2026 W. Nicholas Haining: Immunology Researcher – H-Index, Publications & Awards

Discipline name	D-Index	World Ranking	Current World Ranking	National Ranking	Current National Ranking	Publications	Citations
Immunology	55	3769	3474	1726	1578	142	28099

Overview

W. Nicholas Haining is affiliated with Arsenal Biosciences in the United States. Their research spans several interdisciplinary fields including Medicine, Immunology and Microbiology, and Biochemistry, Genetics and Molecular Biology. Subfields of study prominently featured in their work include Immunology, Oncology, Molecular Biology, Biomedical Engineering, and Public Health, Environmental and Occupational Health.

The scientist's research primarily focuses on topics related to CAR-T cell therapy, Immune Cell Function and Interaction, CRISPR and Genetic Engineering, T-cell and B-cell Immunology, Immunotherapy and Immune Responses, Cancer Immunotherapy and Biomarkers, as well as Immune cells in cancer.

Recent significant publications by W. Nicholas Haining include:

Epigenetic silencing by SETDB1 suppresses tumour intrinsic immunogenicity, 2021, Nature
Epigenetic scars of CD8+ T cell exhaustion persist after cure of chronic infection in humans, 2021, Nature Immunology
In vivo CRISPR screens reveal the landscape of immune evasion pathways across cancer, 2022, Nature Immunology
The PD-1 Pathway Regulates Development and Function of Memory CD8+ T Cells following Respiratory Viral Infection, 2020, Cell Reports
PI3K activation allows immune evasion by promoting an inhibitory myeloid tumor microenvironment, 2022, Journal for ImmunoTherapy of Cancer

W. Nicholas Haining frequently collaborates with several researchers. Notable co-authors include Kathleen B. Yates, Levi Gray-Rupp, Aaron Cooper, Debattama R. Sen, and Suchismita Mohanty.

The scientist has published extensively in journals such as:

Cancer Research
Regular and Young Investigator Award Abstracts
Nature Immunology
Cancer Immunology Research
bioRxiv (Cold Spring Harbor Laboratory)

Best Publications

Molecular Signature of CD8+ T Cell Exhaustion during Chronic Viral Infection

E. John Wherry;Sang Jun Ha;Susan M. Kaech;W. Nicholas Haining

2492
Citations
Coregulation of CD8+ T cell exhaustion by multiple inhibitory receptors during chronic viral infection

Shawn D Blackburn;Haina Shin;W Nicholas Haining;W Nicholas Haining;Tao Zou

2405
Citations
Subsets of exhausted CD8+ T cells differentially mediate tumor control and respond to checkpoint blockade.

Brian C. Miller;Debattama R. Sen;Debattama R. Sen;Rose Al Abosy;Rose Al Abosy;Kevin Bi;Kevin Bi

1949
Citations
Defining ‘T cell exhaustion’

Christian U Blank;W Nicholas Haining;Werner Held;Patrick G Hogan;Patrick G Hogan

1487
Citations
Epigenetic stability of exhausted T cells limits durability of reinvigoration by PD-1 blockade

Kristen E. Pauken;Morgan A. Sammons;Pamela M. Odorizzi;Sasikanth Manne

1306
Citations
In vivo CRISPR screening identifies Ptpn2 as a cancer immunotherapy target

Robert T. Manguso;Robert T. Manguso;Hans W. Pope;Hans W. Pope;Margaret D. Zimmer;Margaret D. Zimmer;Flavian D. Brown

1152
Citations
Densely Interconnected Transcriptional Circuits Control Cell States in Human Hematopoiesis

Noa Novershtern;Noa Novershtern;Noa Novershtern;Aravind Subramanian;Lee N. Lawton;Raymond H. Mak

1109
Citations
Normalizing the environment recapitulates adult human immune traits in laboratory mice

Lalit K. Beura;Sara E. Hamilton;Kevin Bi;Jason M. Schenkel

1101
Citations
The epigenetic landscape of T cell exhaustion

Debattama R. Sen;James Kaminski;R. Anthony Barnitz;Makoto Kurachi

962
Citations
PD-L1 on tumor cells is sufficient for immune evasion in immunogenic tumors and inhibits CD8 T cell cytotoxicity.

Vikram R. Juneja;Vikram R. Juneja;Vikram R. Juneja;Kathleen A. McGuire;Kathleen A. McGuire;Robert T. Manguso;Martin W. LaFleur;Martin W. LaFleur

918
Citations
Systems biology of vaccination for seasonal influenza in humans

Helder Imoto Nakaya;Jens Wrammert;Eva K Lee;Luigi Racioppi;Luigi Racioppi

905
Citations
Functional and genomic profiling of effector CD8 T cell subsets with distinct memory fates

Surojit Sarkar;Vandana Kalia;W. Nicholas Haining;Bogumila T. Konieczny

797
Citations
CDK4/6 Inhibition Augments Antitumor Immunity by Enhancing T-cell Activation

Jiehui Deng;Jiehui Deng;Eric S. Wang;Russell W. Jenkins;Shuai Li

747
Citations
Prolonged Interleukin-2Rα Expression on Virus-Specific CD8+ T Cells Favors Terminal-Effector Differentiation In Vivo

Vandana Kalia;Surojit Sarkar;Shruti Subramaniam;W. Nicholas Haining

726
Citations
Loss of ADAR1 in tumours overcomes resistance to immune checkpoint blockade.

Jeffrey J. Ishizuka;Jeffrey J. Ishizuka;Robert T. Manguso;Robert T. Manguso;Collins K. Cheruiyot;Collins K. Cheruiyot;Kevin Bi;Kevin Bi

663
Citations
Transcriptional analysis of HIV-specific CD8 + T cells shows that PD-1 inhibits T cell function by upregulating BATF

Michael Quigley;Florencia Pereyra;Björn Nilsson;Filippos Porichis

600
Citations
Origin and differentiation of human memory CD8 T cells after vaccination

Rama Akondy;Mark Fitch;Srilatha Edupuganti;Shu Yang

549
Citations
Stable inhibitory activity of regulatory T cells requires the transcription factor Helios

Hye-Jung Kim;R. Anthony Barnitz;R. Anthony Barnitz;Taras Kreslavsky;Flavian D. Brown

445
Citations
CD39 Expression Identifies Terminally Exhausted CD8+ T Cells

Prakash K. Gupta;Prakash K. Gupta;Jernej Godec;Jernej Godec;David Wolski;Emily Adland

434
Citations
The transcription factor BATF operates as an essential differentiation checkpoint in early effector CD8+ T cells

Makoto Kurachi;R Anthony Barnitz;Nir Yosef;Pamela M Odorizzi

364
Citations
Molecular Signature of CD8+ T Cell Exhaustion during Chronic Viral Infection (DOI:10.1016/j.immuni.2007.09.006)

E. John Wherry;Sang Jun Ha;Susan M. Kaech;W. Nicholas Haining

62
Citations

Frequent Co-Authors

Arlene H. Sharpe Harvard University

E. John Wherry University of Pennsylvania

Benjamin L. Ebert Harvard University

Lee M. Nadler Harvard University

Rafi Ahmed Emory University

Gordon J. Freeman Harvard University

Todd R. Golub Harvard University

Nir Yosef University of California, Berkeley

John G. Doench Broad Institute

Paul Klenerman University of Oxford

External Links

Personal website of W. Nicholas Haining

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