World's Best Scientists 2026 revealed!
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Best Scientists
2025
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Biology and Biochemistry
USA
2023

D-Index & Metrics

Best Scientists

D-Index
186
Citations
292313
World Ranking
477
National Ranking
313

Medicine

D-Index
188
Citations
319723
World Ranking
268
National Ranking
180

Research.com Recognitions

  • 2025 - Research.com Best Scientists Award
  • 2023 - Research.com Biology and Biochemistry in United States Leader Award
  • 2014 - Member of the National Academy of Medicine (NAM)
  • 2008 - E. Mead Johnson Award, Society for Pediatric Research
  • 2007 - Paul Marks Prize for Cancer Research, Memorial Sloan Kettering Cancer Center
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians

Overview

Todd R. Golub is affiliated with Harvard University in the United States and has contributed significantly to the fields of biochemistry, genetics, molecular biology, and medicine. Their research spans various subfields, including molecular biology, cancer research, genetics, oncology, and immunology.

The main topics of their work include:

  • Cancer Genomics and Diagnostics
  • CRISPR and Genetic Engineering
  • Single-cell and spatial transcriptomics
  • RNA modifications and cancer
  • Protein Degradation and Inhibitors
  • Ubiquitin and proteasome pathways
  • Cancer-related molecular mechanisms research

They have published numerous papers in respected scientific venues. Some of the recent publications include:

  • "Copper induces cell death by targeting lipoylated TCA cycle proteins" (2022, Science)
  • "Discovering the anticancer potential of non-oncology drugs by systematic viability profiling" (2020, Nature Cancer)
  • "A metastasis map of human cancer cell lines" (2020, Nature)
  • "The CDK inhibitor CR8 acts as a molecular glue degrader that depletes cyclin K" (2020, Nature)
  • "Fatty acid synthesis is required for breast cancer brain metastasis" (2021, Nature Cancer)

Frequent coauthors in their research include:

  • Francisca Vázquez
  • David E. Root
  • Jennifer A. Roth
  • Jesse S. Boehm
  • William C. Hahn

Their work appears often in notable publication venues, including:

  • Cancer Research
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature
  • Neuro-Oncology
  • Nature Cancer

Todd R. Golub has received several professional recognitions, including:

  • Member of the National Academy of Medicine (NAM), 2014
  • E. Mead Johnson Award, Society for Pediatric Research, 2008
  • Paul Marks Prize for Cancer Research, Memorial Sloan Kettering Cancer Center, 2007
  • Member of the Association of American Physicians

Best Publications

  • Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles

    Aravind Subramanian;Pablo Tamayo;Vamsi K. Mootha;Sayan Mukherjee

  • Molecular classification of cancer: class discovery and class prediction by gene expression monitoring.

    T. R. Golub;T. R. Golub;D. K. Slonim;P. Tamayo;C. Huard

  • MicroRNA expression profiles classify human cancers

    Jun Lu;Gad Getz;Eric A. Miska;Eric A. Miska;Ezequiel Alvarez-Saavedra

  • PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes

    Vamsi K Mootha;Cecilia M Lindgren;Cecilia M Lindgren;Karl-Fredrik Eriksson;Aravind Subramanian

  • Integrated Genomic Analysis Identifies Clinically Relevant Subtypes of Glioblastoma Characterized by Abnormalities in PDGFRA, IDH1, EGFR, and NF1

    Roel G. W. Verhaak;Katherine A. Hoadley;Elizabeth Purdom;Victoria Wang

  • The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity

    Jordi Barretina;Giordano Caponigro;Nicolas Stransky;Kavitha Venkatesan

  • Comprehensive genomic characterization defines human glioblastoma genes and core pathways

    Roger McLendon;Allan Friedman;Darrell Bigner;Erwin G. Van Meir

  • Mutational heterogeneity in cancer and the search for new cancer-associated genes

    Michael S. Lawrence;Petar Stojanov;Petar Stojanov;Paz Polak;Paz Polak;Paz Polak;Gregory V. Kryukov;Gregory V. Kryukov;Gregory V. Kryukov

  • The Connectivity Map: Using Gene-Expression Signatures to Connect Small Molecules, Genes, and Disease

    Justin Lamb;Emily D. Crawford;David Peck;Joshua W. Modell

  • The landscape of somatic copy-number alteration across human cancers

    Rameen Beroukhim;Craig H. Mermel;Craig H. Mermel;Dale Porter;Guo Wei

  • Interpreting patterns of gene expression with self-organizing maps: Methods and application to hematopoietic differentiation

    Pablo Tamayo;Donna Slonim;Jill Mesirov;Qing Zhu

  • Activating mutation in the tyrosine kinase JAK2 in polycythemia vera, essential thrombocythemia, and myeloid metaplasia with myelofibrosis.

    Ross L. Levine;Ross L. Levine;Martha Wadleigh;Jan Cools;Benjamin L. Ebert;Benjamin L. Ebert

  • A Next Generation Connectivity Map: L1000 Platform and the First 1,000,000 Profiles.

    Aravind Subramanian;Rajiv Narayan;Steven M. Corsello;Steven M. Corsello;David D. Peck

  • Discovery and saturation analysis of cancer genes across 21 tumour types

    Michael S. Lawrence;Petar Stojanov;Craig H. Mermel;James T. Robinson

  • Classification of human lung carcinomas by mRNA expression profiling reveals distinct adenocarcinoma subclasses

    Arindam Bhattacharjee;William G. Richards;Jane Staunton;Cheng Li

  • Gene expression correlates of clinical prostate cancer behavior.

    Dinesh Singh;Phillip G. Febbo;Phillip G. Febbo;Kenneth Ross;Donald G. Jackson

  • Diffuse large B-cell lymphoma outcome prediction by gene-expression profiling and supervised machine learning

    Margaret A. Shipp;Ken N. Ross;Pablo Tamayo;Andrew P. Weng

  • A molecular signature of metastasis in primary solid tumors.

    Sridhar Ramaswamy;Ken N. Ross;Eric S. Lander;Todd R. Golub;Todd R. Golub

  • Prediction of central nervous system embryonal tumour outcome based on gene expression

    Scott L. Pomeroy;Pablo Tamayo;Michelle Gaasenbeek;Lisa M. Sturla

  • The Mutational Landscape of Head and Neck Squamous Cell Carcinoma

    N. Stransky;A. M. Egloff;A. D. Tward;A. D. Kostic

Frequent Co-Authors

Eric S. Lander
Eric S. Lander Broad Institute
Gad Getz
Gad Getz Broad Institute
Matthew Meyerson
Matthew Meyerson Harvard University
Benjamin L. Ebert
Benjamin L. Ebert Harvard University
Levi A. Garraway
Levi A. Garraway Roche (United States)
William C. Hahn
William C. Hahn Dana-Farber Cancer Institute
Jesse S. Boehm
Jesse S. Boehm Broad Institute
Michael S. Lawrence
Michael S. Lawrence Harvard University
Francisca Vazquez
Francisca Vazquez Broad Institute
David E. Root
David E. Root Broad Institute

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