His main research concerns Chromatography, Proteomics, Proteome, Mass spectrometry and Biochemistry. His studies deal with areas such as Peptide and Analytical chemistry as well as Chromatography. His Peptide study incorporates themes from Trypsin and Resolution.
His biological study spans a wide range of topics, including Bioinformatics, Biomarker, Serum chemistry, Plasma Metabolism and Computational biology. His study in Proteome is interdisciplinary in nature, drawing from both Tandem mass spectrometry, Bottom-up proteomics, Blood proteins, Fractionation and Membrane proteome. His study looks at the intersection of Mass spectrometry and topics like SELDI-TOF-MS with Biomarker identification, Diagnostic marker and Protein profiling.
Haleem J. Issaq mainly focuses on Chromatography, Analytical chemistry, High-performance liquid chromatography, Capillary electrophoresis and Proteomics. The Analytical chemistry study combines topics in areas such as Fluorescence and Elution. His research integrates issues of Quantitative analysis, Phase, Methanol and Silica gel in his study of High-performance liquid chromatography.
His Capillary electrophoresis study integrates concerns from other disciplines, such as Capillary electrophoresis–mass spectrometry, Free-flow electrophoresis and Buffer solution. His work carried out in the field of Proteomics brings together such families of science as Proteome, Metabolomics, Bioinformatics and Computational biology. His work in Proteome addresses subjects such as Peptide, which are connected to disciplines such as Trypsin and Peptide sequence.
His scientific interests lie mostly in Chromatography, Proteomics, Biomarker discovery, Metabolomics and Biomarker. Chromatography is closely attributed to Peptide in his study. His Proteomics research is multidisciplinary, incorporating elements of Proteome, Fractionation and Electrospray ionization.
His Biomarker discovery research includes themes of Biological fluids, Difference gel electrophoresis and Disease biomarker. His studies in Metabolomics integrate themes in fields like Metabolite, Computational biology and Principal component analysis. Haleem J. Issaq has researched Biomarker in several fields, including Cancer research, Potential biomarkers, Bioinformatics, Sarcosine and Prostate cancer.
His primary areas of investigation include Chromatography, Proteomics, Mass spectrometry, Biochemistry and High-performance liquid chromatography. The concepts of his Chromatography study are interwoven with issues in Metabolite and Trypsin. His Proteomics research is multidisciplinary, relying on both Biomarker, Proteome, Bioinformatics and Disease biomarker.
His Mass spectrometry research incorporates themes from Bladder cancer and Peptide. His Biochemistry research incorporates elements of Plasma Metabolism and Electrospray ionization. His High-performance liquid chromatography research integrates issues from Detection limit, Urine and Urinary bladder, Surgery.
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Characterization of the Low Molecular Weight Human Serum Proteome
Radhakrishna S. Tirumalai;King C. Chan;DaRue A. Prieto;Haleem J. Issaq.
Molecular & Cellular Proteomics (2003)
The SELDI-TOF MS Approach to Proteomics: Protein Profiling and Biomarker Identification
Haleem J. Issaq;Timothy D. Veenstra;Thomas P. Conrads;Donna Felschow.
Biochemical and Biophysical Research Communications (2002)
An investigation into the human serum "interactome".
Ming Zhou;David A. Lucas;King C. Chan;Haleem J. Issaq.
Serum and Plasma Proteomics
Haleem J. Issaq;Zhen Xiao;Timothy D. Veenstra.
Chemical Reviews (2007)
Measuring fifteen endogenous estrogens simultaneously in human urine by high-performance liquid chromatography-mass spectrometry.
Xia Xu;Timothy D Veenstra;Stephen D Fox;John M Roman.
Analytical Chemistry (2004)
MYC-driven accumulation of 2-hydroxyglutarate is associated with breast cancer prognosis
Atsushi Terunuma;Nagireddy Putluri;Prachi Mishra;Ewy A. Mathé.
Journal of Clinical Investigation (2014)
Quantitative Measurement of Endogenous Estrogens and Estrogen Metabolites in Human Serum by Liquid Chromatography-Tandem Mass Spectrometry
Xia Xu;John M. Roman;Haleem J. Issaq;Larry K. Keefer.
Analytical Chemistry (2007)
Peer Reviewed: SELDI-TOF MS for Diagnostic Proteomics
Haleem J. Issaq;Thomas P. Conrads;DaRue A. Prieto;Radhakrishna Tirumalai.
Analytical Chemistry (2003)
The role of separation science in proteomics research.
Haleem J. Issaq.
Proteomic patterns: their potential for disease diagnosis.
Zhen Xiao;DaRue Prieto;Thomas P. Conrads;Timothy D. Veenstra.
Molecular and Cellular Endocrinology (2005)
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