His primary areas of study are Molecular biology, RAD51, Homologous recombination, DNA repair and Cell biology. His Molecular biology research is multidisciplinary, incorporating elements of Transgene, DNA, Transfection, Cell cycle and Fungal protein. Akira Shinohara works mostly in the field of RAD51, limiting it down to topics relating to Replication protein A and, in certain cases, DNA repair protein XRCC4 and DMC1, as a part of the same area of interest.
Akira Shinohara interconnects Genetic recombination and Saccharomyces cerevisiae in the investigation of issues within Homologous recombination. His research investigates the connection between DNA repair and topics such as DNA damage that intersect with problems in Ataxia Telangiectasia Mutated Proteins, Cell cycle checkpoint and DNA supercoil. In Cell biology, Akira Shinohara works on issues like FLP-FRT recombination, which are connected to Site-specific recombination.
Akira Shinohara mainly investigates Cell biology, Homologous recombination, RAD51, Meiosis and Genetics. He has researched Cell biology in several fields, including Histone, Cohesin, DNA damage and Chromosome segregation. His work carried out in the field of Homologous recombination brings together such families of science as Replication protein A and Saccharomyces cerevisiae.
As part of his studies on RAD51, he often connects relevant areas like Molecular biology. His Molecular biology course of study focuses on Ataxia Telangiectasia Mutated Proteins and Ataxia-telangiectasia. His Meiosis study combines topics in areas such as SUN domain, Homologous chromosome and Mutant.
His main research concerns Cell biology, Meiosis, Homologous recombination, DNA damage and Mitosis. His Cell biology study incorporates themes from DNA, Prophase, Cohesin and Chromosome segregation. His Meiosis research is multidisciplinary, relying on both SUN domain, Homologous chromosome, Mutant and Saccharomyces cerevisiae.
His Mutant study also includes fields such as
Akira Shinohara focuses on Cell biology, DNA damage, Meiosis, RAD51 and Homologous recombination. The various areas that Akira Shinohara examines in his Cell biology study include Host protein, Blood proteins and Antigen. His DNA damage study combines topics from a wide range of disciplines, such as Mutant and Meiotic chromosome segregation.
His RAD51 study is concerned with the field of DNA as a whole. The concepts of his Homologous recombination study are interwoven with issues in Saccharomyces cerevisiae, Biophysics, DNA repair, Protein structure and Condensin. His study on Saccharomyces cerevisiae is covered under Genetics.
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Homologous recombination and non‐homologous end‐joining pathways of DNA double‐strand break repair have overlapping roles in the maintenance of chromosomal integrity in vertebrate cells
Minoru Takata;Masao S. Sasaki;Eiichiro Sonoda;Ciaran Morrison.
The EMBO Journal (1998)
Rad51 protein involved in repair and recombination in S. cerevisiae is a RecA-like protein
Akira Shinohara;Hideyuki Ogawa;Tomoko Ogawa.
Rad51‐deficient vertebrate cells accumulate chromosomal breaks prior to cell death
Eiichiro Sonoda;Masao S. Sasaki;Jean Marie Buerstedde;Olga Bezzubova.
The EMBO Journal (1998)
Similarity of the yeast RAD51 filament to the bacterial RecA filament
Tomoko Ogawa;Xiong Yu;Akira Shinohara;Edward H. Egelman.
Cloning of human, mouse and fission yeast recombination genes homologous to RAD51 and recA
Akira Shinohara;Hideyuki Ogawa;Yoichi Matsuda;Noriko Ushio.
Nature Genetics (1993)
Stimulation by Rad52 of yeast Rad51- mediated recombination
Akira Shinohara;Tomoko Ogawa.
The controlling role of ATM in homologous recombinational repair of DNA damage
Ciaran Morrison;Ciaran Morrison;Eiichiro Sonoda;Noriaki Takao;Akira Shinohara.
The EMBO Journal (2000)
Rad52 forms ring structures and co-operates with RPA in single-strand DNA annealing.
Akira Shinohara;Miki Shinohara;Tsutomu Ohta;Shimako Matsuda.
Genes to Cells (1998)
HOMOLOGOUS RECOMBINATION AND THE ROLES OF DOUBLE-STRAND BREAKS
Akira Shinohara;Tomoko Ogawa;Tomoko Ogawa.
Trends in Biochemical Sciences (1995)
Rad52 associates with RPA and functions with rad55 and rad57 to assemble meiotic recombination complexes.
Stephen L. Gasior;Anthony K. Wong;Yoshiteru Kora;Akira Shinohara.
Genes & Development (1998)
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