World's Best Scientists 2026 revealed!
Shunichi Takeda

Shunichi Takeda

Award Badge
Molecular Biology
China
2026
Award Badge
Genetics and Molecular Biology
Japan
2024

D-Index & Metrics

Molecular Biology

D-Index
101
Citations
35445
World Ranking
513
National Ranking
3

Research.com Recognitions

  • 2026 - Research.com Molecular Biology in China Leader Award
  • 2024 - Research.com Genetics and Molecular Biology in Japan Leader Award

Overview

Shunichi Takeda is primarily affiliated with Kyoto University in Japan and has contributed extensively to the fields of Biochemistry, Genetics, and Molecular Biology, with a particular focus on Molecular Biology, Oncology, Cancer Research, Genetics, and Pathology and Forensic Medicine. Their research encompasses over 165 publications across these areas.

The scientist's main research topics focus on DNA Repair Mechanisms, Cancer therapeutics and mechanisms, PARP inhibition in cancer therapy, CRISPR and Genetic Engineering, Carcinogens and Genotoxicity Assessment, Cancer Genomics and Diagnostics, and Polyomavirus and related diseases.

Recent notable papers authored by Shunichi Takeda include:

  • Human topoisomerases and their roles in genome stability and organization, 2022, Nature Reviews Molecular Cell Biology
  • XRCC1 prevents toxic PARP1 trapping during DNA base excision repair, 2021, Molecular Cell
  • A Surge of DNA Damage Links Transcriptional Reprogramming and Hematopoietic Deficit in Fanconi Anemia, 2020, Molecular Cell
  • Fanconi anemia proteins participate in a break-induced-replication-like pathway to counter replication stress, 2021, Nature Structural & Molecular Biology
  • Replication-dependent cytotoxicity and Spartan-mediated repair of trapped PARP1-DNA complexes, 2021, Nucleic Acids Research

Frequent co-authors collaborating with Shunichi Takeda include:

  • Hiroyuki Sasanuma (21 publications)
  • Masataka Tsuda (15 publications)
  • Kouji Hirota (14 publications)
  • Jun Nakamura (11 publications)
  • Yves Pommier (10 publications)

The scientist's work has been published across a variety of journals and venues, with the most frequent publication venues being:

  • UNC Libraries (11 publications)
  • Nucleic Acids Research (5 publications)
  • bioRxiv (Cold Spring Harbor Laboratory) (5 publications)
  • PLoS ONE (4 publications)
  • Cell Reports (3 publications)

Best Publications

  • Trapping of PARP1 and PARP2 by Clinical PARP Inhibitors

    Junko Murai;Shar Yin N. Huang;Benu Brata Das;Amelie Renaud

  • Homologous recombination and non‐homologous end‐joining pathways of DNA double‐strand break repair have overlapping roles in the maintenance of chromosomal integrity in vertebrate cells

    Minoru Takata;Masao S. Sasaki;Eiichiro Sonoda;Ciaran Morrison

  • Rad51‐deficient vertebrate cells accumulate chromosomal breaks prior to cell death

    Eiichiro Sonoda;Masao S. Sasaki;Jean Marie Buerstedde;Olga Bezzubova

  • Increased ratio of targeted to random integration after transfection of chicken B cell lines.

    Jean Marie Buerstedde;Shunichi Takeda

  • Stereospecific PARP Trapping by BMN 673 and Comparison with Olaparib and Rucaparib

    Junko Murai;Shar-yin N. Huang;Amèlie Renaud;Yiping Zhang

  • Cyclin-dependent kinases and cell-cycle transitions: does one fit all?

    Helfrid Hochegger;Shunichi Takeda;Tim Hunt

  • Differential usage of non-homologous end-joining and homologous recombination in double strand break repair.

    Eiichiro Sonoda;Helfrid Hochegger;Alihossein Saberi;Yoshihito Taniguchi

  • Chromosome Instability and Defective Recombinational Repair in Knockout Mutants of the Five Rad51 Paralogs

    Minoru Takata;Masao S. Sasaki;Seiji Tachiiri;Toru Fukushima

  • Sister chromatid exchanges are mediated by homologous recombination in vertebrate cells.

    Eiichiro Sonoda;Masao S. Sasaki;Ciaran Morrison;Yuko Yamaguchi-Iwai

  • Construction of chimaeric processed immunoglobulin genes containing mouse variable and human constant region sequences

    Shun Ichi Takeda;Takayuki Naito;Kazuaki Hama;Takafumi Noma

  • MHC Class II Molecules Are Not Required for Survival of Newly Generated CD4+ T Cells, but Affect Their Long-Term Life Span

    Shunichi Takeda;Hans Reimer Rodewald;Hiroshi Arakawa;Horst Bluethmann

  • DNA Damage-Dependent Acetylation and Ubiquitination of H2AX Enhances Chromatin Dynamics

    Tsuyoshi Ikura;Satoshi Tashiro;Akemi Kakino;Hiroki Shima

  • Thioredoxin-2 (TRX-2) is an essential gene regulating mitochondria-dependent apoptosis.

    Toru Tanaka;Fumihito Hosoi;Yuko Yamaguchi-Iwai;Hajime Nakamura

  • Reduced X-ray resistance and homologous recombination frequencies in a RAD54-/- mutant of the chicken DT40 cell line.

    Olga Bezzubova;Arkadiy Silbergleit;Yuko Yamaguchi-Iwai;Shunichi Takeda

  • The controlling role of ATM in homologous recombinational repair of DNA damage

    Ciaran Morrison;Ciaran Morrison;Eiichiro Sonoda;Noriaki Takao;Akira Shinohara

  • Nbs1 is essential for DNA repair by homologous recombination in higher vertebrate cells

    Hiroshi Tauchi;Junya Kobayashi;Ken ichi Morishima;Dik C. Van Gent

  • Interleukin 4 as an essential factor for in vitro clonal growth of murine connective tissue-type mast cells.

    Yasushi Hamaguchi;Yasushi Hamaguchi;Yuzuru Kanakura;Jun Fujita;Shun Ichi Takeda

  • Poly(ADP-ribose) polymerase 1 accelerates single-strand break repair in concert with poly(ADP-ribose) glycohydrolase.

    Anna E. O. Fisher;Helfrid Hochegger;Shunichi Takeda;Keith W. Caldecott

  • Scc1/Rad21/Mcd1 Is Required for Sister Chromatid Cohesion and Kinetochore Function in Vertebrate Cells

    Eiichiro Sonoda;Takahiro Matsusaka;Ciaran Morrison;Paola Vagnarelli

  • Mre11 is essential for the maintenance of chromosomal DNA in vertebrate cells

    Yuko Yamaguchi-Iwai;Eiichiro Sonoda;Masao S. Sasaki;Ciaran Morrison

Frequent Co-Authors

Eiichiro Sonoda
Eiichiro Sonoda Kyoto University
Minoru Takata
Minoru Takata Kyoto University
Yves Pommier
Yves Pommier National Institutes of Health
Julian E. Sale
Julian E. Sale MRC Laboratory of Molecular Biology
Ryosuke Takahashi
Ryosuke Takahashi Kyoto University
Kazutoshi Mori
Kazutoshi Mori Kyoto University
James A. Swenberg
James A. Swenberg University of North Carolina at Chapel Hill
Akira Shinohara
Akira Shinohara Osaka University
Tasuku Honjo
Tasuku Honjo Kyoto University

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Exploring Molecular Biology opens doors to a range of healthcare and science careers. Many graduates consider bridging into high-demand fields such as nursing or advanced practice roles. For example, those interested in mental health can research the psychiatric mental health nurse practitioner salary to understand potential earnings across the USA.

If you're thinking about furthering your career quickly, it helps to know how many years to become a nurse practitioner and what educational pathways are available. For registered nurses, the fastest rn to bsn program online options let you earn a bachelor's degree efficiently, so you can move forward without delay.

Looking for a direct transition to advanced roles? Consider the variety of rn to np programs available online that connect associate degree nurses with master's-level qualifications. These programs are designed for flexibility, letting you build on your molecular biology background and open further career opportunities in research, clinical leadership, and beyond.

Best Scientists Citing Shunichi Takeda

Trending Scientists