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Immunology

D-Index
53
Citations
12071
World Ranking
3958
National Ranking
1812

Overview

Xingxing Zang is affiliated with the Albert Einstein College of Medicine in the United States. Their research primarily spans the fields of Medicine and Immunology and Microbiology, with significant contributions in Oncology, Immunology, Molecular Biology, Genetics, and Pulmonary and Respiratory Medicine.

Their work is focused on several key topics including Cancer Immunotherapy and Biomarkers, CAR-T cell therapy research, Immunotherapy and Immune Responses, Immune cells in cancer, Immune Cell Function and Interaction, Glioma Diagnosis and Treatment, and Lymphoma Diagnosis and Treatment.

Xingxing Zang has published extensively, with notable papers including:

  • Molecular Features of Cancer-associated Fibroblast Subtypes and their Implication on Cancer Pathogenesis, Prognosis, and Immunotherapy Resistance (2021) in Clinical Cancer Research
  • KIR3DL3-HHLA2 is a human immunosuppressive pathway and a therapeutic target (2021) in Science Immunology
  • Recent advancements in the B7/CD28 immune checkpoint families: new biology and clinical therapeutic strategies (2023) in Cellular and Molecular Immunology
  • Blockade of the immunosuppressive KIR2DL5/PVR pathway elicits potent human NK cell-mediated antitumor immunity (2022) in Journal of Clinical Investigation
  • Functional Contribution and Clinical Implication of Cancer-Associated Fibroblasts in Glioblastoma (2023) in Clinical Cancer Research

Frequent coauthors in their research include Deyou Zheng, Phillip M. Galbo, Xiaoxin Ren, R. Alejandro Sica, and Christopher Nishimura.

Their work is regularly published in venues such as Blood, Regular and Young Investigator Award Abstracts, Cancer Research, Clinical Cancer Research, and Cancers.

Best Publications

  • BTLA is a lymphocyte inhibitory receptor with similarities to CTLA-4 and PD-1.

    Norihiko Watanabe;Norihiko Watanabe;Maya Gavrieli;John R Sedy;Jianfei Yang;Jianfei Yang

  • Human cancer immunotherapy with antibodies to the PD-1 and PD-L1 pathway

    Kim C. Ohaegbulam;Amer Assal;Eszter Lazar-Molnar;Yu Yao

  • B7x: A widely expressed B7 family member that inhibits T cell activation

    Xingxing Zang;P'ng Loke;Jayon Kim;Kenneth Murphy

  • Molecular Pathways: Targeting B7-H3 (CD276) for Human Cancer Immunotherapy

    Elodie Picarda;Kim C. Ohaegbulam;Xingxing Zang

  • B7-H3 and B7x are highly expressed in human prostate cancer and associated with disease spread and poor outcome

    Xingxing Zang;R. Houston Thompson;Hikmat A. Al-Ahmadie;Hikmat A. Al-Ahmadie;Angel M. Serio

  • The B7 Family and Cancer Therapy: Costimulation and Coinhibition

    Xingxing Zang;James P. Allison

  • Molecular Features of Cancer-associated Fibroblast Subtypes and their Implication on Cancer Pathogenesis, Prognosis, and Immunotherapy Resistance

    Phillip M Galbo;Xingxing Zang;Deyou Zheng

  • Alternative activation is an innate response to injury that requires CD4+ T cells to be sustained during chronic infection

    P'ng Loke;Iain Gallagher;Meera G Nair;Meera G Nair;Xingxing Zang

  • Tumor associated endothelial expression of B7-H3 predicts survival in ovarian carcinomas

    Xingxing Zang;Peggy S Sullivan;Robert A Soslow;Rebecca Waitz

  • Immune infiltration and PD-L1 expression in the tumor microenvironment are prognostic in osteosarcoma.

    Pratistha Koirala;Michael Roth;Jonathan Benjamin Gill;Sajida Piperdi

  • T Cell Immunoglobulin Mucin-3 Crystal Structure Reveals a Galectin-9-Independent Ligand-Binding Surface

    Erhu Cao;Xingxing Zang;Udupi A. Ramagopal;Arunika Mukhopadhaya

  • HHLA2 is a member of the B7 family and inhibits human CD4 and CD8 T-cell function

    Ruihua Zhao;Jordan M. Chinai;Susan Buhl;Lisa Scandiuzzi

  • Cell-cell contact with proinflammatory macrophages enhances the immunotherapeutic effect of mesenchymal stem cells in two abortion models.

    Yanhong Li;Di Zhang;Ling Xu;Lin Dong

  • The contrasting role of B7-H3

    Kimberly A. Hofmeyer;Anjana Ray;Xingxing Zang

  • The third group of the B7-CD28 immune checkpoint family: HHLA2, TMIGD2, B7x, and B7-H3

    Murali Janakiram;Urvi A. Shah;Weifeng Liu;Aimin Zhao

  • New immunotherapies targeting the PD-1 pathway

    Jordan M. Chinai;Murali Janakiram;Fuxiang Chen;Wantao Chen

  • Immune evasion genes from filarial nematodes.

    Rick M. Maizels;Natalia Gomez-Escobar;William F. Gregory;Janice Murray

  • B7-H4(B7x)–Mediated Cross-talk between Glioma-Initiating Cells and Macrophages via the IL6/JAK/STAT3 Pathway Lead to Poor Prognosis in Glioma Patients

    Yu Yao;Hongxing Ye;Zengxin Qi;Lianjie Mo

  • Immune checkpoint blockade and CAR-T cell therapy in hematologic malignancies.

    Hao Wang;Gurbakhash Kaur;Alexander I. Sankin;Fuxiang Chen

  • The PD-1/PD-L1 (B7-H1) pathway in chronic infection-induced cytotoxic T lymphocyte exhaustion

    Kimberly A. Hofmeyer;Hyungjun Jeon;Xingxing Zang

  • A Brugia malayi Homolog of Macrophage Migration Inhibitory Factor Reveals an Important Link Between Macrophages and Eosinophil Recruitment During Nematode Infection

    Franco H. Falcone;P’ng Loke;Xingxing Zang;Andrew S. MacDonald

  • Abstract 4134: Immune infiltration and PD-L1 expression in the tumor microenvironment are prognostic in osteosarcoma

    Pratistha Koirala;Michael Roth;Jonathan Gill;Jordan Chinai

Frequent Co-Authors

James P. Allison
James P. Allison The University of Texas MD Anderson Cancer Center
P'ng Loke
P'ng Loke National Institutes of Health
Rick M. Maizels
Rick M. Maizels University of Glasgow
Joseph A. Sparano
Joseph A. Sparano Albert Einstein College of Medicine
Judith E. Allen
Judith E. Allen University of Manchester
Victor E. Reuter
Victor E. Reuter Memorial Sloan Kettering Cancer Center
Amit Verma
Amit Verma Albert Einstein College of Medicine
Haobo Jiang
Haobo Jiang Oklahoma State University
Ulrich Steidl
Ulrich Steidl Albert Einstein College of Medicine
Michael R. Kanost
Michael R. Kanost Kansas State University

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