2022 - Research.com Best Female Scientist Award
2022 - Research.com Best Scientist Award
2020 - Fellow, National Academy of Inventors
2018 - Member of the National Academy of Sciences
2018 - Member of the National Academy of Medicine (NAM)
2017 - Warren Alpert Foundation Prize For their collective contributions to the pre-clinical foundation and development of immune checkpoint blockade, a novel form of cancer therapy that has transformed the landscape of cancer treatment.
2006 - Fellow of the American Association for the Advancement of Science (AAAS)
Arlene H. Sharpe spends much of her time researching Immunology, Cell biology, T cell, Immune system and Cytotoxic T cell. Her Immunology study combines topics in areas such as Cancer research and Cellular differentiation. Her studies deal with areas such as Cell, Immune tolerance, Molecular biology, Programmed Cell Death 1 Ligand 2 Protein and Receptor as well as Cell biology.
Her biological study spans a wide range of topics, including Chronic infection, Haematopoiesis and Transplantation. Her Immune system research incorporates themes from Melanoma and Effector. Her Cytotoxic T cell study frequently draws parallels with other fields, such as CD8.
Her main research concerns Immunology, T cell, Cell biology, Immune system and Cytotoxic T cell. Her research in Antigen, Autoimmunity, CTLA-4, Antibody and Germinal center are components of Immunology. The various areas that Arlene H. Sharpe examines in her T cell study include Molecular biology and Cell.
Arlene H. Sharpe combines subjects such as Receptor, Cellular differentiation and CD40 with her study of Cell biology. Immune system connects with themes related to Inflammation in her study. In Cytotoxic T cell, she works on issues like CD8, which are connected to Cancer research.
Cancer research, CD8, T cell, Cancer and Cytotoxic T cell are her primary areas of study. Arlene H. Sharpe has researched Cancer research in several fields, including Blockade and Immunotherapy, Immune system, Cancer immunotherapy. Her work carried out in the field of CD8 brings together such families of science as Transcriptome and Melanoma.
Her work deals with themes such as Cell, Immune tolerance, Antigen and Cell biology, which intersect with T cell. Her Cytotoxic T cell study integrates concerns from other disciplines, such as Molecular biology and Receptor. Her Autoimmunity research is under the purview of Immunology.
Her primary scientific interests are in Cancer research, Immune system, Immunotherapy, T cell and CD8. The study of Immunology and Internal medicine are components of her Immunotherapy research. Her Immunology study frequently draws connections between adjacent fields such as Insulin resistance.
Her studies in T cell integrate themes in fields like mTORC1, Immune tolerance and Cell biology. Her Cell biology research incorporates elements of Cell, Cellular differentiation, Leucine, Regulatory T cell and Glutamine. Her CD8 study incorporates themes from Cytotoxic T cell, Carcinoma, Progenitor and Cell culture.
This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.
PD-1 and its ligands in tolerance and immunity.
Mary E. Keir;Manish J. Butte;Gordon J. Freeman;Arlene H. Sharpe.
Annual Review of Immunology (2008)
Loss of CTLA-4 leads to massive lymphoproliferation and fatal multiorgan tissue destruction, revealing a critical negative regulatory role of CTLA-4
Elizabeth A. Tivol;Frank Borriello;A.Nicola Schweitzer;William P. Lynch.
Restoring function in exhausted CD8 T cells during chronic viral infection
Daniel L. Barber;E. John Wherry;David Masopust;Baogong Zhu.
PD-L2 is a second ligand for PD-1 and inhibits T cell activation
Yvette Latchman;Clive R. Wood;Tatyana Chernova;Divya Chaudhary.
Nature Immunology (2001)
THE B7 FAMILY REVISITED
Rebecca J. Greenwald;Gordon J. Freeman;Arlene H. Sharpe.
Annual Review of Immunology (2005)
p63 is essential for regenerative proliferation in limb, craniofacial and epithelial development
Annie Yang;Ronen Schweitzer;Deqin Sun;Mourad Kaghad.
B7/CD28 costimulation is essential for the homeostasis of the CD4+CD25+ immunoregulatory T cells that control autoimmune diabetes.
Benoît Salomon;Deborah J Lenschow;Lesley Rhee;Neda Ashourian.
The B7–CD28 superfamily
Arlene H Sharpe;Gordon J Freeman.
Nature Reviews Immunology (2002)
The PD‐1 pathway in tolerance and autoimmunity
Loise M. Francisco;Peter T. Sage;Arlene H. Sharpe;Arlene H. Sharpe.
Immunological Reviews (2010)
Disruption of the Cbfa2 gene causes necrosis and hemorrhaging in the central nervous system and blocks definitive hematopoiesis.
Qing Wang;Terryl Stacy;Michael Binder;Miguel Marin-Padilla.
Proceedings of the National Academy of Sciences of the United States of America (1996)
If you think any of the details on this page are incorrect, let us know.
We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below: