World's Best Scientists 2026 revealed!

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Genetics

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98
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Molecular Biology

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563
National Ranking
309

Overview

Brian Seed is affiliated with Harvard University in the United States and works primarily in the fields of Immunology and Microbiology as well as Medicine. Their research spans several interconnected areas, including immune cell function and interaction, IL-33, ST2, and ILC pathways, asthma and respiratory diseases, the reproductive system and pregnancy, the impact of COVID-19 on reproduction, and immune responses and vaccinations.

Their recent publications reflect these research interests:

  • Intestinal microbes influence development of thymic lymphocytes in early life (2020) - Proceedings of the National Academy of Sciences
  • The Knockout Mouse Project (2020) - UNC Libraries
  • Prenatal maternal infection promotes maternal microchimeric cells to alter infection risk in male offspring (2025) - bioRxiv (Cold Spring Harbor Laboratory)

Frequent coauthors include Caryn Porter, Bobby J. Cherayil, Nitya Jain, Maria Ennamorati, and Chithirachelvi Vasudevan. Their collaborations indicate a focus on immunological and microbiological research themes.

Brian Seed's work has been published in venues such as:

  • Proceedings of the National Academy of Sciences
  • UNC Libraries
  • bioRxiv (Cold Spring Harbor Laboratory)

Their work contributes to subfields including Immunology, Physiology, and Obstetrics and Gynecology, highlighting interdisciplinary engagement between immune system function and reproductive health. Research topics closely associated with their work emphasize the interplay between immune responses and various physiological states such as pregnancy and infectious disease impacts.

Best Publications

  • PPAR-γ agonists inhibit production of monocyte inflammatory cytokines

    Chengyu Jiang;Adrian T. Ting;Brian Seed

  • CD44 is the principal cell surface receptor for hyaluronate.

    Alejandro Aruffo;Ivan Stamenkovic;Michael Melnick;Charles B. Underhill

  • Endothelial leukocyte adhesion molecule 1: an inducible receptor for neutrophils related to complement regulatory proteins and lectins

    Michael P. Bevilacqua;Siegfried Stengelin;Michael A. Gimbrone;Brian Seed

  • Fas triggers an alternative, caspase-8-independent cell death pathway using the kinase RIP as effector molecule.

    Nils Holler;Rossana Zaru;Olivier Micheau;Margot Thome

  • Recognition by ELAM-1 of the sialyl-Lex determinant on myeloid and tumor cells

    Gerd Walz;Alejandro Aruffo;Waldemar Kolanus;Michael Bevilacqua

  • Molecular cloning of the CD2 antigen, the T-cell erythrocyte receptor, by a rapid immunoselection procedure.

    Brian Seed;Alejandro Aruffo

  • Cloning and expression of the human interleukin-6 (BSF-2/IFN beta 2) receptor

    Katsuhiko Yamasaki;Tetsuya Taga;Yuuichi Hirata;Hideo Yawata

  • Membrane Compartmentation Is Required for Efficient T Cell Activation

    Ramnik Xavier;Todd Brennan;Qingqin Li;Christine McCormack

  • Molecular cloning of a CD28 cDNA by a high-efficiency COS cell expression system

    Alejandro Aruffo;Brian Seed

  • RIP : a novel protein containing a death domain that interacts with Fas/APO-1 (CD95) in yeast and causes cell death

    Ben Z. Stanger;Ben Z. Stanger;Philip Leder;Philip Leder;Tae Ho Lee;Emily Kim

  • Tumor Induction of VEGF Promoter Activity in Stromal Cells

    Dai Fukumura;Ramnik Xavier;Takeyuki Sugiura;Yi Chen

  • An LFA-3 cDNA encodes a phospholipid-linked membrane protein homologous to its receptor CD2

    Brian Seed

  • A simple phase-extraction assay for chloramphenicol acyltransferase activity

    Brian Seed;Jenq-Yunn Sheen

  • Molecular cloning and expression of a new member of the nerve growth factor receptor family that is characteristic for Hodgkin's disease.

    Horst Dürkop;Ute Latza;Michael Hummel;Florian Eitelbach

  • A PCR primer bank for quantitative gene expression analysis

    Xiaowei Wang;Brian Seed

  • A lymphocyte molecule implicated in lymph node homing is a member of the cartilage link protein family

    Ivan Stamenkovic;Martine Amiot;John M. Pesando;Brian Seed

  • PrimerBank: a resource of human and mouse PCR primer pairs for gene expression detection and quantification

    Athanasia Spandidos;Xiaowei Wang;Huajun Wang;Brian Seed

  • Codon usage limitation in the expression of HIV-1 envelope glycoprotein

    Jürgen Haas;Eun-Chung Park;Brian Seed

  • Dynamic imaging of collagen and its modulation in tumors in vivo using second-harmonic generation.

    Edward Brown;Trevor McKee;Emmanuelle diTomaso;Alain Pluen

  • A B-lymphocyte activation molecule related to the nerve growth factor receptor and induced by cytokines in carcinomas.

    I. Stamenkovic;E. A. Clark;B. Seed

Frequent Co-Authors

Ramnik J. Xavier
Ramnik J. Xavier Broad Institute
Andrew S. Peterson
Andrew S. Peterson Stanford University
Alejandro Aruffo
Alejandro Aruffo Syngenta (United States)
Ivan Stamenkovic
Ivan Stamenkovic Harvard University
David Simmons
David Simmons Western Sydney University
Rakesh K. Jain
Rakesh K. Jain Harvard University
Dai Fukumura
Dai Fukumura Harvard University
Mason W. Freeman
Mason W. Freeman Harvard University
André Veillette
André Veillette University of Montreal
Winfried F. Pickl
Winfried F. Pickl Medical University of Vienna

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