World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
62
Citations
24900
World Ranking
10528
National Ranking
4568

Overview

Mason W. Freeman is affiliated with Harvard University in the United States and focuses on research within the field of Medicine. Their work primarily addresses topics related to endocrinology, diabetes, metabolism, cardiology, surgery, and pharmacology.

The scientist's major fields of study include:

  • Medicine

Their subfields of study reflect a concentration on:

  • Endocrinology, Diabetes and Metabolism
  • Molecular Biology
  • Cardiology and Cardiovascular Medicine
  • Surgery
  • Pharmacology

Mason W. Freeman's research covers several main topics, including:

  • Hormonal Regulation and Hypertension
  • Diabetes Treatment and Management
  • Blood Pressure and Hypertension Studies
  • Metabolism, Diabetes, and Cancer
  • Adrenal Hormones and Disorders
  • Pharmacogenetics and Drug Metabolism
  • Ion Transport and Channel Regulation

Recent published papers authored or coauthored by Mason W. Freeman span from 2021 to 2025 and include:

  • Phase 2 Trial of Baxdrostat for Treatment-Resistant Hypertension, 2022, New England Journal of Medicine
  • Results from a phase 1, randomized, double-blind, multiple ascending dose study characterizing the pharmacokinetics and demonstrating the safety and selectivity of the aldosterone synthase inhibitor baxdrostat in healthy volunteers, 2022, Hypertension Research

Other notable papers associated with this research group, though not authored by Freeman, include:

  • An AAV-based, room-temperature-stable, single-dose COVID-19 vaccine provides durable immunogenicity and protection in non-human primates, 2021, Cell Host & Microbe
  • A 96-week, double-blind, randomized controlled trial comparing bexagliflozin to glimepiride as an adjunct to metformin for the treatment of type 2 diabetes in adults, 2022, Diabetes Obesity and Metabolism
  • Phase 2a Study of Baxdrostat in Primary Aldosteronism, 2025, New England Journal of Medicine

Mason W. Freeman frequently collaborates with several researchers, including:

  • Yuan-Di C. Halvorsen
  • Brian Murphy
  • Mary Bond
  • Jonathan Isaacsohn
  • John Paul Lock

The most common publication venues for Freeman's work and their collaborators are:

  • Diabetes Obesity and Metabolism
  • New England Journal of Medicine
  • Diabetes
  • Cell Host & Microbe
  • Hypertension Research

Best Publications

  • Pattern recognition receptors TLR4 and CD14 mediate response to respiratory syncytial virus.

    Evelyn A. Kurt-Jones;Lana Popova;Laura Kwinn;Lia M. Haynes

  • C/EBPalpha induces adipogenesis through PPARgamma: a unified pathway.

    Evan D. Rosen;Chung-Hsin Hsu;Xinzhong Wang;Shuichi Sakai

  • A G protein-linked receptor for parathyroid hormone and parathyroid hormone-related peptide

    Harald Jüppner;Abdul Badi Abou-Samra;Mason Freeman;Xiang F. Kong

  • Type I macrophage scavenger receptor contains α-helical and collagen-like coiled coils

    Tatsuhiko Kodama;Mason Freeman;Mason Freeman;Lucia Rohrer;James Zabrecky

  • Scavenger Receptors Class A-I/II and CD36 Are the Principal Receptors Responsible for the Uptake of Modified Low Density Lipoprotein Leading to Lipid Loading in Macrophages

    Vidya V. Kunjathoor;Maria Febbraio;Eugene A. Podrez;Kathryn J. Moore

  • Expression cloning of a common receptor for parathyroid hormone and parathyroid hormone-related peptide from rat osteoblast-like cells: a single receptor stimulates intracellular accumulation of both cAMP and inositol trisphosphates and increases intracellular free calcium

    A B Abou-Samra;H Jüppner;T Force;M W Freeman

  • Reduced atherosclerosis in MyD88-null mice links elevated serum cholesterol levels to activation of innate immunity signaling pathways.

    Harry Björkbacka;Vidya V Kunjathoor;Kathryn J Moore;Stephanie Koehn

  • Scavenger Receptors in Atherosclerosis: Beyond Lipid Uptake

    Kathryn J. Moore;Mason W. Freeman

  • The role of PPAR-γ in macrophage differentiation and cholesterol uptake

    Kathryn J. Moore;Evan D. Rosen;Michael L. Fitzgerald;Felix Randow

  • Coiled-coil fibrous domains mediate ligand binding by macrophage scavenger receptor type II

    Lucia Rohrer;Mason Freeman;Mason Freeman;Tatsuhiko Kodama;Marsha Penman

  • CD36 Mediates the Innate Host Response to β-Amyloid

    Joseph B. El Khoury;Kathryn J. Moore;Terry K. Means;Josephine Leung

  • Loss of receptor-mediated lipid uptake via scavenger receptor A or CD36 pathways does not ameliorate atherosclerosis in hyperlipidemic mice

    Kathryn J. Moore;Vidya V. Kunjathoor;Stephanie L. Koehn;Jennifer J. Manning

  • Effect of Patiromer on Serum Potassium Level in Patients With Hyperkalemia and Diabetic Kidney Disease: The AMETHYST-DN Randomized Clinical Trial.

    George L. Bakris;Bertram Pitt;Matthew R. Weir;Mason W. Freeman

  • An ancient, highly conserved family of cysteine-rich protein domains revealed by cloning type I and type II murine macrophage scavenger receptors.

    Mason Freeman;John Ashkenas;D. J G Rees;David M. Kingsley

  • Ascorbic acid oxidation product(s) protect human low density lipoprotein against atherogenic modification. Anti- rather than prooxidant activity of vitamin C in the presence of transition metal ions.

    K L Retsky;M W Freeman;B Frei

  • A CD36-initiated Signaling Cascade Mediates Inflammatory Effects of β-Amyloid

    Kathryn J. Moore;Joseph El Khoury;Lea A. Medeiros;Kinya Terada

  • The induction of macrophage gene expression by LPS predominantly utilizes Myd88-independent signaling cascades

    Harry Björkbacka;Katherine A. Fitzgerald;François Huet;Xiaoman Li

  • Requirement of JNK2 for Scavenger Receptor A-Mediated Foam Cell Formation in Atherogenesis

    Romeo Ricci;Grzegorz Sumara;Izabela Sumara;Izabela Rozenberg

  • Divergent response to LPS and bacteria in CD14-deficient murine macrophages.

    Kathryn J. Moore;Lorna P. Andersson;Robin R. Ingalls;Brian G. Monks

  • Postmenopausal hormone-replacement therapy.

    Kathryn A. Martin;Mason W. Freeman

Frequent Co-Authors

Kathryn J. Moore
Kathryn J. Moore New York University Langone Medical Center
Douglas T. Golenbock
Douglas T. Golenbock University of Massachusetts Chan Medical School
Henry M. Kronenberg
Henry M. Kronenberg Harvard University
John T. Potts
John T. Potts Harvard University
Brian Seed
Brian Seed Harvard University
Andrew D. Luster
Andrew D. Luster Harvard University
Evan D. Rosen
Evan D. Rosen Beth Israel Deaconess Medical Center
Gina M. Peloso
Gina M. Peloso Boston University
Bruce M. Spiegelman
Bruce M. Spiegelman Harvard University

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