phase of Viral Infection

Hiroyuki Oshiumi;Misako Matsumoto;Shigetsugu Hatakeyama;Tsukasa Seya.
Journal of Biological Chemistry (2009)

368 Citations

Teleost TLR22 recognizes RNA duplex to induce IFN and protect cells from birnaviruses.

Aya Matsuo;Hiroyuki Oshiumi;Tadayuki Tsujita;Hiroshi Mitani.
Journal of Immunology (2008)

367 Citations

Prediction of the prototype of the human Toll-like receptor gene family from the pufferfish, Fugu rubripes, genome

Hiroyuki Oshiumi;Tadayuki Tsujita;Kyoko Shida;Misako Matsumoto.
Immunogenetics (2003)

346 Citations

Toll-like receptor 3: a link between toll-like receptor, interferon and viruses.

Misako Matsumoto;Kenji Funami;Hiroyuki Oshiumi;Tsukasa Seya.
Microbiology and Immunology (2004)

253 Citations

The ubiquitin ligase Riplet is essential for RIG-I-dependent innate immune responses to RNA virus infection.

Hiroyuki Oshiumi;Moeko Miyashita;Naokazu Inoue;Masaru Okabe.
Cell Host & Microbe (2010)

246 Citations

DDX60, a DEXD/H Box Helicase, Is a Novel Antiviral Factor Promoting RIG-I-Like Receptor-Mediated Signaling

Moeko Miyashita;Hiroyuki Oshiumi;Misako Matsumoto;Tsukasa Seya.
Molecular and Cellular Biology (2011)

242 Citations

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