World's Best Scientists 2026 revealed!

Overview

Xiang Zhang is a researcher affiliated with the University of Louisville in the United States. Their work spans multiple fields of study, predominantly in Medicine and Biochemistry, Genetics and Molecular Biology.

The scientist's research covers prominent subfields including Molecular Biology, Immunology, Cancer Research, Epidemiology, and Pathology and Forensic Medicine. These areas reflect a broad engagement with both fundamental biological mechanisms and their clinical implications.

Xiang Zhang has contributed to topics such as:

  • Metabolomics and Mass Spectrometry Studies
  • Alcohol Consumption and Health Effects
  • Liver Disease Diagnosis and Treatment
  • Immune cells in cancer
  • Gut microbiota and health
  • Cancer, Hypoxia, and Metabolism
  • Extracellular vesicles in disease

The researcher has published in frequent venues like:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Science Advances
  • Frontiers in Pharmacology
  • Metabolites
  • SSRN Electronic Journal

Xiang Zhang's recent papers include:

  • "Tumor-derived exosomes drive immunosuppressive macrophages in a pre-metastatic niche through glycolytic dominant metabolic reprogramming," 2021, Cell Metabolism
  • "High-fat diet-induced upregulation of exosomal phosphatidylcholine contributes to insulin resistance," 2021, Nature Communications
  • "Plant-derived exosomal microRNAs inhibit lung inflammation induced by exosomes SARS-CoV-2 Nsp12," 2021, Molecular Therapy
  • "Transcription factor c-Maf is a checkpoint that programs macrophages in lung cancer," 2020, Journal of Clinical Investigation
  • "Inducing trained immunity in pro-metastatic macrophages to control tumor metastasis," 2023, Nature Immunology

Frequent collaborators in their research include:

  • Craig J. McClain
  • Liqing He
  • Xinmin Yin
  • Jun Yan
  • Wenke Feng

Best Publications

  • A Picoliter-Volume Mixer for Microfluidic Analytical Systems

    Bing He;Brian J. Burke;Xiang Zhang;Roujian Zhang

  • Strategy for qualitative and quantitative analysis in proteomics based on signature peptides.

    Junyan Ji;Asish Chakraborty;Ming Geng;Xiang Zhang

  • High-fat diet-induced upregulation of exosomal phosphatidylcholine contributes to insulin resistance

    Anil Kumar;Kumaran Sundaram;Jingyao Mu;Gerald W. Dryden

  • Probiotic Lactobacillus rhamnosus GG Prevents Liver Fibrosis Through Inhibiting Hepatic Bile Acid Synthesis and Enhancing Bile Acid Excretion in Mice.

    Yunhuan Liu;Kefei Chen;Kefei Chen;Fengyuan Li;Zelin Gu

  • Multi-dimensional liquid chromatography in proteomics—A review

    Xiang Zhang;Aiqin Fang;Catherine P. Riley;Mu Wang

  • Proteomics of glycoproteins based on affinity selection of glycopeptides from tryptic digests

    M. Geng;X. Zhang;M. Bina;F. Regnier

  • Intestinal HIF-1α deletion exacerbates alcoholic liver disease by inducing intestinal dysbiosis and barrier dysfunction

    Tuo Shao;Tuo Shao;Cuiqing Zhao;Cuiqing Zhao;Fengyuan Li;Zelin Gu

  • Radical Acylfluoroalkylation of Olefins through N‐Heterocyclic Carbene Organocatalysis

    Jun-Long Li;Yan-Qing Liu;Wen-Lin Zou;Rong Zeng

  • Integrative biological analysis of the APOE*3-leiden transgenic mouse.

    Clary B. Clish;Eugene Davidov;Matej Oresic;Thomas N. Plasterer

  • Quantitative proteomics strategy involving the selection of peptides containing both cysteine and histidine from tryptic digests of cell lysates.

    Shihong Wang;Xiang Zhang;Fred E Regnier

  • METHOD FOR PROTEIN IDENTIFICATION AND QUANTIFICATION IN COMPLEX MIXTURES UTILIZING AFFINITY SELECTION OF CONSTITUENT PEPTIDE FRAGMENTS

    Regnier Fred E

  • Detection of an Extended Human Volatome with Comprehensive Two-Dimensional Gas Chromatography Time-of-Flight Mass Spectrometry

    Michael Phillips;Renee N. Cataneo;Anirudh Chaturvedi;Peter D. Kaplan

  • Plant-Derived Exosomal Nanoparticles Inhibit Pathogenicity of Porphyromonas gingivalis

    Kumaran Sundaram;Daniel P. Miller;Anil Kumar;Yun Teng

  • Regiodivergent construction of medium-sized heterocycles from vinylethylene carbonates and allylidenemalononitriles

    Xiang Zhang;Xiang Zhang;Xiang Li;Jun-Long Li;Qi-Wei Wang

  • Data pre-processing in liquid chromatography--mass spectrometry-based proteomics

    Xiang Zhang;John M. Asara;Jiri Adamec;Mourad Ouzzani

  • Chronic Alcohol Exposure Disturbs Lipid Homeostasis at the Adipose Tissue-Liver Axis in Mice: Analysis of Triacylglycerols Using High-Resolution Mass Spectrometry in Combination with In Vivo Metabolite Deuterium Labeling

    Xiaoli Wei;Xue Shi;Wei Zhong;Yantao Zhao

  • Development of GCxGC/TOF-MS metabolomics for use in ecotoxicological studies with invertebrates

    Kimberly Ralston-Hooper;Amber Hopf;Cheolhwan Oh;Xiang Zhang

  • Stereoselective Construction of Halogenated Quaternary Carbon Centers by Brønsted Base Catalyzed [4+2] Cycloaddition of α-Haloaldehydes.

    Qiang Li;Liang Zhou;Xu-Dong Shen;Kai-Chuan Yang

  • DISCO: distance and spectrum correlation optimization alignment for two-dimensional gas chromatography time-of-flight mass spectrometry-based metabolomics.

    Bing Wang;Aiqin Fang;John Heim;Bogdan Bogdanov

  • Saturated and Unsaturated Dietary Fats Differentially Modulate Ethanol-Induced Changes in Gut Microbiome and Metabolome in a Mouse Model of Alcoholic Liver Disease.

    Irina A. Kirpich;Joseph Petrosino;Nadim Ajami;Wenke Feng

Frequent Co-Authors

Fred E. Regnier
Fred E. Regnier Purdue University West Lafayette
Huang-Ge Zhang
Huang-Ge Zhang University of Louisville
Jun Yan
Jun Yan University of Louisville
Changyu Shen
Changyu Shen Chinese Academy of Sciences
John M. Asara
John M. Asara Beth Israel Deaconess Medical Center
Mourad Ouzzani
Mourad Ouzzani Qatar Computing Research Institute
De-Shuang Huang
De-Shuang Huang Tongji University
Aruni Bhatnagar
Aruni Bhatnagar University of Louisville
Stephen Naylor
Stephen Naylor Mayo Clinic
Shirish Barve
Shirish Barve University of Louisville

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