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Haidong Dong

Haidong Dong

D-Index & Metrics

Immunology

D-Index
77
Citations
39770
World Ranking
1786
National Ranking
881

Overview

Haidong Dong is affiliated with the Mayo Clinic in the United States and has contributed extensively to medical research, particularly focusing on immunology, oncology, and molecular biology. Their research output spans several subfields including pulmonary and respiratory medicine, as well as surgery.

The primary areas of study for Haidong Dong cover broad topics in medicine and immunology and microbiology. Specific subfields they have contributed to include:

  • Oncology
  • Immunology
  • Molecular Biology
  • Pulmonary and Respiratory Medicine
  • Surgery

The main research topics in their work reflect a strong emphasis on cancer immunotherapy and biomarkers, CAR-T cell therapy, and immune responses. Additional focus areas include:

  • Cancer Immunotherapy and Biomarkers
  • CAR-T cell therapy research
  • Immunotherapy and Immune Responses
  • Immune Cell Function and Interaction
  • Immune cells in cancer
  • Extracellular vesicles in disease
  • Cholangiocarcinoma and Gallbladder Cancer Studies

Haidong Dong's frequent publication venues indicate a consistent presence in immunology and cancer research communities. These venues include:

  • The Journal of Immunology
  • Cancer Research
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Regular and Young Investigator Award Abstracts
  • Journal of Clinical Oncology

Among their recent papers are:

  • "Targeting tumor-associated macrophages and granulocytic myeloid-derived suppressor cells augments PD-1 blockade in cholangiocarcinoma," 2020, Journal of Clinical Investigation
  • "Immune signatures underlying post-acute COVID-19 lung sequelae," 2021, Science Immunology
  • "ICAM-1-mediated adhesion is a prerequisite for exosome-induced T cell suppression," 2022, Developmental Cell
  • "ADAM10 and ADAM17 cleave PD-L1 to mediate PD-(L)1 inhibitor resistance," 2020, OncoImmunology
  • "Regulation of sister chromatid cohesion by nuclear PD-L1," 2020, Cell Research

Frequent collaborators in their research include:

  • Fabrice Lucien
  • Joanina K. Gicobi
  • Henan Zhang
  • Sean S. Park
  • Michelle A. Hsu

Best Publications

  • Tumor-associated B7-H1 promotes T-cell apoptosis: a potential mechanism of immune evasion

    Haidong Dong;Scott E. Strome;Diva R. Salomao;Hideto Tamura

  • B7-H1, a third member of the B7 family, co-stimulates T-cell proliferation and interleukin-10 secretion

    Haidong Dong;Gefeng Zhu;Koji Tamada;Lieping Chen

  • Exosomal PD-L1 Contributes to Immunosuppression and is Associated with anti-PD-1 Response

    Gang Chen;Alexander C. Huang;Wei Zhang;Wei Zhang;Gao Zhang

  • Tumor-associated B7-H1 promotes T-cell apoptosis: A potential mechanism of immune evasion

    Unknown

  • Blockade of B7-H1 improves myeloid dendritic cell-mediated antitumor immunity.

    Tyler J Curiel;Shuang Wei;Haidong Dong;Xavier Alvarez

  • B7-H3: A costimulatory molecule for T cell activation and IFN-γ production

    Andrei I. Chapoval;Jian Ni;Julie S. Lau;Ryan A. Wilcox

  • Blockade of B7-H1 and PD-1 by Monoclonal Antibodies Potentiates Cancer Therapeutic Immunity

    Fumiya Hirano;Katsumi Kaneko;Hideto Tamura;Haidong Dong

  • Costimulatory b7-h1 in renal cell carcinoma patients: indicator of tumor aggressiveness and potential therapeutic target

    Lieping Chen;Scott E. Strome;Eugene D. Kwon

  • Tumor B7-H1 is associated with poor prognosis in renal cell carcinoma patients with long-term follow-up.

    R. Houston Thompson;Susan M. Kuntz;Bradley C. Leibovich;Haidong Dong

  • PD-1 Is Expressed by Tumor-Infiltrating Immune Cells and Is Associated with Poor Outcome for Patients with Renal Cell Carcinoma

    R. Houston Thompson;Haidong Dong;Christine M. Lohse;Bradley C. Leibovich

  • B7-H1 Blockade Augments Adoptive T-Cell Immunotherapy for Squamous Cell Carcinoma

    Scott E. Strome;Haidong Dong;Hideto Tamura;Stephen G. Voss

  • 618: Costimulatory B7-H1 In Renal Cell Carcinoma Patients: Indicator of Tumor Aggressiveness and Potential Therapeutic Target

    R. Houston Thompson;Michael D. Gillett;John C. Cheville;Christine M. Lohse

  • PD-L1 on host cells is essential for PD-L1 blockade–mediated tumor regression

    Haidong Tang;Yong Liang;Robert A. Anders;Janis M. Taube

  • B7-H1 Determines Accumulation and Deletion of Intrahepatic CD8+ T Lymphocytes

    Haidong Dong;Gefeng Zhu;Koji Tamada;Dallas B. Flies

  • B7-H1 pathway and its role in the evasion of tumor immunity

    Haidong Dong;Lieping Chen

  • Pembrolizumab in patients with CLL and Richter transformation or with relapsed CLL

    Wei Ding;Betsy R. LaPlant;Timothy G. Call;Sameer A. Parikh

  • B7-H4 expression in renal cell carcinoma and tumor vasculature: Associations with cancer progression and survival

    Amy E. Krambeck;R. Houston Thompson;Haidong Dong;Christine M. Lohse

  • PD-1 Restrains Radiotherapy-Induced Abscopal Effect

    Sean S. Park;Haidong Dong;Xin Liu;Susan M. Harrington

  • Antibodies Against Immune Checkpoint Molecules Restore Functions of Tumor-Infiltrating T Cells in Hepatocellular Carcinomas

    Guoying Zhou;Dave Sprengers;Patrick P.C. Boor;Michail Doukas

  • Identification of a soluble form of B7-H1 that retains immunosuppressive activity and is associated with aggressive renal cell carcinoma

    Xavier Frigola;Brant A Inman;Christine M Lohse;Christopher J Krco

  • Costimulation of T cells by B7-H2, a B7-like molecule that binds ICOS

    Shengdian Wang;Gefeng Zhu;Andrei I. Chapoval;Haidong Dong

  • Molecular Modeling and Functional Mapping of B7-H1 and B7-DC Uncouple Costimulatory Function from PD-1 Interaction

    Shengdian Wang;Jürgen Bajorath;Jürgen Bajorath;Dallas B. Flies;Haidong Dong

  • B7-H1 costimulation preferentially enhances CD28-independent T-helper cell function

    Hideto Tamura;Haidong Dong;Gefeng Zhu;Gabriel L. Sica

Frequent Co-Authors

Lieping Chen
Lieping Chen Yale University
John C. Cheville
John C. Cheville Mayo Clinic
Koji Tamada
Koji Tamada Yamaguchi University
Michael L. Blute
Michael L. Blute Harvard University
Ying Li
Ying Li Nanjing Agricultural University

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